Connective Tissue Flashcards Preview

PTRS 711 Exam 1 > Connective Tissue > Flashcards

Flashcards in Connective Tissue Deck (32):
1

Connective Tissue Functions

Connect
Protect
Support

2

Connective Tissue Components

Made of fibers, cells and ground substance

3

Fibers

Provide tensile strength
Main types are collagen and elastin

4

Collagen

Made up of tropocollagen

5

Cells

Either fixed or migratory

6

Ground Substance

Made up of water, GAG's and proteoglycans

7

GAG's

Negatively charged and resist pressure

8

Dense Connective Tissue

Ligament
Tendon
Outer layer of joint capsule

9

Loose Connective Tissue

Adipose
Areolar tissue
Surrounds blood vessels/nerves

10

Viscoelastic Material Properties

Time-dependent
Rate-dependent
Hysteresis

11

Time-Dependent

Longer load = greater deformation

12

Rate-Dependent

Better resists loads applied more quickly than slow

13

Hysteresis

Energy dissipates due to internal friction, leading to curve of deformation

14

Creep Phenomenon

Strain reaches equilibrium over period of time

15

Stress-Strain Curve

Strain is the deformation of tissue
Stress is the load placed on the tissue

16

Toe Region

Minimal stress

17

Elastic Region

Increased stress up to *yield* point
Elastic limit

18

Plastic Region

Past the last limit and will have permanent deformation

19

Failure Point

Complete rupture

20

Young's Modulus

How much a substance will deform in response to force

21

Cortical Bone

Outer perimeter
Resist torsion and bending

22

Cancellous Bone

Metabolic activity
Highly vascular

23

Wolff's Law

Bone is laid down in areas of high stress and resorbed in areas of low stress

24

Cartilage Zone

Superficial (horizontal collagen) (1)
Transitional zone (arch-like collagen) (2)
Deep zone (perpendicular collagen) (3)
Zone of calcified cartilage (4)

25

Tendons

Type 1 collagen fibers
Oriented in line of tension
Transmit muscle force to bones
Poor blood supply
Myotendinous junction is weakest

26

Ligaments

Type 1 collagen fibers
Oriented in line of tension
Provide joint stabilization at end range
Bone to bone

27

Bone Optimal Stimulus

Loading along axis of bone

28

Cartilage Optimal Stimulus

Intermittent compression and decompression

29

Ligaments/Tendons

Tensile stress in the line of fiber orientation

30

Aging on Connective Tissue

Decreased water content, elasticity, maximal strength and adaptability

31

Diabetes on Connective Tissue

Increased cross-linkage of fibers (greater stiffness and risk for damage)

32

Immobilization on Connective Tissue

Osteoporosis
Decrease water content
Atrophy of cartilage
Atrophy at MTJ (dec tendon strength)
Atrophy/disorganization of ligament fiber arrangement