Context: WHAT NOW? pyruvate's fate

Question 1

Aerobic conditions

Answer 1

If O is sufficient, send pyruvate into PDH complex into the citric acid cycle, then ETC then ox phos. Allows you to make a lot of ATP

Question 2

anaerobic conditions

Answer 2

If O insufficent, do homo lactic fermentation. Take pyruvate and make lactate, allows to make back NAD+.
Only get 2 ATP from glycolysis.
REACTION 11 (lactate and NAD+ for GAPDH)

Question 3

What reaction is reoxidized NADH (from NAD+) being used in?

Answer 3

GAPDH