control of respiration Flashcards

1
Q

Respiration is under automatic control via centers in the ______ and under voluntary control via the _________

A

Respiration is under automatic control via centers in the medulla and under voluntary control via the cerebral cortex

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2
Q

DRG contains primarily

A

inspiratory neurons

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3
Q

ramp signal

A

initial weak AP but gradually increases in amplitude every 6 sec

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4
Q

neurons to the DRG connect to

A

inspiratory muscles by the phrenic nerve and the external intercostal by thoracic spinal nerve

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5
Q

DRG receive input from

A

peripheral cardiopulmonary sensorts

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6
Q

Botzinger complex actas as a _____ and it is found

A

acts as a pacemaker (generated respiratory rhythm) and it is located in the upper part of the VRG

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7
Q

lower part of VRG contains both

A

inspiratory and expiratory neurons

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8
Q

VRG increase the diameted of ______ during inspiration

A

upper airways

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9
Q

caudal region of the VRG sends output of the

A

expiratory muscles (internal intercostals and abdomonal muscles)

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10
Q

how long is resting breathing

A

around 3 sec

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11
Q

when are expiraotyr neurons in the VRG are needed

A

during exercise

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12
Q

the inspiratory and expiratory neurons in the medulla exhibit

A

reciprocal inhibition

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13
Q

The apneustic center, located in the_______ just above the medulla, may exhibit an ______ affect on the DRG and VRG and prolong the ramp action potentials.

A

The apneustic center, located in the lower pons just above the medulla, may exhibit an excitatory affect on the DRG and VRG and prolong the ramp action potentials.

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14
Q

pneumotaxic center is located in the _____ and appears to

A

located in the upper pons and appears to “switch-off” inspiration and thus may regulate inspiratory volume

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15
Q

can cortical centers override functions?

A

yep, it can control breathing

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16
Q

carotid and aortic bodies respond to changes in

A

PaO2, PaCO2 and pH

chemoreceptors

17
Q

how to the signals from carotid an aortic bodies sreach the DRG

A

nerves IX and X

18
Q

Glomus cells are

A

chemosensors

19
Q

which body is more sensitive to hypoxia

A

carotid more than the aortic

20
Q

Higher PaCO2 actually depresses ventilation and leads to CO2 narcosis.

21
Q

will a decrease in PaO2 results in a more sensitive response of chemosensors when combined with a rise in PaCO2

A

yepppppp, it would lead to a greater stimulation to ventilation

22
Q

The response of chemo-receptors to both increased PaCO2 and decreased PaO2 is enhanced at ______ pH.

23
Q

central chemoreceptors are located ________ and provide sensory input to the _____

A

located in the medulla and provide sensory input to the DRG

24
Q

dentral chemoreceptors are stimulated by changes in the

A

pH of the CSF

25
how does H+ diffuse through blood-brain barrier
as CO2
26
Hering-Breuer reflex
overinflation of the lung sends signals via the vagus nerve to the pneumotaxic center to terminate inspiration
27
slowly adapting stretch receptors
mechanoreceptos located within the tracheobronchial tree that fire when the lung volume increases
28
apneustic breathing
deep and prolonged inspiration
29
rapidly adapting stretch receptor occur in the
upper airways
30
sneeze reflex receptors located in the ______ and respond to
nasal mucosa and pharynx and respond to distension of the tissue and irritation
31
cough receptors located in
larynx, trachea and bronchi
32
sneeze and cough are caused by
irritants
33
irritant receptors ______ respiratory centers to augment respiratory activity and to _____ airways to promote ________ breathing to limit penetration of the noxious agents.
irritant receptors stimulate respiratory centers to augment respiratory activity and to constrict airways to promote rapid, shallow breathing to limit penetration of the noxious agents.
34
J receptors respond to
J receptors respond to interstitial edema and engorgement of pulmonary capillaries.
35
when J receptors are stimulated the y
mediate closure of the larynx and tachypnea in response to pulm. embolism
36
chest wall mechanoreceptors detect
impediments to breathing and stimulate inspiratory activity
37
input from the cortex are absolute when it comes to breathing
nope; ventilatory drive from chemoreceptors are too strong