Controlling Blood Pressure Flashcards Preview

Urinary System > Controlling Blood Pressure > Flashcards

Flashcards in Controlling Blood Pressure Deck (18)
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1
Q

what is the short term response to control blood pressure

A

baroreceptor response

2
Q

where are baroreceptors found

A

in the arch of the aorta and carotid sinus

3
Q

what do the baroreceptors cause to happen in the kidney

A

the myogenic reflex and tubuloglomerular feedback

4
Q

what are the long term regulations for BP

A
RAAS
SNS
ADH
ANP
prostaglandins
5
Q

what does ADH do

A

increases water reabsorption in the collecting duct through aqua porin 2 channels

6
Q

what stimulates the release of ADH

A

increase in plasma osmolality or severe hypovolemia

7
Q

what does ANP do

A

inhibits Na reabsorption and causes vasodilation

8
Q

what is ANP released in response to

A

atrial stretch

9
Q

what do prostaglandins do

A

cause vasodilation in afferent arteriole

10
Q

what does the SNS do to affect BP in the kidneys

A
  • reduces renal blood flow through vasoconstriction

- stimulates renin release

11
Q

what cells produce renin

A

granular cells in the juxtaglomerular apparatus

12
Q

what does angiotensin 2 do

A
causes production of aldosterone 
ADH release
vasoconstrictor afferent and efferent arterioles 
sympathetic stimulation 
increases Na reabsorption
13
Q

how does angiotensin 2 increase sodium reabsorption

A

binds to angiotensin 2 receptors to stimulate NHE channels

14
Q

what does aldosterone do

A

stimulates Na and water reabsorption by activating ENaC

15
Q

what cells does aldosterone work on

A

principal cells in the collecting duct

16
Q

give some causes of secondary hypertension

A

renal artery stenosis, primary aldosteronism, coarchtation of the aorta, cushings syndrome

17
Q

how do you diagnose primary aldosteronism

A

compare the levels of aldosterone to renin (as renin should not have increased)

18
Q

how can liquorice cause an increase in BP

A

prevents conversion of cortisol so that it can bind to aldosterone receptors