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Question 1

What is the relation of the SRY gene and female structures?

Answer 1

Abscence of SRY gene results in formation of ovaries from primordial gonadal cortex.

Question 2

What is the relation of AMH and female structures?

Answer 2

Absence of AMH [from Sertoli cells] → Mullerian duct forms female internal structures → Fallopian tube, uterus and upper part of the vagina.

Question 3

What structures does estrogen stimulate the formation of?

Answer 3

Estrogen [ovary] stimulate development of external structures: lower vagina, clitoris, labia minora, labia majora.

Question 4

What female structures form during 7-12 weeks of development?

Answer 4

Meiosis of oogonia and arrest at first meiotic prophase
Ovarian organogenesis
Formation of primordial follicles

Question 4

What female structures form during 11-12 weeks of development?

Answer 4

Oviducts, uterus, cervix, external genitalia, and vagina

Question 5

What female structures form during 20-25 WEEKS
weeks of development?

Answer 5

Primary follicles in ovary

Question 6

What role does leptin have in female puberty?

Answer 6

Leptin [adipose tissue], has a permissive role in hypothalamic maturation at puberty.