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What are the roles of sertoli cells in spermatogenesis?
What is decapacitation?
Decapacitation regulates the fertilizing ability of spermatozoa by controlling surface-associated proteins.
(Basically makes it inactive)
How is decapacitation maintained?
It depends on sperm surface-associated proteins that are controlled by the interaction between cholesterol, phospholipidsandfibronectin-like substances.
These substances are delivered via small vesicles inseminal vesicles and released in secretions from theepididymisand accessory glands.
What is capicatation
basically activation of sperm so it can fertilize the egg
What changes occur for capcitation to take place?
- Change in membrane fluidity due to the removal of cholesterol from the sperm membrane
- The removal of glycoproteins from the membrane that blocks sperm binding to the egg.
- A change in membrane potential that permit Ca2+ to enter the sperm and facilitate the acrosome reaction.
- Phosphorylation of numerous proteins
Where does capicatation occur?
Capacitation occurs in the oviduct
What should the post acrosomal region not contain?
the post-acrosomal region should not contain any vacuoles
What is globozoospermia?
a condition where sperm cells are abnormally round (globular) and have defects in their structure