CP - Transfusion Medicine

Question 1

Storage preparation of FFP

Validity

Answer 1

-18*C within 8 hours

Stored for 1 year

Question 2

Temp storage of FFP for 7 years

Answer 2

-65*C

Question 3

When FFP is stored what temp will it be stored and used within 24 hours

Answer 3

1-6*C

Question 4

When FFP is not used, what is the preparation to maintain for 5 days

Answer 4

Factor 5 and 8

Question 5

Cryoprecipitate is a cold precipitated concentration of _____________

Answer 5

Factor 8

Question 6

Indications for Cryoprecipitate

Answer 6

Treatment of Hemophilia A
Source fo Fibrinogen
Transfusion or congenital fibrinogen deficiency

Question 7

Platelet concentrate must contain at least _______amt of platelets

Answer 7

5.5x10^10 Platelet/unit

Question 8

Platelet concentrate should be stored in what temp if stored for 5 days

Answer 8

20-24*C

Question 9

Platelet concentrate is _____ to _____ mL of plasma

Answer 9

30-50 mL

Question 10

Platelet Concentrate when thawed should be transfused within how many hours

Answer 10

4 hours

Question 11

Indication for Platelet Concentrate

Answer 11

Bleeding (DIC), Thrombocytopenia
Abnormal Platelet Count
Propylaxis under 5-10K/ul

Question 12

Steroids are given prior to procedure and exposed to Hydroxyethyl starch

Answer 12

Granulocyte Concentrate

Question 13

Storage of Granulocyte Concentrate within 24 hours

Answer 13

20-24*C

Question 14

True or False: Granulocyte Concentrate transfusion doesn’t need to be ABO & Rh, Crossmatch compatible

Answer 14

FALSE

Question 15

Cyroprotective Agent that is a Large molecule form of a shell around the cell
Prevents loss of water and subsequent dehydration

Answer 15

Non Penetrating - Hydroxyethyl Starch

Question 16

Cryoprotective Agent that has a small molecule that cross cell membrane
Prevents wate from migrating outward
Extracellular ice formation - prevents intracellular dehydration

Answer 16

Penetrating - Glycerol

Question 17

High or Low Glycerol:
Increased Cryoprotection
Slow uncontrolled freezing process
Require larger volume of wash solution (Stored at -80*C)
Most widely used

Answer 17

High Glycerol (40% weight per volume)

Question 18

High or Low Glycerol:
Minimal Cyoprotection
Very Rapid, more controlled freezing
Liquid nitrogen
Routinely use (stored at -120* C)

Answer 18

Low Glycerol

Question 19

Treatment for Delayed Hemolytic reactions

Answer 19

IVIG

Question 20

Dyspnea, hypoxemia, tachycardia, fever, hypotension and cyanosis - during or within hours of transfusion

Answer 20

Transfusion related acute lung injury (TRALI)

Question 21

What can you see in a Radiograph of TRALI

Answer 21

Generalized pattern of Pulmonary Edema