CPEO And Myositis

Question 1

What is chronic progressive external ophthalmoplegia, and features

Answer 1

• mitochondrial disorder
• associated with Kearns sagre syndrome

Features
- progressive symmetrical loss of mobility
- usually upgaze is the first to be affected
- normal pupils and accommodation
- slowly progressive diplopia
- late stage has no eye movement due to fibrosis

Question 2

CPEO management

Answer 2

• Fundoscopy
• ECG
• orthotic assessment
• ptosis props/fresnels

Question 3

Ocular myositis - signs and symptoms

Answer 3

• inflammatory swelling of one or more EOMs
• pseudotumour
• Px presents with painful diplopia

Signs/symptoms
- acute pain
- proptosis
- diplopia
- oedema
- chemosis
- underlying inflammatory disease
- sinusitis or cellulitis

Question 4

Diagnosis of ocular myositis

Answer 4

• acute onset but can be chronic
• CT scan shows inflammation
• ensur not rhabdomyosarcoma