Cranial nerve lesions Flashcards

1
Q

What cranial nerves can have lesions?

A

3-12 from brainstem

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2
Q

What are 3 conditions of cranial nerves?

A
  • Bell’s palsy
  • Trigeminal neuralgia
  • Third nerve palsy
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3
Q

Define Bell’s palsy

A

Lower motor neuron weakness of cranial nerve VII (facial nerve) → acute peripheral facial palsy

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4
Q

What are causes of Bell’s palsy?

A
  • idiopathic
  • Thought to be related to inflammation and oedema of the facial nerve secondary to viral infection or autoimmunity
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5
Q

What are symptoms of Bell’s palsy?

A
  • Presents with rapid onset (<72 Hours) of unilateral facial weakness
    post-auricular/ear pain
  • Difficulty chewing
  • incomplete eye closure
  • drooling
  • tingling in cheek/mouth
  • hyperacusis - decrease in everyday sound tolerance
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6
Q

What are signs of Bell’s palsy?

A
  • ocular dryness
  • decreased taste
  • Asymmetrical smile
  • Drooping of the corner of the mouth
  • Drooping of the eyebrow
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7
Q

Why might there be drooling and decreased taste in Bell’s palsy?

A

The facial nerve terminates within the parotid gland

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8
Q

How do you diagnose Bell’s palsy?

A

Clinical diagnosis - based on unilateral facial weakness, of rapid onset, without forehead sparing (with forehead sparing suspected UMN lesion)

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9
Q

What investigations would you do for Bell’s palsy?

A
  • Bloods
  • Neuroimaging, LP
  • Consider HIV test
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10
Q

How do you treat Bell’s palsy?

A
  • Management largely supportive, but prednisolone may be used in those presenting within 72 hours of onset
  • antiviral treatment e.g acyclovir can be considered
  • eye care - lubricating drops, taping eye when sleeping, sunglasses outdoors, referral to ophthalmology considered
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11
Q

Define third nerve palsy

A

A third nerve palsy refers to damage to the oculomotor nerve

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12
Q

What does the oculomotor nerve do?

A

→ Pupil: parasympathetic fibres run superficially within the nerve to cause pupil constriction
→ Eyelid: innervates the levator palpebrae superioris that elevates the eyelid
→ Extraocular muscles: innervates all the extraocular muscles except the superior oblique and lateral rectus muscle

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13
Q

What are the causes of third nerve palsy?

A

→Tumour
→Haemorrhage
→Ischaemia (stroke)
→meningitis
→aneurysm
→trauma

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14
Q

What are signs of third nerve palsy?

A

→ Ipsilateral ptosis with a down and out appearance
→ pupil dilation
→ loss of light reflex
→ Neck stiffness if there is subarachnoid haemorrhage or meningitis

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15
Q

What are symptoms of third nerve palsy?

A

→ Diplopia
→ Ptosis - drooping eyelid
→ pain
→ severe headache
→ Meningism - headache, neck stiffness, photophobia - subarachnoid haemorrhage/meningitis

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16
Q

How do you treat third nerve palsy?

A

Treat underlying disease

17
Q

What investigations do you do for third nerve palsy?

A
  • CT/MRI head
  • LP
18
Q

What are signs of a CN4 lesion?

A
  • Diplopia looking down
  • Rare- always due to trauma
19
Q

What are signs of a CN6 lesion?

A

Adducted eye, sign of increased ICP

20
Q

What are signs of a CN5 lesion?

A
  • Jaw deviates towards affected side
  • Loss of corneal reflex
  • Trigeminal neuralgia
    (sensory pain/ motor jaw pain in V1/V2/V3)
21
Q

What are signs of a CN7 lesion?

A

Facial droop w/ no forehead sparing
- Bell’s palsy, parotid inflammation

22
Q

What are signs of a CN8 lesion?

A
  • Hearing loss
  • Loss of balance
  • Skull change (eg Paget’s), compression, middle ear disease
23
Q

What are signs of CN9+10 lesion?

A
  • Impaired gag reflex (+swallowing, resp, vocal issues)
  • Jugular foramen lesion
24
Q

What are signs of a CN11 lesion?

A

Can’t shrug shoulders/turn head vs resistance

25
Q

What are signs of a CN12 lesion?

A

Tongue deviation towards side of lesion