Critical Care Medicine Flashcards

(44 cards)

1
Q

What are some typical features of a critical care unit?

A
  • px are typically critically ill - suffering medical emergencies
  • px need continuous monitoring (ie vitals, O2, BP, Temp)
  • px often on more specialist equipment - ie ventilator, NG tubes
  • px are often bed boud - reduced mobility and often recover slowly (increased risk for DVT)
  • px are: nurse = 1 : 1
  • px are often ✅ sedated, ✅ ventilated, ✅ and on RRT
  • px leave not as fit as they came prior to being admitted - they need to be fit and likely to survice the intensieve care given on ITU ( extremely frail px may not survive and thus it may not be an option for them).
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2
Q

What care is offered in an ITU unit/ critical care unit?

A
  • airway + breathing support 🫁
  • circulatory support 🫀
  • sedation and analgesia 💊
  • sepsis management 🦠
  • Renal Replacement Therapy 🫘
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3
Q

What are the goals of offering the 5 types of care in critical care medicine?

A
  • they prioritise and allow px to recover from the reason for admission
  • maintain oxygen perfusion around the body - avoid decline
  • treat and remove problems and address new problems that the px may develop
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4
Q

What types of patients may be admitted to critical care?

A

Patients who have respiratory failure - ie *pneumonia, acute asthma, Covid - 19 *

Patients with cardiac instability - ie stroke, HTN crises, severe sepsis, septic shock etc

Px with neurlogical emergencies - stroke, status epileptics, TBI

Px who are acutely ill; medical emergencies - severe burns, DKA, sepsis , post op after medicl surgerys

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5
Q

What equipment is typically used for respiratory support?

A

A ventilator - which is used to deliver oxygen and remove co2 for patients who are unable to breathe properly

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6
Q

Give two examples of invasive mechanical ventilation?

A
  • Endo - tracheal tube
  • Tracheostomy
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7
Q

What is an ET tube?

A

It is a tube inserted via the mouth (adult) or the nose (kids) that that pumps oxygen and remove co2 to and from the lungs.

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8
Q

What is the benefit/ purpose of the balloon/cuff inside an ET tube?

A

The balloon/cuff inside is used to prevent aspiration into the lungs and to reduce the risk of pneumonia, as well as sealing the airways to prevent leaks as well as securing the tube in place to prevent accidental displacement

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9
Q

What are the negatives / downsides of being fitted with an ET tube?

A
  • px cant talk - consent + communication implicated!
  • px cant clean teeth alone - autonomy + hygiene
  • more difficult to breath
  • px may get very dry lips + mouth bc they cant close lips fully - v uncomfortable
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10
Q

What is a tracheostomy and why is it preferred among px requiring ventilation support?

A

This is a breathing tube inserted via a hole in the neck into the trachea allowing air to be pumped in

Px prefer it and it has a >er compliance bc it bypasses the mouth and so the oral complications associated with ET tube (ie dry mouth, consent, discomfort, communication , hygiene, etc are less of a problem).

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11
Q

What is the one semi downside for the patient, using a tracheostomy?

A
  • it will leave a scar on their neck
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12
Q

What is the goal of mechanical ventilation in px requiring respiratory support?

A
  • to keep the alveoli open and therefore allowing them to contract and relax gently to allow for adequate gas exchange.
    ⚠️ must avoid inflating TOO MUCH O2 via ventilation
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13
Q

What might happen if we inflate TOO much oxygen via ventilation?

A
  • 💥 barotrauma - ie the alveoli SNAPS
  • O2 toxicity ⛽️
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14
Q

What is the absolute limit of O2 we can administer/ prescribe?

A
  • no more than 6mL/kg
  • kg - lean body weight
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15
Q

What are the 3 main causes/ presentations of circulatory failure?

A
  • Inadequate pre - load
  • myocardial failure
  • maldistribution
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16
Q

What is inadequate pre - load?

A

When there isn’t enough blood returning back to the heart to fill the ventricles properly.

  • this may be due to hypovolemic - xs diuresis, vasodilation etc - basically there is not enough blood or fluid in the body and thus there is not enough blood to return to the heart.
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17
Q

How do we measure circulatory function?

A

Indirectly by looking at
- ABP (mainly used)
- CO ( LiDCO, PiCCO)
- bloods - troponin (increased in MI) and BNP (increased in HF)

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18
Q

What are the two main lines we use fir IV administration?

A
  1. Arterial line - obvs this is not IV its IA
  2. Central Venous Catheter
19
Q

What is the arterial line usually ised for and where can we insert it along the body?

A
  • ABP
  • radial, brachial and femoral artery
20
Q

Where is the Central venous catheter inserted along the body and what is it typically used for?

A
  • IJV, subclavian, femoral vein (last resort!)
  • used for drug administration, fluid resus, parenteral nutrition
21
Q

What is the benefit of using a multi - lumen CVC line?

A

We can administer multiple drugs that are incompatible with eachother at the same time

  • we can get 2, 3, 4,5 , 7 lumen lines
22
Q

What do we prescribe to treat inadequate pre - load?

A
  • BOLUS injection of 500ml of a crystalloid solution over 15 mins
    (Resus!)
23
Q

What are the investigations we would do first regardig assessing for inadequate pre - load?

A

Passive / straight leg raise
- if the px BP increases - rx fluid
- if the px BP is the same - no fluid is needed

24
Q

What is myocardial failure?

A

Cardiogenic shock where the patients CO is extremely LOW

(The px heart is not pumping enough blood out to the body!)

25
What kind of drugs should we be rx to treat myocardial failure?
- inotropics - to increase contractility of the heart and thus increase CO
26
What is the 1st line treatment of myocardial failure in an ITU setting? And what are the SE?
Dobutamine - inotropic SE - peripheral Ischaemia, tachycardia, tolerance
27
What is 2nd, and 3rd and 4th line treatment of myocardial failure in an ITU setting?
2nd - Adrenaline + inotropy and choronotropy - SE sudden death and chest discomfort ( 🐁 on chest) 3rd - Vasodilators (ie GTN, Isosorbide Dinitrate) and sodium nitroprusside - SE - postural hypotension, tolerance - advise px to sit when taking and remain seated for 5mins and then get up slowly when need to get up - na nitroporusside if left in sun - cyanide —> toxic! ⚠️ keep away from ☀️
28
What is maldistribution?
This when px have an adequate CO + BP but the blood flow is unevenly distributed across organs and tissues - leads to some organs being over or under perfused
29
What are some causes of maldistribution?
- anaphylaxis (causes capillary leaks, angiodema, vasodilation etc) - sepsis 🦠 - neurogenic shock 😳 - xs use of vasodilators
30
What is the main treatment aim regarding the treatment of maldistribution?
To selectively constrict the blood vessels to redirect / distribute the blood towards vital organs!
31
What types of drugs do we use in critical care to treat maldistribution and why?
Vasopressors - they increase blood pressure and induce vasoconstriction (to redirect blood flow to the vital organs)
32
What drugs do we use to treat maldistribution?
Noradrenaline - increases HR and Systemic Vascular Resistance (SE = peripheral ischaemia) Dopamine - inotropic at high doses - not widely used anymore bc of the SE (tachy, AF, MI) Vasopressin (ADH) - can cause extreme vasoconstriction and thus increase SVR
33
What is the main aim when treating px in ITU with sedation and analgesia?
- to keep them *comfortable* and rousable
34
What are the risks associated with Rx sedatives in critical care patients?
- sedation accumulation - px increasingly difficult to wake!
35
How can we avoid causing sedation accumulation in ITU px?
- briefly stop sedation - ie sedation holidays - allow the patient to wake up
36
Which drugs do we use to sedate patients?
1. Propofol - sedating anesthetic 2. Midazolam - can be administered IV inf :) 3. Alpha 2 adrenergic agonists (vasoconstrictors) - ie clonidine and dexmedotomidine (not widely used) 4. Paralysing agents (ie non polarising NMBS)- ie atracurium and rocuronium but these are more to control aggressive patients, ie to prevent excess omvement etc
37
What do we need to be aware of when prescribing paralysing agents?
- they are ❌ NON ANALGESIC and ❌ NON SEDATING ⚠️ THUS WE ONLY PRESCRIBE THEM TO PX WHO ARE ADEQUALTY SEDATED AND PAIN CONTROLLED! - otherwise they will be aware of the pain, or may be awake but are unable to move or talk!!! (Scary!)
38
39
what must we ensure when paralysing patients?
- they are fully sedated - thus not aware of the paralysis - their pain is fully controlled - cannot feel pain bc if they do but are paralysed they cannot move
40
How do we typically treat patients presenting with delirium?
- antipsychotics such as - ✅ levomepromazine - ✅ haloperidol Nb these drugs have a role in palliative care regarding treating nausea and vomiting
41
What do we typically prescribe for PAIN for patients in critical care?
OPIOIDS - remifentanil and fentanil - they have VERY RAPID ONSET OF ACTION and 😊 they are also SEDATING - they also have **short duration of action** thus we STOP them and assess if a px is rousable after 24hrs (ie if we sedated a trauma px with a MI or head injury immediately , we can wake them the next day when initial care has been implemented) Paracetamol howeer for px who are under 50kg - we can only rx a ax of 2 -3 g oer day
42
Generally how do we manage a patient with sepsis?
Sepsis 6 - IN - O2, fluids, and Abx - OUT - serial lactate, 2x blood cultures and urine output
43
What is the renal support typically offered for px admitted for acute renal failure?
- usualy renal replacement therapy - dialysis 3x a week
44
What is septic shock?
Sepsis + refractory (ie cant be corrected) hypotension - plasma expansion with a colloid is indicated