Fluids Flashcards

(57 cards)

1
Q

What is the best serial measurement for fluid balance and for calculating x px post operative fluid levels?

A
  • serial measurements of their weight
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2
Q

Describe the fluid compsition (H2O%) in a healthy adult?

A

The body is
40% solid ๐Ÿ’ช
60% H20/fluid ๐Ÿ’ง of which
- 20% of fluid is found extracellularly
- 40% intracellularly

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3
Q

How does fluid composition change with age

A

It decreases with age - older patients are drier and are at increased risk of dehydration
.

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4
Q

How much fluid should a person be drinking a day?

A

1.5 - 2L , but this is not standardised - you should be drinking water when you feel thirsty

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5
Q

Describe some ways in which we obtain fluid and lose fluid from our bodies?

A
  • fluid intake - food ๐Ÿฅ˜ + H2O drink ๐Ÿธ
  • fluid out - faeces ๐Ÿ’ฉ , urine ๐Ÿšฝ , sweat ๐Ÿ’ฆ , tears ๐Ÿ˜ญ , saliva ๐Ÿ’ง
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6
Q

Describe how the fluid balance changes with injury? ๐Ÿค•

A

When a person is injured more ADH is released AND capillaries increase in their leakyness - this results in an increase in :

  • water retention and sodium retention - this floods the affected area with fluid (oedema) and can lead to swelling and pa on nerves, discouraging movement and further trauma
  • the increased leakyness of the capillaries will result in increased albumin loss via fenestrations and release of cytokines , H2 and PG to the site of injury โ€”> brings inflamatory mediators to the site of damage for repair
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7
Q

Describe how the fluid balance changes when an injury is healed ๐Ÿ˜Š

A

The capillaries become LESS leaky - thus inflammatory cytokine and albumine etc return or remain in the bloo d

  • less peripheral oedema
  • albumin retention in the blood

The px excretes the xs fluid as URINE

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8
Q
A
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9
Q

What are ongoing fluid losses?

A

These are the continuous + measurable fluid losses that exceed the normal daily requirements

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10
Q

What are some typical causes of ongoing fluid losses?

A
  • vomiting, diarrhoea, xs sweat (ie fever) , surgery
  • stoma output!
  • polyuria
  • diabetes insipidus
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11
Q

What is the main ion found in the extracellular body fluid and what is its tyical serum ๐Ÿฉธ concentration?

A

SODIUM
- 135 - 145mmol/L

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12
Q

What is the main ion found in the intracellular body fluid and what is its plasma ๐Ÿฉธ concentration?

A

K+
Bc it is intracellular, the plasma levels are of course low and are not a true representation of how much potassium is in the body - typical levels are between 3.5 - 5.3 mmol/L

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13
Q

What is the typical range for [Cl] in the blood ๐Ÿฉธ

A

98 - 105 mmol/L

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14
Q

What is the osmolality of the blood? ๐Ÿฉธ

A

180 - 200 mOsm

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15
Q

What are the risks associated with administering fluids TOO quickly?

A
  • infusion reactions - anaphylactoid or skin reactions
  • brain damage
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16
Q

What are the 5 Rs of prescribing IV fluids?

A
  1. Resus
  2. Routine Maintenance
  3. Replacement
  4. Redistribution
  5. Re -assessment
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17
Q

What are the two main reasons we prescribe fluids in 2ndary care?

A

Acute Fluid resusitation - ie acute cases of hypovolemia

Maintenance fluids - for patients who cant maintain an adequate oral intake of fluids.

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18
Q

What are some causes of hypovolemia?

A
  • sepsis ๐Ÿฆ 
  • burns ๐Ÿ”ฅ
  • haemorrhage ๐Ÿฉธ
  • severe vomiting ๐Ÿคฎ or diarrhoea ๐Ÿ’ฉ
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19
Q

Why do we prescribe IV fluids to patients who are acutely hypovolemic?

A

Larger volumes are required to boost their circulating volume + they help to prevent patients experiencing SHOCK

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20
Q
A
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21
Q

What is hypovolemic shock?

A

Thus is when there is a reduced flood flow to organs due to reduced fluids circulating in the body

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22
Q

If a px presented to us with hypovolemic shock or acute hypovolemia or was an adult presenting with sepsis, what would be the 1st line treatment regarding IV fluids?

A
  • BOLUS OF 500ml of a crystalloid over 15mins that has at least 130 - 154 mmol/L of Na+)

(Eg Hartmans, 0.9% NaCl, or dextrose 5%)

  • Rx at least 30ml/kg in the 1st 3hrs
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24
Q

What are some pathological conditions that would make it difficult for a patient to maintain oral intake of fluids, thus requiring them to be rx maintenance fluids?

A
  • bowel obstruction
  • peri - operative px
25
What is the goal when prescribing maintenance fluids?
- โœ… replace + maintain ongoing fluid losses that - โœ… maintain hydration
26
What is the typical dose we give to px for maintenance fluids?
**25 - 30ml/kg of H2O** AND **1mmol/kg/day of Na + Cl** and **500 - 100g/day of glucose**
27
Are IV fluids typically administered during the daytime or the night time and why?
Usually during the day time - allows for wellbeing and px to sleep peacefully
28
Which patient group will require a reduced amount of fluids?
- elderly patients ๐Ÿ‘ต - frail patients ๐Ÿ‘ด๐Ÿผ - malnourished patients โŒ ๐Ÿฅ˜ - px with ๐Ÿซ˜ or ๐Ÿซ€ impairments
29
What are the two main types of fluids that we can prescribe to patients?
- crystalloid - colloidal
30
What is a crystalloid fluid?
A solution with **small H2O soluble molecules that easily move between blood vessels, tissue and semipermeable membranes** - ie they have electrolytes and glucose
31
Give 3 examples of crystalloid solutions?
NaCl 0.9% (normal saline) solution Haartmans solution (ringers lactate, haartmans lactate) Dextrose 5% solution
32
33
What is the main indication for Rx NaCl 0.9%?
Traumatic Brain Injury - the Na+ drawswater from the brain by creating an osmotic gradient โ€”> this prevents swelling and avoids โ€œconingโ€
34
What are the main indications for using crystalloid solutions as IV fluids?
- dehydration - mild blood loss - hypovolemic shock ๐Ÿ˜ฎ (thus resus!) - maintenance fluids
35
What are the downsides of rx a crystalloid over a colloid solution?
- ๐Ÿš‘ limited plasma expansion - needed for critical care - ๐Ÿฉธ its not very representative of the physiological body fluids - lacks proteins and the composotion of the electrolytes is optimised, slightly different to natural values
36
What is the main SE or complication of using NaCl 0.9%?
The [Cl-] is greater than that in normal blood composition - can lead to *hyperchloremic acidosis* and *vasoconstriction of the kidneys โ€”โ€”โ€”> AKI!!!*
37
What must HCPS do in order to prevent the developement of hyperchloremic acidosis in px prescribed NaCl 0.9% as a IV fluid?
โš ๏ธ This in px rx IV fluids containing >120mmol of Cl- HCPโ€™s MUST monitor the [Cl-] DAILY!
38
What are colloidal solutions?
Solutions with **LARGE MOLECULES** that **stay in the bloodstream** increasing oncotic pressure to draw water into blood vessels
39
40
Can colloidal solutions cross the semi - permeable membranes of cells?
NO - they remain in the bloodstream - hence they are so good for plasma expansion ๐Ÿš‘
41
Give 3 examples of colloidal solutions?
- albumin - dextran - HES - gelatins
42
What are the two main downsides of using colloidal solutions as IV fluids?
- there is a risk of anaphylaxis in some px - albumin is a blood product - can be ยฃยฃยฃ
43
What are some indications for the rx of colloidal solutions as IV fluids?
- **shock** - burns, sepsis and haemorrhage - **severe blood loss** - good bc they are more similar to the physiological composition - **plasma expansion** - ie providing a blood volume for the circulatory system
44
When do can we use/ when are colloidal IV fluids indicated in sepsis?
- if the patient presents with septic SHOCK - ie sepsis AND refractory hypotension
45
What is hyponatremia?
Low serum Na+
46
What are some causes for hyponatremia?
- severe diarrhoea or vomiting ๐Ÿคฎ - fluid overload (thus blood dilution) - xs ADH secretion - medications. - ie SSRIs, anti - psychotics (ie Risperidone), diuretics (thiazides!!) See cks
47
What are some symptoms of hyponatremia?
Nausea - vomiting - headaches - fonfusion - loss of energygy and - seizures - weakness - somnolence - extreme drowsiness
48
What are some symptoms of hypovolemia?
- tachycardia - postural hypotension - dry skin + mucous membranes - low urine output - decreased JVP - reduced skin turgur
49
What can continued chronic hyponatremia lead to?
- increased risk of falls, bone fractures, osteoporosis, gait instability, and concentration and cognitive deficits.
50
What is hypernatremia?
High serum Na+ levels >145mmol/L
51
What are some causes of hypernatremia?
- reduced water intake ie dehydration) - water losses are .er than sodium losses (ie very water diarrhoea, outflow diarrhoea)
52
What are some symptoms of hypernatreamia?
- px may present with lethargy - irritability - confusion - coma
53
Which electrolyte was responsible for the 1st NPSA alert and why?
Potassium (chloride) - KCL is a very strong solution and can kill patients
54
How can rapid admin/ xs admin of KCl cause harm in a patient?
- it may cause ๐Ÿซ€ arrest (heart stops beating - electrical problem) , myopathies and myocardial infarction/ heart attack (reduced blood supply to heart)
55
KCl is also an irritant - what are the implications of this?
There is a risk of extravasation essp when administered TOO fast
56
What are the complications of extravasation?
- may cause tissue necrosis - px may need plastic surgery or limb amputation
57
If a patient is HYPOKALEMIC - how do we manage them?
- โŒ we **DO NOT RX K+SUPPLEMENTATION!!** instead we must : - 1๏ธโƒฃ check the Mg levels - assess if they are low or normal - Mg levels are important for K+ reabsorption - 2๏ธโƒฃ if low - we must correct Mg levels FIRST as they are linked and K+ levels will not increase unless Mg levels are corrected