CV Tumors Flashcards Preview

Cardiovascular > CV Tumors > Flashcards

Flashcards in CV Tumors Deck (23):
1

Most Heart tumors are...?

Metastases, not primary; lung, melanoma, breast, leukemia, lymphoma

2

What are the most primary heart neoplasms

Myxoma
Rhabdomyoma

3

What is the histology of myxoma

Myxoma cells embedded in abundant ground substance

4

What is carney syndrome

AD or AR disorder

Multiple myxomas - skin, heart, breast, etc

Spotty pigemntation

Endocrine overactivity

5

What is rhabdomyoma associated with

Tuberous sclerosis

6

What is the histology of rhabdomyoma

spider cells - myocytes w/ vacuolations

7

Multiple firm, white nodules

Rhabdomyoma gross appearance

8

Other primary heart neoplasms

Lipomas - asymptomatic; ball-valve effect

Papillary fibroelastmas - on valves; can emobilize

Angiosarcomas

9

What are the benign vascular neoplasms

Hemangioma
Glomus tumor
lymphangioma
bacillary angiomatosis

10

What are the intermediate vascular neoplasms

Kaposi's
Hemangioendothelioma

11

What are the malignant vascular neoplasms

Angiosarcoma
Hemangiopericytoma

12

Types of hemangiomas

Strawberry/juvenile

Cherry/adult

Pyogenic granulomas

Cavernous hemangioma

13

What are pyogenic granulomas

hemangiomas that can bleed r ulcerate; seen w/ pregnancy or trauma

14

What are cystic hygromas

cavernous lymphangiomas; neck/axilla; infants/children; blood vessels devoid of blood

Seen in Turner syndrome

15

What causes bacillary angiomatosis

Bartonella infection - HIF-1 secretion leading to capillary proliferation

16

Types of Kaposi's Sarcoma

Chronic - classic type; multiple red to purple skin nodules

Lymphadenopathic - African; very aggressive

Transplant - localized or widely metastatic; may not have cutanous lesions

AIDS-associated

17

Which virus is associated w/ Kaposi's sarcoma

HHV-8; found in 95% of lesions

18

Morphology of Kaposi's

spindle cells

19

Treatment of Kaposi

Resection/cryotherapy
Radiation
Chemotherapy
If related to immunosuprression; decrease suppression, angiogenesis inhibitors

20

Causes of angiosarcoma

Liver - arsenic, polyvinyl chlorid, thorotrast

Post-radial mastectomy

Post radiation

21

Angiosarcoma histology

Well differentiated - vascular channels

Less differentiated - spindle cells

22

Angiosarcoma prognosis

Poor - 5 year survival is 30%

23

Causes of lymphangiosarcoma

Radical mastectomy

Setting of lymphatic obstruction