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Flashcards in CYCLOPLEGICS Deck (78)
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1

Catecholamines

Hormones including:
DOPAMINE
EPINEPHRINE
NORE-PINEPHRINE

2

COMT

Catechol-o-methyl Transferase
-an enzyme of catecholamine metabolism

3

MAO

An enzyme of catecholamine metabolism

4

CYCLOPLEGIA

Paralysis of the ciliary body musculature responsible for accommodation

5

What is ANAPHYLAXIS

- Acute, systemic allergic hypersensitivity reaction to a previously sensitized allergen

6

EPI-PEN

Serious anaphylactic reactions develop within minutes (up to 2 hours) and require immediate emergency treatment with epinephrine

7

what are the dosage of EPIPEN ?

EpiPen 0.3mg
EpiPen Jr 0.15mg
Pregnancy category C

8

what diseases should you be cautious wit EPI-PEN

Caution in patients with heart disease or high blood pressure, Parkinson's disease, diabetes, or a thyroid disorder

9

FIGHT OR FLIGHT

Regulated by the SYMPATHETIC or ADRENERGIC branch of the autonomic nervous system

10

REST AND DIGEST

Regulated by the PARASYMPETHETIC or CHOLINERGIC branch of the autonomic nervous system

11

Nicotininc Receptors are located in the ANS HOW?

using postganglionic in the ANS and terminally located in the somatic nervous system

12

Muscarinic receptors are associated with?

Terminal organs of postganglionic nerves in the cholinergic system

13

Norepinephrine (NE) are used?

NT used in sympathetic adrenergic system and its target receptors are ALPHA AND BETA

14

Presynaptic FOUND IN THE SYMPATHETIC PHARMACOLOGY

+α2 inhibition of signal propagation

15

VASCULAR

+α1 vasoconstriction; +β2 vasodilation

16

RESPIRATORY

+β2 bronchodilation

17

CARDIAC

+β1 ↑ contractility & conduction

18

HEPATIC

+β2 glucogenolysis

19

PANCREATIC

+β2 ↑ insulin release;
+α2 ↓ insulin release

20

IRIS

+α1 mydriasis

21

Ciliary BODY

+β2 relaxation & ↑ aqueous production
-β2 or +α2 ↓ aqueous production

22

What is Relative receptor Activity?

Epinephrine Vs Norepinephrine

23

when it comes to Alpha 1

Norepeinephrine (NE) - Neurogenic
it is NE> E (epinephrine)

24

What it comes to alpha 2

Epinephrine (greater than equal) to NE

25

When it comes beta 1

Epinephrine (equals) to NE

26

when it comes to beta 2?

epinephrine

27

What are ocular adrenergic Effects on Mydriasis?

- Increase interpalpebral aperture (Müeller’s muscle)
- Modulate aqueous generation
- Receptors in lateral rectus modulate vascular tone
- Receptors in trabeculum & Schlemm’s canal suppress accommodation

28

What is the standard care for all new patients when it comes do dilation?

Last to be performed in exam sequence
Bilateral under most every circumstance

29

What should be used to estimate the ocular angle?

Gonioscopy > Van Herick > shadow test
Commonly large in myopes and aphakes

30

what are the factors that affect when it comes to reduced sensitivity?

Age-related miosis
Unstable diabetes
Post-op pupils
Posterior synechiae
Dark irides
Pseudoexfoliation Syndrome