CYP Inducers, Substrates and Inhibitors Flashcards

1
Q

Carbamazepine

A

inducer

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2
Q

Chronic alcohol abuse

A

inducer

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3
Q

Griseofulvin

A

inducer

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4
Q

Modafinil

A

Inducers

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5
Q

Nevirapine

A

inducer

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6
Q

Phenobarbital

A

inducer

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7
Q

Phenytoin

A

inducer

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8
Q

Rifampin

A

inducer

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9
Q

St. John’s wart

A

inducer

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10
Q

Antiepileptics

A

substrate (preparatory molecules)

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11
Q

oral contraceptives

A

substrates (preparatory molecules)

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12
Q

theophylline

A

substrates (preparatory molecules)

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13
Q

warfarin

A

substrates (preparatory molecules)

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14
Q

Acute alcohol use

A

inhibitor

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15
Q

amiodarone

A

inhibitor

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16
Q

chloramphenicol

A

inhibitor

17
Q

cimetidine

A

inhibitors

18
Q

ciprofloxacin

A

inhibitor

19
Q

erythromycin/clarithromycin

A

inhibitor

20
Q

grapefruit juice

A

inhibitor

21
Q

isoniazid

A

ihibitor

22
Q

ketoconazole

A

inhibitor

23
Q

metronidazole

A

inhibitor

24
Q

ritonavir

A

inhibitor

25
Q

sodium valproate

A

inhibitor

26
Q

sulfonamides

A

inhibitor

27
Q

inhibitor

A

decrease metabolism

28
Q

substrate

A

preparatory molecules

29
Q

inducers

A

increased metabolism