CYP P450, Sulfas, antidotes Flashcards by Stephanie Escobar

Q

Sodium valproate

A

CYP–P450 Inhibitor

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Q

Isoniazid

A

CYP–P450 Inhibitor

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Q

Grape fruit juice

A

CYP–P450 Inhibitor

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Q

Ritonavir

A

CYP–P450 Inhibitor

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Q

Amiodarone

A

CYP–P450 Inhibitor

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Q

Metronidazole

A

CYP–P450 Inhibitor

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Q

Omeprazole

A

CYP–P450 Inhibitor

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Q

Ciprofloxacin

A

CYP–P450 Inhibitor

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Q

Sulfonamides

A

CYP–P450 Inhibitor

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Q

Ketoconazole

A

CYP–P450 Inhibitor

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Q

Fluconazole

A

CYP–P450 Inhibitor

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Q

Acute alcohol abuse

A

CYP–P450 Inhibitor

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Q

Chloramphenicol

A

CYP–P450 Inhibitor

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Q

Erythromycin/clarithromycin

A

CYP–P450 Inhibitor

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Q

Cimetidine

A

CYP–P450 Inhibitor

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Q

Chronic alcohol use

A

CYP–P450 Inducer

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Q

Modafinil

A

CYP–P450 Inducer

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Q

St. John’s wort

A

CYP–P450 Inducer

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Q

Phenytoin

A

CYP–P450 Inducer

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Q

Phenobarbital

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A

CYP–P450 Inducer

Q

Nevirapine

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A

CYP–P450 Inducer

Q

Rifampin

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A

CYP–P450 Inducer

Q

Griseofulvin

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A

CYP–P450 Inducer

Q

Carbamazepine

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A

CYP–P450 Inducer

Sulfonamide antibiotics

Sulfa Drug

Sulfasalazine

Sulfa Drug

Probenecid

Sulfa Drug

Furosemide

Sulfa Drug

Acetazolamide

Sulfa Drug

Celecoxib

Sulfa Drug

Thiazides

Sulfa Drug

Sulfonyl ureas

Sulfa Drug

Cyanide antidote

Hydroxocobalamin Nitrites + Sodium Thiosulfate

Heparin antidote

Protamine sulfate

Lead antidote

Penicillamine Dimercaprol Succimer Calcium disodium EDTA

Digoxin (Digitalis) antidote

Digoxin specific antibody fragments

Copper antidote

Penicillamine | Trientine

Antimuscarinic/ Anticholinergic antidotes

Physostigmine (Crosses BBB) | Control hyperthermia

AChE inhibitors, Organophosphate antidotes

Atropine > Pralidoxime

Beta Blocker antidote

Atropine Glucagon Saline

Carbon Monoxide antidote

100% O2 | Hyperbaric O2

Methanol, Ethylene Glycol (Anti-freeze) antidote

Fomepizole > ethanol + dialysis

Methemoglobin antidote

Methylene Blue | Vitamin C

Salicylate antidote

Sodium Bicarbonate (alkalinize urine), dialysis

TCAs antidote

Sodium Bicarbonate (stabilizes cardiac cell membrane)

Acetaminophen antidote

N-Acetylcysteine ( replenishes glutathione)

Benzodiazepine antidote

Flumazenil

Arsenic & Mercury antidote

Dimercaprol | Succimer

Iron antidote

Deferoxamine Deferiprone Deferasirox