Flashcards in Cystic Fibrosis Deck (39):
HyperSal does what?
Hydrates airways mucus secretions
Inhaled antibiotics are used for what in CF?
Treatment and prevention of lung and sinus infections
Oral azithromycin does what for CF?
Reduces airway inflammation
Disrupts P. aeruginosa biofilm
What kind of diet is needed in CF pts?
PPI use in CF treatment does what?
Prevents degradation of pancreatic enzymes in stomach
What are most common organisms found in CF infections?
Give how many abx if CF infection with p. aeruginosa?
2 for synergy
What is used to eradicate p. aeruginosa from the lungs?
Give what two things prior to inhaled abx?
Bronchodilator and or mucolytic
What are the two inhaled abx used in CF?
Tobramycin and aztreonam
What are the 2 name brands of tobramycin inhalation?
TOBI is used in what ages?
6 or older
Take TOBI doses how far apart?
TOBI podhaler capsules should be stored how?
Room temp in dry place
What is aztreonam lysine inhalation solution name brand?
Cayston is for what ages?
7 and older
Doses of Cayston should be how far apart?
Give Cayston how long after reconstitution?
Use a new TOBI podhaler device how often?
What agents promote mucus clearance?
Store Pulmozyme ampules where?
Do not expose pulmozyme to room temperature for how long?
24 or more hours
Do not mix pulmozyme with what?
Any other drug in nebulizer
What is recommended order for CF treatment?
What three enzymes are in PEPs?
Dose of PEP products is based on which complement?
Dose adjust PEP products how often?
Until what occurs?
Stools are normalized
Do not exceed what amount of lipase/kg/meal?
Colonic stricture risk
What kind of meals require higher doses of PEP?
High fat content
Can sprinkle PEP beads on what kind of food?
Can't be chewed
Don't mix PEP beads with what based foods?
Take PEP at the beginning of each meal with what?
Generous amount of non caffeinated liquid
Retention of PEP in mouth before swallowing causes what?
Keep PEP products in what?
What formulation of PEP requires a PPI because it's not enteric coated?
Increasing time the CFTR channels remain open
Augmenting chloride transport activity
What is the requirement of using Ivacaftor?
Mutation is CFTR gene
What is ivacaftor name brand?