Cystic fibrosis, SCID

Question 1

What is the syndrome of Cystic Fibrosis ?

Answer 1

Cells of bronchi produce thick, sticky mucus that clogs the respiratory tract.

Question 2

Is the gene therapy for Cystic fibrosis in vivo or ex vivo ?

Answer 2

In vivo

Question 3

What vector is used in gene therapy for Cystic Fibrosis ?

Answer 3

Hollow lipid spheres

Question 4

How can the lipid sphere be transferred to the patient ?

Answer 4

They are inhaled by the patient through aerosol spray.

Question 5

What can the lipid sphere do ?

Answer 5

Fuse with cell membrane of the cells of trachea and bronchi.

Question 6

What cause SCID ?

Answer 6

Lack of enzymes that involved in the development of certain types of WBC which are responsible for immunity

Question 7

is the gene therapy for SCID in vivo or ex vivo ?

Answer 7

ex vivo

Question 8

What vector is used for gene therapy for SCID ?

Answer 8

Virus.

Question 9

What is the target cell of SCID gene therapy ?

Answer 9

Stem cells.

Question 10

Where can we extract the target cell for SCID gene therapy ?

Answer 10

Bone marrow.

Question 11

What can virus do as a vector ?

Answer 11

Carry out infection.