CYTOGENETICS LIMITATIONS AND ADVANTAGES

Question 1

What are the limitations of cytogenetics?

Answer 1

Viable cells, depend on cell growth, very laborious, scarce skill, long turn around time, resolution limited to 10 Megabase, no genes information

These limitations affect the practical application of cytogenetic techniques in clinical settings.

Question 2

What is a key advantage of cytogenetics?

Answer 2

Complete representation of the tumor genome

This allows for a comprehensive understanding of the genetic alterations present in tumors.

Question 3

What specific information does cytogenetics provide?

Answer 3

Shows copy number, translocations, and complex markers

This information is crucial for diagnosing and understanding various cancers.

Question 4

Fill in the blank: The resolution of cytogenetics is limited to _______.

Answer 4

10 Megabase

Question 5

True or False: Cytogenetics requires a high level of skill and is considered laborious.

Answer 5

True

Question 6

What does the dependence on cell growth indicate in cytogenetics?

Answer 6

It indicates that cytogenetic analysis can only be performed on actively dividing cells

This can limit the types of samples that can be analyzed.