Cytokines Flashcards
(7 cards)
1
Q
IL-2
A
action: Tcell proliferation; regulatory Tcell survival
source: activated Tcells
2
Q
IFN- gamma
A
action: activation of macrophages
source: CD4+ and CD8+ T cells, natural killer cells
3
Q
IL-4
A
action: B cell switching to IgE
source: CD4 Tcells, mast cells
4
Q
IL-5
A
action: activation of eosinophils
source: CD4+ Tcells, mast cells, innate lymphoid cells
5
Q
IL-17
A
action: stimulation of acute inflammation
source: CD4+ Tcells, other cells
6
Q
IL-22
A
action: maintenance of epithelial barrier function
source: CD4+ Tcells, natural killer cells, innate lymphoid organs
7
Q
TGF-beta
A
action: inhibition of T cell activation, differentiation of regulatory T cells
source: CD4+ T cells; many other cells