Cytokines Flashcards

(7 cards)

1
Q

IL-2

A

action: Tcell proliferation; regulatory Tcell survival
source: activated Tcells

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2
Q

IFN- gamma

A

action: activation of macrophages
source: CD4+ and CD8+ T cells, natural killer cells

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3
Q

IL-4

A

action: B cell switching to IgE
source: CD4 Tcells, mast cells

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4
Q

IL-5

A

action: activation of eosinophils
source: CD4+ Tcells, mast cells, innate lymphoid cells

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5
Q

IL-17

A

action: stimulation of acute inflammation
source: CD4+ Tcells, other cells

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6
Q

IL-22

A

action: maintenance of epithelial barrier function
source: CD4+ Tcells, natural killer cells, innate lymphoid organs

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7
Q

TGF-beta

A

action: inhibition of T cell activation, differentiation of regulatory T cells
source: CD4+ T cells; many other cells

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