Cytomegalovirus Flashcards

1
Q

Da infección:

A

Vertical más frecuente

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2
Q

Causa infecciosa más común de:

A

Anormalidades congénitas

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3
Q

Da dos tipos de infecciones

A

Latentes y persistentes

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4
Q

Se disemina por medio de:

A

Linfocitos y leucocitos

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5
Q

Se reactiva por:

A

Inmunodepresión

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6
Q

Se controla por:

A

Inmunidad celular

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7
Q

La mayoría de las veces los pacientes se presentan:

A

Asintomáticos

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8
Q

Se identifica en:

A

La mayoría de tejidos y fluidos

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9
Q

En adultos

A

Aintomático
Mono-like
Hepatitis
ETS*

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10
Q

Pacientes inmunosuprimidos y post-trasplantados

A
Neumonía
Retinitis 
Colitis 
Esofagitis
EICH (inserto contra el huesped)
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11
Q

CMV congénito:

A

Primoinfección materna, 90% asintomáticos al nacer

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12
Q

Síntomas de CMV congénito:

A

Peso bajo, trombocitopenia, microcefalia, sordera, retraso psicomotor, calcificaciones periventriculares, ictericia, hepatoesplenomegalia, exantema

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13
Q

“Blueberri muffin baby” se da por:

A

Hematopoyesis extramedular

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14
Q

“Blueberri muffin baby” la infección hará más dao si pasa en el:

A

Primer trimestre

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15
Q

“Blueberri muffin baby” es más frecuente que pase durante el:

A

Parto

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16
Q

Diagnóstico

A

Histológico: células citomegálicas (ojos de lechuza)
Serología (IgM e IgG)
PCR (sangre, orina, semen)

17
Q

Tratamiento

A

Ganciclovir y valganciclovir; cidofovir y foscarnet

Toxicidad del tratamiento