D2L Quizzes Ch. 12

Question 1

What would happen if mitochondria retreated with a proton gradient and coupler, such as 2,4-dinitrophenol?

Answer 1

Protons will be pumped by the mitochondrial electron transport chain, although no ATP would be synthesized

Question 2

What structural component of the yeast ATP synthase synthesize ATP?

Answer 2

The head piece containing 3 alpha and 3 beta subunits

Question 3

What is the difference in the number of ATP generated per cytosolic NADH oxidized by the malate aspartate shuttle as compared to the glycerol 3P shuttle?

Answer 3

1 ATP

Question 4

Which one of the following statements about the glycerol phosphate shuttle is true?

Answer 4

It involves the transfer of electrons from cytoplasmic NADH to dihydroxyacetone phosphate to yields glycerol phosphate 

Question 5

What would happen to a mutated ATP synthase enzyme, where the proton binding aspartate residue on the C subunits was mutated to a lysine?

Answer 5

The enzyme would make ATP without the need for a proton gradient

Question 6

An ATP synthase enzyme with more than 10 carbon subunits in the F0 stalk would:

Answer 6

Require more protons to complete one 360° rotation

Question 7

Maybe mitochondrial disease or passed on from parents to offspring

Answer 7

Through the mother only

Question 8

Where is the alpha subunit became a subunit and the better subunit in the yeast ATP synthase complexes?

Answer 8

The alpha subunit is in the stator, the beta subunit is in the rotor, and the gamma subunit is in the head piece

Question 9

How many ATP’s are obtained from one acetyl CoA run once through the citrate cycle, assuming that all resulting NADH and FADH2 is used by the electron transport chain and oxidative phosphorylation to make ATP?

Answer 9

10

Question 10

The mitochondrial ATP/ADP translocase is what type of transporter

Answer 10

Antiporter

Question 11

Which one of the following correctly designates the number of ATP generated by the reducing molecule shown?

Answer 11

FADH2 from the citrate cycle = 1.5 ATP

Question 12

What experimental observation, best explains the bio chemical reason for the currency exchange ratio being 5 ATP/2 NADH in mitochondrial oxidative phosphorylation?

Answer 12

The number of H+ translocated across the inner mitochondrial membrane for each NADH oxidized, was determined, and then divided by the number of H+ required to synthesize each ATP and transport in a Pi for each ATP generated

Question 13

The drug oligomycin inhibits ATP synthase by preventing protons from flowing through the enzyme. Oligomycin must bind to the _______ of ATP synthase

Answer 13

F0 subunit