SW Ch. 12

Question 1

According to the binding change mechanism, how many protons pass through the F0 subunit with every 120° turn, and how many ATPs are synthesized by the ATP synthase complex for every 360° turn?

Answer 1

3,3

Question 2

How would a mutation of Asp59 in the sea subunit to Lys affect the function of the ATP synthase complex?

Answer 2

The sea subunit would be unable to except a proton from the a subunit half-channel, and the gamma subunit would not be able to rotate, rendering the complex nonfunctional

Question 3

What components are in the stator subunit of the ATP synthase complex?

Answer 3

A, B, D, H, OSCP

Question 4

What components are in the rotor subunit of the ATP synthase complex

Answer 4

Gamma, C, epsilon, delta

Question 5

What components are in the headpiece subunit of the ATP synthase complex?

Answer 5

Alpha and beta

Question 6

Which enzyme is crucial for transfer of electrons from cytosolic NADH into the mitochondrial matrix in muscle cells?

Answer 6

Glycerol-3-P dehydrogenase

Question 7

Which of the following subunits rotates in response to the flow of protons through F0?

Answer 7

y (gamma)

Question 8

In what order would malate-aspartate shuttle enzymes need to function in order to facilitate transfer of an electron pair from the cytosol to the mitochondrial matrix in liver cells?

Answer 8

1. Cytosolic malate dehydrogenase 2. Mitochondrial malate dehydrogenase 3. Mitochondrial aspartate aminotransferase 4. Cytosolic aspartate aminotransferase