D4

Question 1

Actinic keratosis lesions?

Answer 1

Scaly
Papular/plaque
Surrounding skine show sign of solar damage(Telangiectasia and hyperpigmentation)

Question 2

The common area affected?

Answer 2

Face
Scalp
Lateral neck
Dorsal surface of the hand

Question 3

Progression?

Answer 3

May progress to SCC in some patient

Question 4

managment?

Answer 4

Small: Cryotherapy(liquid nitrogen)
Large: Fluorouracil

Question 5

Indication for biopsy?

Answer 5

Size >1 cm
Ulceration
Induration
Failure of drug therapy

Question 6

Molluscum contagiousum etiology?

Answer 6

Poxvirus

Question 7

Lesion?

Answer 7

Papule
Central umbilication
Surrounding pruritis
Involve all body parts except palm and sole

Question 8

Risk?

Answer 8

Skin to skin contact

HIV(discriminate)

Question 9

Treatment of acne vulgaris?

Answer 9

Depend on type

Question 10

Comedonal acne?

Answer 10

Close or open comedones in forehead, nose, and chine

May progress to inflamatory pustule/nodule

Question 11

Treatment?

Answer 11

Topical retinoid
Biologic agent(Salicylic,azelaic or glycolic acide)

Question 12

Inflammatory acne?

Answer 12

Inflamed papule/pustule;erythema

Question 13

Managment?

Answer 13

Mild: Retinoid + Benzoil peroxidase
Moderate: Add topical Ab(clindamycin, erythromycin)
Sever: Add oral antibiotic(Tetracycline)

Question 14

Nodular(cystic) acne?

Answer 14

Nodule
Cyst
May form sare or sinus

Question 15

Tx?

Answer 15

M: Topical retinoid + benzoyl peroxidase + topical ab
S: Add oral antibiotic(Tetracycline)
Unresponsive: oral isotretinoin

Question 16

cause for acne?

Answer 16

hyperkeratinization
Increase sebum production
P.Acne colonization

Question 17

Indication for oral Ab in acne?

Answer 17

Sever inflammatory and nodulocystic acne
Widspread involvment(Back and upper shoulder)
failure of adding topical Ab in Moderate I/ND acne

Question 18

Treatment of MC?

Answer 18

curritage
Cryotherapy
Topical agent(podophylotoxine)

Question 19

Dermatitis herpetiformis (DH)?

Answer 19

rare
chronic, autoimmune skin condition
characterized by the presence of groups of severely itchy blisters and raised red skin lesions.

Question 20

These are most commonly located on the?

Answer 20

elbows
knees
buttocks
lower back 
scalp.

Question 21

Can you have dermatitis herpetiformis without celiac disease?

Answer 21

Dermatitis herpetiformis patients usually don’t have the digestive symptoms that go along with celiac disease.
Almost all patients with dermatitis herpetiformis have celiac disease, though the disease is asymptomatic (they have no gastrointestinal symptoms).

Question 22

Dermatitis herpetiformis is treatement?

Answer 22

gluten-free diet and an oral antibiotic called dapsone.. If dapsone doesn’t help, prescribe sulfapyridine or sulfasalazine.

Question 23

Necrobiosis lipoidica diabeticorum (“NLD”) ?

Answer 23

is a rash that occurs on the lower legs. It is more common in women, and there are usually several spots. They are slightly raised shiny red-brown patches. The centers are often yellowish and may develop open sores that are slow to heal.

Question 24

Discoid lupus lesions?

Answer 24

often red, scaly, and thick.
Usually they do not hurt or itch.
Over time, these lesions can produce scarring and skin discoloration (darkly colored and/or lightly colored areas).

Question 25

Lesions most often appear?

Answer 25

on the face, ears, scalp, neck, and hands

Question 26

Herptic witlow?

Answer 26

HSV infection of hand | virus enter on skin defect after contact

Question 27

Lesion?

Answer 27

``` Prodrome symptom(fever..) Grouped Vesicular rash on erythemetous base Tingling Pain Burning ```

Question 28

managment?

Answer 28

self resolve | acyclovir in immunocompromized

Question 29

Senile/actnenic/solar purpura cause?

Answer 29

Loss of elastic fiber in perivasculas spese--rapture of vesseles during skine streching

Question 30

CM?

Answer 30

Common in older Minley affect posterior forarm and hand Echemosis Hemosidrosis in skine(Hyperpigmentation/brown discoloration of akin)

Question 31

Insidence and severity common in?

Answer 31

Anticoagulation NSAID Corticosteroid

Question 32

Macular skin lesion in NF and TS?

Answer 32

NF:Cafe-au-lait spote/hyperpigmented) TS:Ash-leaf spote/Hypopigmented/

Question 33

Lichens panus oral lesion?

Answer 33

``` White papule/plaque Lesion conected by white lacy lesion(Wickham stria) Mucosal athtophy Ulcer Erythema Can present w/o skine involvment ```

Question 34

Pathophysiology of Lichen planus?

Answer 34

CD8 reaxn after triger(Infn,Drug and allergen) exposure

Question 35

Telogen effluvium CM?

Answer 35

Acte, diffiuse, non-inflamatory hair loss Scalp and hair fibers apear normal Hair shaft easily pulled out(>10-15 % once) MCC of hair loss in adult

Question 36

Triggers?

Answer 36

``` Sever illness, fever, and surgery Pregnancy, child birth Emotional stress Endocrine and nutritional problem Wight loss ```

Question 37

Pathophysiology?

Answer 37

Most of follicles pass to rest/sheding phase

Question 38

Normal hair follicle stage?

Answer 38

``` Growth phase(90%)--anagen Transformation phase(<1%)--catagon rest/sheding phase(<10%)--telogen ```

Question 39

managment?

Answer 39

Reasurance/self limited/ | Tx underlining cause

Question 40

Achantosis nigrican Cxs and ass.disease?

Answer 40

Benign: Insulin resistance(DM,PCOS) Malignant:GU and GI malignancy(rapid onset and can affect unesual are like MM,palm and sole)

Question 41

Caracterstich?

Answer 41

Hyperkeratotic and hyperpigmented plaque It typically affects the armpits, groin and neck. Valvely texture

Question 42

Addison disease associated skine condition?

Answer 42

Generalized hyperpigmentation(area friction(knee,elboe..) and sun light exposure area(and,face,,)

Question 43

Bullous pemphigoid CM?

Answer 43

``` Sever pruritis Bullea Erythematous base Prodrome(Urticarial and eczematous lesion) Mucosal involvment in some pt ```

Question 44

Associated disease?

Answer 44

Age >65 Malignancy Nurologic disease(PD,MS...)

Question 45

Pathophisiology?

Answer 45

IgG Ab against hemidesmosome | IgG and C3 deposition in DE junction

Question 46

Managment?

Answer 46

Topical potent CS(Clobetasole..)--effective | Systemic CS not recomended

Question 47

Biopsy in dermatitis herpitiformis?

Answer 47

Microabsces in dermal papilla | IgA deposition in dermis

Question 48

When Tinea corporis lesion confluent they form?

Answer 48

Flower petal lesion

Question 49

SCC in situ CM?

Answer 49

slow growing red scaly patch/plaque

Question 50

Treatment of type 1 drug rxn?

Answer 50

discontinu drug mild: antihistamin sever: Im GC and Epiniphrine

Question 51

smptome in mild case?

Answer 51

Urticaria Pruritis Flushing

Question 52

Sever?

Answer 52

Anaphylaxis | Angioedema of larynex