Data interpretation: Hypertension & blood pressure readings Flashcards

(63 cards)

1
Q

What are the 3 stages of hypertension?

A

Stage 1 hypertension

Stage 2 hypertension

Stage 3 hypertension

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2
Q

To diagnose hypertension, what are the 2 ways in which a patient must measure their blood pressure?

A

Clinic blood pressure: Their blood pressure is measured by a nurse or doctor during an appointment

AND ——————————————————

Ambulatory blood pressure monitoring: Patient measures blood pressure throughout the day and night, during normal activities, using a portable device

OR

Home blood pressure monitoring: Patient measures blood pressure at home over a period of days or weeks, usually at specific times, while seated and resting

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3
Q

How do you explain to a patient what hypertension is?

A

Blood pressure is the force of your blood pushing against the artery walls, which are the tubes in the body that transport blood

If the blood pressure is too high, this is called hypertension

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4
Q

How do you explain to a patient what the 2 main types of hypertension are?

A

The 2 types are essential hypertension and secondary hypertension

Essential hypertension is when your high blood pressure isn’t due to any identifiable cause

Secondary hypertension is when your high blood pressure has occurred as a result of another condition

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5
Q

How would you explain to a patient what the risk factors are for essential hypertension?

A

There are some major risk factors that can lead to essential hypertension:

Increasing age

Lack of exercise

Smoking

Unhealthy diet with lots of salt

Obesity

High alcohol intake

Genetics, if other family members also have high blood pressure

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6
Q

How would you explain to a patient what the causes are for secondary hypertension?
RRENALSS

A

There are several conditions that can cause high blood pressure, for example:

R: Renal conditions such as glomerulonephritis, renal artery stenosis

R: RBCs: Polycythemia

E: Endocrine/hormonal conditions such as Cushing’s syndrome, Conn’s syndrome, pheocromocytoma, diabetes AND drugs that affect hormone levels such as OCP, NSAIDs, alcohol, steroids

N: Conditions originating from the nervous system eg. Raised intracranial pressure

A: Aortic coarctation (narrowed aorta)

L: little people: Pregnancy-induced high BP

S: Stress eg. Trauma, white-coat hypertension

S: Sleep apnea

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7
Q

How do you explain to a patient how their clinic BP is measured?

A

A doctor or nurse will measure their blood pressure manually using an arm cuff

  1. If the first BP reading suggests hypertension, they will take a second BP reading to confirm
  2. If the second BP reading is quite different from the 1st, then they will take a 3rd reading and use the lowest of the 2nd and 3rd readings
  3. They will measure the BP in both arms, and if there is more than a 15 mmHg difference the doctor will measure both arms again. Highest BP arm is used for diagnosis
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8
Q

How do you explain to patient why ABPM or HBPM is also needed to diagnose hypertension?

A

Some people can get white-coat syndrome during their appointment to measure BP: Being in a medical setting makes you anxious, which will increase your blood pressure

For ABPM or HBPM, it is measured at home by the patient themselves or by an automatic monitor, so the readings will not be affected by white-coat syndrome

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9
Q

How do you explain to a patient how ABPM is measured?

A
  1. ABPM comes with arm cuff and monitor, which the patient needs to wear for 24 hours (the monitor is on a belt)
  2. ABPM will take daytime readings every 30 minutes and nighttime readings every 60 minutes
  3. ABPM will make a sound before it takes a reading: Make sure you are sitting with legs uncrossed/standing supported then keep arm below heart level. Don’t talk or move during measurement
  4. Avoid showers and baths during 24 hours period so that ABPM doesn’t get wet
  5. Driving not recommended
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10
Q

How do you explain to a patient how HBPM is measured?

A
  1. Take 2 readings each one minute apart. Do this in the morning before breakfast and repeat process in the evening before bed: Overall should take 4 readings in one day
  2. Continue so that you have readings for at least 4 days, ideally 7 days
  3. Make sure you are sitting with legs uncrossed, arm at heart level, don’t talk or move
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11
Q

What 2 criteria must be fulfilled to diagnose stage 1 hypertension?

A

Clinic BP from 140/90 to 159/99 mmHg

ABPM/HBPM from 135/85 to 150/95 mmHg

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12
Q

What 2 criteria must be fulfilled to diagnose stage 2 hypertension?

A

Clinic BP from 160/100 to 180/120 mmHg

ABPM/HBPM is 150/95 mmHg or higher

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13
Q

What 2 criteria must be fulfilled to diagnose stage 3 hypertension?

A

Clinic systolic BP higher than 180 mmHg

Clinic diastolic BP higher than 120 mmHg

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14
Q

How do you work out the blood pressure from ABPM readings?

A

Use the average value of at least 14 measurements taken during the person’s usual waking hours to confirm a diagnosis of hypertension

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15
Q

How do you work out the blood pressure from HBPM readings?

A

Discard the measurements taken on the first day and use the average value of all the remaining measurements to confirm a diagnosis of hypertension

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16
Q

How do you work out the blood pressure from clinic readings?

A

Take a second measurement during the consultation.

If the second measurement is substantially different from the first, take a third measurement.

Record the lower of the last 2 measurements as the clinic blood pressure.

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17
Q

If a patient has a clinic BP in the range 140/90-179/119, what are the 3 next steps in management?

A
  1. ABPM, if this is unsuitable then HBPM
  2. Investigate target organ damage
  3. Calculate QRISK3 score
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18
Q

How do you explain what is meant by target organ damage by hypertension?

A

Changes in structure or function of organs due to damage from high blood pressure

The 4 main target organs are heart, brain, kidneys and eyes

Target organ damage can increase risk of cardiovascular events such as stroke, heart failure, kidney disease

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19
Q

Which initial investigation is done to confirm target organ damage to the heart, by hypertension?

A

12-lead ECG

To look for left ventricular hypertrophy

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20
Q

Which initial investigation is done to confirm target organ damage to the eyes, by hypertension?

A

Fundoscopy

To look for hypertensive retinopathy

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21
Q

Which initial investigation is done to confirm target organ damage to the brain, by hypertension?

A

Blood tests: HbA1c, U&Es, serum cholesterol and HDL

To look for diabetes and atherosclerosis

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22
Q

Which initial investigation is done to confirm organ damage to the kidneys, by hypertension?

A

Urinalysis: Urine dip stick and urine albumin: creatinine ratio

To check for hematuria and proteinuria (signs of CKD)

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23
Q

How do you explain to a patient what QRISK3 is?

A

A scoring tool used to estimate a person’s risk of developing a heart attack or stroke (CVD event) over the next 10 years

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24
Q

If a patient has clinic BP that suggests stage 3 hypertension and is asymptomatic, what is the initial management?

A

Initial investigations for target organ damage

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25
If an asymptomatic patient with clinic BP stage 3 hypertension has target organ damage, when should you offer treatment?
Immediately treat Don't need to take ABPM/HBPM to confirm diagnosis first
26
If an asymptomatic patient with clinic BP stage 3 hypertension has no target organ damage, when should you offer treatment?
Repeat clinic BP readings within 7 days to confirm stage 3 hypertension Doesn't need immediate treatment
27
If a patient has clinic BP that suggests stage 3 hypertension, in which 3 situations should you do a same-day referral to cardiology?
1. It is accelerated/malignant hypertension 2. It is due to suspected phaeochromocytoma 3. Patient presents with life-threatening features
28
How do you explain to a patient what accelerated/malignant hypertension is?
Very high blood pressure (180/120 or higher) that comes on suddenly and quickly An emergency that needs to be urgently treated by cardiologist
29
What are the 3 common signs of accelerated hypertension?
1. Severe increase in blood pressure to 180/120 mmHg or higher (and often over 220/120 mmHg) 2. Fundoscopy shows papilledema 3. Fundoscopy shows retinal haemorrhaging
30
How do you explain to a patient what phaeochromocytoma is?
Rare tumour of the adrenal glands, which sit above the kidneys
31
What are the 5 common signs of pheochromocytoma?
1. Fluctuating bp 2. Palpitations 3. Excessive sweating 4. Pallor 5. 'Attacks' of high bp, nervousness, tremors , excessive sweating occurring during stress or exercise
32
In which 3 situations should you make a routine cardiology referral for a patient with hypertension?
1. Patient under 40 yrs old 2. Suspected secondary hypertension 3. Patient is unresponsive to stage 4 therapy
33
If a patient has stage 2 hypertension, how should they be treated?
Antihypertensive drugs Lifestyle changes
34
If a patient has stage 1 hypertension and they are under 80 yrs old, and they have diabetes/CKD/target organ damage, how should they be treated?
Antihypertensive drugs Lifestyle changes
35
If a patient has stage 1 hypertension and they are under 80 yrs old, and their QRISK3 score is min. 10%, how should they be treated?
Antihypertensive drugs Lifestyle changes
36
If a patient has stage 1 hypertension and they are under 80 yrs old, and their QRISK3 score is less than 10%, how should they be treated?
Don't need antihypertensive drugs but can if patient wants Mainly lifestyle changes
37
If a patient has stage 1 hypertension and they are under 60 yrs old, and their QRISK3 score is less than 10%, how should they be treated?
Antihypertensive drugs Lifestyle changes
38
If a patient is less than 55 yrs old AND/OR diabetic, what is the first-line antihypertensive drug in step-up treatment?
ACE inhibitor or ARB (angiotensin receptor blocker)
39
If a patient is more than 55 yrs old AND/OR African/African Caribbean, what is the first-line antihypertensive drug in step-up treatment?
Calcium channel blocker
40
If a patient is less than 55 yrs old AND/OR diabetic, what is the second-line antihypertensive drug in step-up treatment?
Calcium channel blocker or thiazide-like diuretic Overall patient is now taking 2 drugs: ACE inhibitor/ARB and CCB/thiazide-like diuretic
41
If a patient is more than 55 yrs old AND/OR African/African Caribbean, what is the second -line antihypertensive drug in step-up treatment?
ACE inhibitor/ARB or thiazide-like diuretic Overall patient is now taking 2 drugs: CCB and ACE inhibitor/ARB/thiazide-like diuretic
42
What is the third-line antihypertensive drug in step-up treatment?
Add one that the patient is not already taking: ACE inhibitor/ARB, CCB or thiazide-like diuretic Overall patient is now taking 3 drugs: ACE inhibitor/ARB, CCB, thiazide-like diuretic
43
What is the 4th-line antihypertensive drug in step-up treatment, if the patient's potassium level is less than or equal to 4.5?
Spironolactone Overall patient is now taking 4 drugs: ACE inhibitor/ARB, CCB, thiazide-like diuretic, spironolactone
44
What is the 4th-line antihypertensive drug in step-up treatment, if the patient's potassium level is more than 4.5?
Alpha-blocker or beta blocker Overall patient is now taking 4 drugs: ACE inhibitor/ARB, CCB, thiazide-like diuretic, alpha/beta blocker
45
How do you explain to a patient what an ACE inhibitor is, and give examples?
A drug that stops the production of a molecule called angiotensin 2. Angiotensin 2 narrows blood vessels and blocks water retention in kidneys, these both increase BP. If angiotensin 2 isn't made, blood vessels remain wide and water is retained, which lower BP Lisinopril, ramipril
46
What are the 4 main side effects of ACE inhibitors?
Dry cough Dizziness Headaches Swelling in lips or tongue
47
How do you explain to a patient what an Angiotensin receptor blocker is, and give examples?
A drug that blocks angiotensin 2 and stops it from activating. Angiotensin 2 narrows blood vessels and causes water retention in kidneys, these both increase BP. If angiotensin 2 is blocked, blood vessels remain wide and less water is retained, which lower BP Losartan, candesartan, valsartan
48
What are the 5 main side effects of ARBs?
Dizziness Headaches Fatigue Nausea and vomiting Diarrhoea and constipation
49
How do you explain to a patient what an calcium channel blocker is, and give examples?
A drug that reduces the amount of calcium entering the heart and blood vessel cells. Calcium is needed for heart muscle and muscle in blood vessel walls to pump. By blocking calcium entry, the blood vessels will relax and widen Amlodipine, felodipine
50
What are the 3 main side effects of CCBs?
Ankle swelling Facial flushing Palpitations
51
How do you explain to a patient what an thiazide-like diuretic is, and give examples?
A drug that help the kidneys remove salt and water through the urine. This lowers the amount of fluid flowing through the veins and arteries. As a result, blood pressure goes down Indapamide
52
What are the 3 main side effects of thiazide-like diuretics?
Mild skin rash Dizziness Nausea or vomiting
53
How do you explain to a patient what spironolactone is?
A drug that blocks the action of aldosterone, a hormone that increases sodium retention and water retention, which increases BP
54
What are the 5 main side effects of spironolactone?
Gynecomastia: Unexpected breast tissue growth in males Irregular menstrual cycles or spotting Breast area tenderness Dizziness Headache
55
How do you explain to a patient what an alpha blocker is, and give examples?
A drug that stops a hormone called noradrenaline from tightening the muscles in the walls of smaller blood vessels. So the blood vessels remain open and relaxed Doxazosin, terazosin
56
What are the 5 main side effects of alpha blockers?
Dizziness Hypotension Sexual dysfunction Headaches Drowsiness
57
How do you explain to a patient what an beta blocker is, and give examples?
A drug that blocks the hormone adrenaline. Beta blockers cause the heart to beat more slowly and with less force. This lowers blood pressure Atenolol, bisoprolol, propanolol
58
What are the 5 main side effects of beta blockers?
Cold fingers or toes Difficulty sleeping or nightmares Sexual dysfunction Drowsiness and fatigue Dizziness
59
How can you confirm adrenal disorders as the cause of secondary hypertension?
Elevated aldosterone: Renin ratio Adrenal CT Can confirm Conn's syndrome, pheochromocytoma, bilateral adrenal hyperplasia
60
How can you confirm renal disorders as the cause of secondary hypertension?
24hr urine albumin: creatinine ratio Renal ultrasound CT/MRI renal angiogram
61
How can you confirm aortic coarctation as the cause of secondary hypertension?
CXR ECHO CT/MRI chest
62
How can you confirm Cushing's disease as the cause of secondary hypertension?
24hr cortisol excretion Dexamethasone suppression test
63
How can you confirm polycythemia as the cause of secondary hypertension?
FBC Blood film Bone marrow biopsy