Info-giving: Vascular Diseases Flashcards

(102 cards)

1
Q

Superficial thrombophlebitis
Varicose veins

A
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2
Q

How do you explain to a patient what peripheral arterial disease is?

A

Arteries are the tubes in the body that carry blood away from the heart and to the rest of the body, to deliver oxygen and nutrients. Peripheral arteries are the arteries that are further from the heart, and are located in arms and legs instead.

Peripheral arterial disease is a condition where the arteries to arms and legs are narrowed, reducing blood flow to those areas

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3
Q

How do you explain to a patient the underlying cause of peripheral arterial disease?

A

Arteries that supply blood to the arms and legs become narrowed, usually due to build up of fatty deposits on the inner lining of the artery. These deposits make it harder for blood to pass through.

As less blood travels to the arms and legs, they receive less oxygen and nutrients. The oxygen and nutrients are needed for the muscles, skin and other parts in the arms and legs to stay healthy.

Lack of oxygen n to these areas is what causes your signs and symptoms

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4
Q

How do you explain to a patient the risk factors for developing peripheral arterial disease? SMASH

A

These are the risk factors that can cause you to develop peripheral arterial disease?

S: Smoking

M: Metabolic conditions such as diabetes, high cholesterol, chronic kidney disease, heart diseases, high blood pressure

A: Age over 60, atherothrombosis

S: Stress

H: Hypothyroidism

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5
Q

How do you explain to a patient the symptoms of the claudication stage (stage II, Fontaine classification) of peripheral arterial disease?

A

Intermittent claudication: Pain in the legs due to peripheral arterial disease, that comes with activity and relieves with rest

Cramping/throbbing/burning pain in calf/thighs/buttocks

Pain occurs when doing an activity such as walking

Pain is relieved by resting legs, usually takes less then 10 minutes for pain to completely disappear

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6
Q

How to do you explain to a patient the symptoms of the asymptomatic stage (stage I, Fontaine classification) of peripheral arterial disease?

A

Patient has peripheral arterial disease but is not yet experiencing any symptoms

This is because even though the arteries in the arms and legs are narrowed, they are still wide enough for enough blood to reach these areas during any activities that you do

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7
Q

How do you explain to a patient how their intermittent claudication can further be classified, if they have stage 2 PAD?

A

Intermittent claudication is described as one of two types: Mild or moderate-severe claudication

Mild claudication: Cramping pain in legs occurs after walking more than 200 metres

Moderate-severe claudication: Cramping pain in legs occurs after walking less than 200 metres

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8
Q

How do you explain to a patient the symptoms of the rest pain stage (stage III, Fontaine classification) of peripheral arterial disease?

A

Severe, persistent burning pain in the legs, even when the person is not moving

So claudication does not disappear upon rest anymore

These symptoms start to occur when you develop chronic limb-threatening/critical ischaemia: It is a result of structures in the legs being starved of oxygen and nutrients for a long time, due to narrowed arteries

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9
Q

How do you explain to a patient the tissue loss stage (stage IV, Fontaine classification) of peripheral arterial disease?

A

This occurs when you have had chronic limb-threatening/critical ischaemia for a long time, and you will start to see loss of skin and underlying structures: Mainly in the form of arterial ulcers and gangrene in areas.

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10
Q

How do you explain to a patient what arterial ulcers are?

A

An open sore in the skin caused by lack of blood flow in the arteries

They occur because lack of oxygen to the arteries causes a break in the skin, then this can extend deeper into the leg until it reaches the bone

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11
Q

How would you explain to a patient how to recognise arterial ulcers, in 4 ways?

A

Location: They usually form in bony areas and pressure points, such as the outside heel, outer toes and ankle bones

Look: Very defined round shape as if the a hole has been ‘punched out’ in the skin, look deep, have red/yellow/black base colour

Feeling: Very painful, and the pain is better when dangling leg and is worse at night when elevated and rested

Other signs to look for: There can be hair loss around the ulcer area so the skin looks shiny and smooth, nails can also look different

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12
Q

How do you explain to a patient what gangrene is?

A

Gangrene is when the lack of blood supply has caused the skin and underlying structures to die. It usually starts in fingers and toes, then spreads up arms and legs

Dry gangrene: The part of the limb that is dead but not infected, so looks black/purple/blue and shrivelled/dry

Wet gangrene: The part of the limb that is dead has become infected, so looks wet, swollen and leaks a foul-smelling pus

Gas gangrene: The part of the limb that is dead has become infected with a type of bacteria that produces gas, so when you touch the gangrenous area it makes a cracking/popping sound due to trapped gas

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13
Q

How do you explain to a patient what acute limb ischaemia is?

A

Acute limb ischaemia is the most serious form of peripheral arterial disease, as it can be life-threatening so needs emergency treatment

ALI is caused by a sudden and large decrease in blood flow to a limb, which can lead to damage in the structures and limb loss (need for amputation)

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14
Q

How do you explain to a patient what the main causes of acute limb ischaemia are?

A

Usually the sudden decrease in blood flow occurs due to a blood clot that forms in the artery, or a mass eg. Fatty deposit that breaks loose and travels through the blood stream until it gets lodged in the artery

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15
Q

Give 6 examples of cardiac embolic risk factors for acute limb ischaemia?

A

There are several heart conditions that can cause blood clots or masses to form in the heart, then these can travel to peripheral arteries and cause ALI.

Atrial fibrillation

Heart attack

Infective endocarditis

Valve diseases

Prosthetic heart valves

Atrial myxoma

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16
Q

Give 2 examples of arterial embolic risk factors for acute limb ischaemia?

A

Atherosclerosis

Aneurysm: Emboli can lodge within peripheral aneurysms and block off blood flow

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17
Q

Give 3 examples of thrombotic risk factors for acute limb ischaemia?

A

Previous arterial surgeries eg. Bypass grafts, angioplasty, stents can form blood clots

Hyper coagulable state

Entrapment syndrome

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18
Q

How do you explain to a patient the main symptoms of acute limb ischaemia?

A

Pain: Sudden onset, severe ‘thunder-stroke’, burning/cramping pain that is constant, can be worse at night when lying down

Pallor: Limb looks white pale, cyanotic or mottled

Pulselessness: Ankle pulses are always absent

Poikilothermia: Inability to regulate body temperature so limb is always cold

Paraesthesia: Reduced sensation or numbness in limb

Paralysis or motor loss

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19
Q

How do you explain to a patient how peripheral arterial disease is diagnosed?

A

Initially they will have physical examinations and the blood pressure measured in their ankles and arms using a type of ultrasound scan, and an ECG to monitor heart activity

They will also have blood tests to find risk factors like high cholesterol, diabetes and to check the health of the structures in the limbs, as these can release certain substances if damaged

They can also have specialist imaging of their heart and arteries, to identify any emboli or thrombi

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20
Q

How do you explain to a patient how vascular conditions are treated?

A

There are 2 mainstays of treatment:

  1. Lifestyle changes
  2. Management of risk factors by medications: Aspirin, statin/ezetimibe, metformin/SSGLT2I, blood pressure medications
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21
Q

How do you explain to a patient what lifestyle changes are recommended to treat vascular conditions?

A

Stop smoking

Changing diet: Eat more fruit and vegetables, whole grain foods, protein with less fat like skinless chicken breast, healthy fats like olive oil and eat less salty foods

Exercise: Use ‘stop-start’ method, where you walk until pain becomes intolerable, then rest and repeat until you have done 30 min walking in total. Can also join supervised vascular exercise classes

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22
Q

Which medications are used to treat high cholesterol, in vascular conditions?

A

Statin

Ezetimibe

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23
Q

How do you explain to a patient what a statin is, and how it can treat vascular conditions?

A

A statin is a drug that lowers the level of a type of cholesterol in your bloodstream, called low-density lipoprotein.

Low density lipoprotein is classed as ‘bad cholesterol’ as it can build up in blood vessels and form plaques, which can break off and cause blood flow restrictions in other arteries. A statin reduces LDL levels, so it is less likely that plaques will form.

Atorvastatin, simvastatin

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24
Q

What are the main side effects of statins?

A

Muscle pain, weakness or cramping

Constipation or diarrhoea

Headaches

Sleep problems and fatigue

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25
How do you explain to a patient when to take statins?
Take once a day, can be at anytime as long as you stick to the same time every day Can take with or without food, but take with food if it makes you nauseous Swallow tablets whole with a drink of water, if its a chewable tablet then you can chew it
26
What medication is used to treat atherosclerosis and thrombosis, in vascular conditions?
Antiplatelet Usually aspirin
27
What are the main side effects of aspirin?
Easier bleeding eg. Nosebleeds, gum bleeding, heavier periods, bruising more Indigestion and diarrhoea Shortness of breath
28
How do you explain to a patient when to take aspirin?
Take aspirin once a day, if you miss a dose take it as soon as you remember but if you only remember on the next day then skip this dose and just take next dose at the usual time (never take 2 doses at once) Take it with or just after food Can be swallowed whole with water, dissolved in water
29
How do you explain to a patient what aspirin is and how it treats vascular conditions?
Aspirin is an antiplatelet drug Blood contains molecules that are called platelets. These help blood cells clump together to form blood clots, and also help to form fatty plaques in blood vessels. Aspirin prevents platelets from working, so less blood clots and plaques will form
30
Which medications are used to treat diabetes, in vascular condition management?
Metformin SGLT2 inhibitors
31
How do you explain to a patient what an aneurysm is?
A bulge in a blood vessel caused by a weakness in the blood vessel wall
32
How do you explain to a patient what an abdominal aortic aneurysm is?
The aorta is the biggest blood vessel in the body, and it comes directly from the heart and passes through the chest and abdomen. AAA occurs when the part of the aorta located in the abdomen becomes weakened and forms a bulge
33
How do you explain to a patient where else they can get aneurysms?
Brain aneurysm: A bulge in one of the blood vessels supplying the brain, which can cause a stroke Thoracic abdominal aneurysm: part of the aorta located in the chest becomes weakened and forms a bulge Popliteal aneurysms: A bulge in the blood vessel that runs behind the knee Mesenteric aneurysms: A bulge in the blood vessels that supply intestines
34
How do you explain to a patient what causes an aneurysm to form?
The artery inner lining becomes damaged and this triggers a cascade that causes the lining to break down The blood flowing through the artery puts pressure on the weakened lining, which causes it to swell and bulge outwards: This is the aneurysm
35
What are the different pathological origins of aneurysms? MAD SCAB?
Mycotic: Haematogenous spread of bacterial infection to arterial wall Atherosclerotic: Atherosclerotic process damages wall and causes it to become thinner Dissecting: Tear in the inner lining of artery allows blood to flow between the layers of the wall, creating a false channel that blood fills Syphilitic: Aneurysm caused by tertiary stage of syphilitic infection Capillary microaneurysm: Bulging of capillary wall Arteriovenous fistula: Artery and vein connect directly, allowing blood to flow incorrectly Berry/saccular aneurysm: Aneurysm that looks like a round outpouching (berry on a vine)
36
What are the 3 types of AAA, and which is the most common?
Infrarenal AAA: Located below renal arteries (most common) Pararenal AAAs: Aneurysm extends up to renal arteries but doesn’t necessarily involve them Juxtarenal AAA: Bulge extends up to, but not including, the renal arteries Suprarenal AAA: Bulge involves at least one renal artery origin
37
What are the 3 types of thoracic aortic aneurysms?
Ascending aortic aneurysm: In part of aorta that rises from heart Descending aortic aneurysm: In part of aorta that runs down through chest and into abdomen Aortic arch aneurysm: In upper curved area of aorta that gives off vessels to head and neck
38
How do you explain to the patient the risk factors for aneurysms?
Being male Over 65 yrs old If you have a first-degree relative with previous aneurysms or if you have had aneurysms before Genetic conditions: Marfans, Ehlers-Danlos, CTDs Smoking Metabolic conditions: High blood pressure, high cholesterol, PAD (diabetes is protective against aneurysms) High alcohol intake
39
How do you explain to a patient the symptoms of an unruptured AAA?
Usually you will not have any noticeable symptoms, or they will come on gradually AAA can also cause constant abdominal pain that radiates to back, pulsating feeling in abdomen that usually occur when abdomen or back are touched
40
How do you explain to a patient the symptoms of a ruptured AAA?
Thunderclap pain in abdomen or lower back Pulsating mass in abdomen Sweating and clammy skin Pallor/grey skin SOB Hypotension signs: Dizziness, Syncope
41
How do you explain to a patient the symptoms of a ruptured thoracic aortic aneurysm?
Thunderclap pain in chest arms neck jaw or upper back Difficulty breathing or swallowing Hoarse voice Persistent cough
42
How do you explain to a patient the symptoms of a ruptured brain aneurysm?
Thunderclap headache Blurred/double vision Pain above and behind eye Stiff neck Light sensitivity Confusion/difficulty thinking clearly Loss of balance Numbness weakness or paralysis on one side of face (aneurysm pressing on facial nerve)
43
If a patient has a unruptured aneurysm somewhere, what kind of symptoms can they have?
Asymptomatic or gradual onset of symptoms Pulsing sensation or pulsatile mass
44
How do you explain to a patient how an AAA is diagnosed?
Abdominal ultrasound: A quick and non-invasive test that can be done at the bedside Specialist tests like CT angiogram and digital subtraction angiography to see where exactly aneurysm is
45
How do you explain to a patient what AAA screening program is?
Ultrasound scan that is offered to all men aged 65 and over Checks for any bulging of the abdominal aorta and measures the current size This is for early detection of AAAs and to prevent complications if it is at risk of rupture
46
How do you explain to a patient what the management is if their abdominal aorta is less than 2.5 cm?
No management as this is a normal size
47
How do you explain to a patient what the management is if their abdominal aorta is 3-4.4 cm?
This is a small AAA Patient will have repeat ultrasound scans every year (every 12 months) Is managed with lifestyle changes and medications to reduce risk factors
48
How do you explain to a patient what the management is if their abdominal aorta is 4.5-5.4 cm?
This is a medium-sized AAA Patient will have repeat ultrasounds every 6 months if towards lower limit, and repeat ultrasounds every 3 months if towards upper limit
49
How do you explain to a patient what the management is if their abdominal aorta is 5.5 cm or more?
This is a large AAA Patient should have operation to reduce the size of the AAA even if they are having no symptoms, as there is a high risk of rupture
50
How do you explain to a car driver what they must do about driving if they have an AAA?
You must inform the DVLA if your aneurysm grows to 6cm. Your license will be suspended if your aneurysm grows to 6.5cm Your license will be reinstated after your aneurysm has been successfully treated.
51
How do you explain to a bus/coach/lorry driver what they must do about driving if they have an AAA?
You must inform the DVLA that you have an aneurysm. Your license will be suspended. Your license will be reinstated after your aneurysm has been successfully treated
52
What are the 3 indications for surgical repair of AAAs?
Large AAA even if it is asymptomatic (5.5 cm or more) AAA expanding at >1cm per year Symptomatic AAA in a patient who is otherwise fit
53
How do you explain to a patient the 2 types of AAA repairs?
Endovascular repair: minimally invasive procedure where a graft is inserted through small incisions in the groin and guided to the aneurysm site Open surgical repair: Involves a large incision in the abdomen or chest, and the damaged portion of the aorta is replaced with a graft
54
In peripheral arterial disease, which 4 groups of secondary prevention drugs are prescribed?
To treat atherosclerosis: Antiplatelet (aspirin) To treat cholesterol: Statin or ezetimibe To treat hypertension: ARB/ACE/CCB/thiazide-like diuretic/spironolactone/beta-blocker/alpha-blocker To treat diabetes: Metformin, SGLT2 inhibitors
55
In aneurysms, which 4 groups of secondary prevention drugs are prescribed?
To treat atherosclerosis: Antiplatelet (aspirin) To treat cholesterol: Statin or ezetimibe To treat hypertension: ARB/ACE/CCB/thiazide-like diuretic/spironolactone/beta-blocker/alpha-blocker To treat diabetes: Metformin, SGLT2 inhibitors
56
How do you explain to a patient the benefits and disadvantages of EVAR?
Benefits: Minimally invasive due to small cuts only, shorter hospital stay, quicker recovery Disadvantages: Higher chance of aneurysm reoccurrence, lifelong regular monitoring for endoleaks, only suitable for selective anatomy
57
How do you explain to a patient what endoleaks are?
After a stent is placed inside the aneurysm sac, blood still can leak outside a stent graft and within an aneurysm sac: This is called an endoleak They are common complications of EVAR, so you need lifelong regular monitoring to make sure that endoleaks don't form
58
What are the 5 types of endoleaks?
Type 1: Blood leaks from the ends of the stent graft due to poor seal Type 2: Retrograde flow into the aneurysm sac from branch vessels (most common) Type 3: Leak through graft fabric defect Type 4: Leak through graft due to high porosity Type 5/endotension: Leak through graft into aneurysmal sac without any visible endoleaks
59
How do you explain to a patient the benefits and disadvantages of open surgical repair for aneurysms?
Benefits: Less chance of reoccurrence, minimal monitoring needed afterwards, can be used for different types of aneurysms Disadvantages: Higher risk of complications during operation, longer hospital stay, longer recovery
60
How do you explain to a patient what a DVT is?
A blood clot that develops in a deep vein, usually in the pelvis or legs Deep veins are the blood vessels that carry blood back to the heart, and they are found closer to your bone and far below the skin
61
How do you explain to a patient the risk factors for developing a DVT? THROMBOSIS
T: Travel (long hours), trauma, thrombophilia (haemophilia A,B,C) H: Hypercoagulable state, HRT R: Recreational drugs, IV drug user O: Old age M: Malignancy eg. polycythemia, thrombocythemia, prostate, liver, GI, kidney, breast B: Birth control pills O: Obesity, obstetric (pregnancy) S: Surgery I: Immobilisation or iatrogenic eg. infected indwelling catheters or pacemaker wires S: Serious illness
62
How do you explain to a patient why it is important to diagnose and treat DVTs urgently?
Because the blood clot can travel to the lungs and cause a potentially fatal pulmonary embolism
63
How do you explain to a patient what a PE is?
Blood clot in a blood vessel supplying the lungs, which causes lungs to be deprived of blood This can be life-threatening
64
How do you explain to a patient why a PE can be life-threatening?
Less blood reaches the lungs, so they will be damaged and will not be able to transport as much oxygen into the blood that supplies the rest of your organs Blockage in lung arteries also puts pressure on right-side of heart as it needs to work harder to pump blood past the blood clot: Leads to right-sided heart failure
65
How do you explain to a patient the 4 symptoms of a DVT?
Throbbing/cramping pain that is worse when walking or standing, and feels better when leg is elevated (Pain is located in calf or thigh) Skin looks red or darker Skin feels warmer than non-affected areas Veins along the leg look swollen and are tender when touched
66
How do you explain to a patient the symptoms of a PE?
Sudden SOB Haemoptysis: Coughing up blood Palpitations (heart racing) Sharp chest pain, worse when breathing in Sweating Dizziness, fainting Anxiety
67
How do you explain to a patient the initial investigation for suspected DVT?
Calculate DVT Well's score: Estimates likeliness of DVT, which is used to determine if further testing is needed to confirm diagnosis
68
How do you explain to a patient the initial investigation for suspected PE?
Calculate PE Well's score: Estimates likeliness of PE, which is used to determine if further testing is needed to confirm diagnosis
69
If a patient with suspected DVT has a Well's score 2 or more, what is the next step in treatment?
DVT WELL'S SCORE 2 OR MORE: DVT LIKELY 1. Proximal leg vein ultrasound with the result available within 4 hours 2. If scan isn't available: Offer a D-dimer test, then interim therapeutic anticoagulation and a proximal leg vein ultrasound scan with the result available within 24 hours
70
If a patient with suspected DVT has a Well's score 0/1, what is the next step in treatment?
Offer a D-dimer test with the result available within 4 hours if possible. If the D-dimer result cannot be obtained within 4 hours, offer interim therapeutic anticoagulation while awaiting the result
71
If a patient with DVT Well's score 2 or more has a positive leg vein ultrasound, what is the next step in treatment?
Can now diagnose DVT Stop any interim anticoagulation and start official treatment
72
If a patient with DVT Well's score 0/1 has a positive D-dimer, what is the next step in treatment?
Proximal leg vein ultrasound scan with the result available within 4 hours If the result cannot be obtained within 4 hours, offer interim therapeutic anticoagulation and a proximal leg vein ultrasound scan with the result available within 24 hours
73
If a patient with DVT Well's score 0/1 has a negative D-dimer, what is the next 3 steps in treatment?
Stop interim therapeutic anticoagulation. Consider an alternative diagnosis. Advise the person that it is unlikely they have DVT, but they should be aware of the signs and symptoms of DVT and seek medical help if symptoms worsen or they experience chest pain or breathing difficulties
74
If a patient with DVT Well's score 0/1 has a positive D-dimer, then a negative leg ultrasound, what is the next step in treatment?
Stop interim therapeutic anticoagulation. Consider an alternative diagnosis. Advise the person that it is unlikely they have DVT, but they should be aware of the signs and symptoms of DVT and seek medical help if symptoms worsen or they experience chest pain or breathing difficulties
75
If a patient with DVT Well's score 0/1 has a positive D-dimer, then a positive leg ultrasound, what is the next step in treatment?
Can now diagnose DVT Stop any interim anticoagulation and start official treatment
76
If a patient with DVT Well's score 2 or more has a negative leg vein ultrasound, what is the next step in treatment?
Offer a D-dimer test with the result available within 4 hours if possible. If the D-dimer result cannot be obtained within 4 hours, offer interim therapeutic anticoagulation while awaiting the result
77
If a patient with DVT Well's score 2 or more has a negative leg vein ultrasound, then a positive D-dimer, what is the next step in treatment?
Stop interim therapeutic anticoagulation Repeat proximal leg vein ultrasound 6 to 8 days later: If positive then diagnose DVT and start official treatment
78
If a patient with DVT Well's score 2 or more has a negative leg vein ultrasound, then a negative D-dimer, what is the next step in treatment?
Stop interim therapeutic anticoagulation. Consider an alternative diagnosis. Advise the person that it is unlikely they have DVT, but they should be aware of the signs and symptoms of DVT and seek medical help if symptoms worsen or they experience chest pain or breathing difficulties
79
How do you explain to a patient the alternative diagnoses for DVT?
Cellulitis Superficial thrombophlebitis Chronic venous insufficiency Baker's cyst Allergic reaction eg. insect bite
80
If a patient with suspected PE has a Well's score 4 or more, what is the next step in treatment?
Admit patient to hospital for immediate CTPA Offer interim therapeutic anticoagulation (if possible, choose an anticoagulant that can be continued if PE is confirmed), and arrange hospital admission
81
If a patient with suspected PE has a Well's score 0-3, what is the next step in treatment?
Offer a D-dimer test with the result available within 4 hours: If the test result cannot be obtained within 4 hours, offer interim therapeutic anticoagulation while awaiting the result (if possible, choose an anticoagulant that can be continued if PE is confirmed)
82
If a patient with PE Well's score 4 or more has a positive CTPA, what is the next step in treatment?
Diagnose PE Start official treatment
83
If a patient with PE Well's score 0-3 has a positive D-dimer, what is the next step in treatment?
Admit patient to hospital for immediate CTPA Offer interim therapeutic anticoagulation (if possible, choose an anticoagulant that can be continued if PE is confirmed), and arrange hospital admission
84
If a patient with PE Well's score 0-3 has a negative D-dimer, what is the next step in treatment?
Stop interim coagulation Consider alternative diagnoses If DVT is suspected, then use DVT investigation pathway
85
If a patient with PE Well's score 4 or more has a negative CTPA, what is the next step in treatment?
Stop interim coagulation Consider alternative diagnoses If DVT is suspected, then use DVT investigation pathway
86
How do you explain to a patient the alternative diagnoses for PE?
COPD exacerbation Pneumonia Pericarditis Heart attack
87
What interim anticoagulation is given for DVT or PE?
Apixaban or rivaroxaban first-line If apixaban or rivaroxaban are unsuitable, consider: Low molecular weight heparin (LMWH) for at least 5 days, followed by dabigatran or edoxaban OR LMWH alongside a vitamin K antagonist (warfarin) for at least 5 days
88
Whilst the patient is taking interim anticoagulation, which blood tests do you do to prepare for long-term anticoagulation?
FBC, U&Es, LFTs, clotting tests
89
How long does a patient take long-term anticoagulation for if they had a provoked DVT/PE?
3 months
90
How long does a patient take long-term anticoagulation for if they had an unprovoked DVT/PE?
3 months, then reassess for any causes and if they need longer-term
91
How long does a patient take long-term anticoagulation for if they have recurrent DVT/PE?
Lifelong if the bleeding risk is suitable
92
How long does a patient take long-term anticoagulation for if they have DVT/PE due to thrombophilia eg. antiphospholipid syndrome?
Lifelong
93
How long does a patient take long-term anticoagulation for if they have DVT/PE due to active cancer?
Throughout active cancer and cancer treatment
94
How do you explain to a patient what apixaban or rivaroxaban are, and how do they treat DVT/PE?
Apixaban and rivaroxaban are both a type of DOAC. DOAC means direct oral anticoagulant. In the body, there are different pieces in your blood called clotting factors. The clotting factors join together in a pattern until they have formed a blood clot. A DOAC like apixaban or rivaroxaban prevents factor 10a from joining the pattern, which means that the blood clot can't be completed.
95
How do you explain to a patient what dabigatran is, and how does is treat DVT/PE?
Dabigatran is a type of DOAC. In the body, there are different pieces in your blood called clotting factors. The clotting factors join together in a pattern until they have formed a blood clot. Dabigatran prevents factor thrombin from joining the pattern, which means that the blood clot can't be completed.
96
How do you explain to a patient what warfarin is, and how does it treat DVT/PE?
Warfarin is an anticoagulant, meaning it prevent blood from clotting In the body, there are different pieces in your blood called clotting factors. The clotting factors join together in a pattern until they have formed a blood clot. Vitamin K is needed to activate these clotting factors. Warfarin blocks vitamin K, so that the clotting factors can't be activate and a blood clot can't be completed.
97
How do you explain to a patient how to take a DOAC?
Take DOAC once a day, if you miss a dose take it as soon as you remember but if you only remember on the next day then skip this dose and just take next dose at the usual time (never take 2 doses at once) Take it with or without food, if its rivaroxaban its better to take with food (better absorption) Can be swallowed whole with water
98
How do you explain to a patient how to take warfarin?
Take warfarin once a day in the evening, if you miss a dose take it as soon as you remember but if you only remember on the next day then skip this dose and just take next dose at the usual time (never take 2 doses at once) Take with or without food
99
How do you explain to a patient the side effects of anticoagulants?
More bleeding: Nosebleeds, gum bleeds, heavier periods, black stool, easier bruising, blood in urine (Recurrent/severe bleeding: Call 111 or A&E) Diarrhoea, indigestion Dizziness headaches
100
How do you explain to a patient how DOACs are monitored?
No regular monitoring is needed for DOACs as they are quite safe, but you will still have general check ups and blood tests You will be given a yellow card: This is your anticoagulant alert card that lets healthcare providers know that you are taking anticoagulants Yellow card scheme: You can report any side effects here
101
How do you explain to a patient how warfarin dose is monitored?
You will have a regular blood test called the international normalised ratio (INR). It measures how long it takes your blood to clot. The longer your blood takes to clot, the higher the INR. Most people taking anticoagulants have a ratio of between 2 and 3.5. This means their blood takes 2 to 3.5 times longer to clot than usual. The dose of warfarin you need depends on your blood test result. If the blood test result has gone up or down, your warfarin dose will be increased or decreased. You'll have a test every 1 or 2 days when you first start taking warfarin, then once or twice a week, until your ratio is stable at the target level. Once your blood test results are stable, you might only need a blood test up to once every 12 weeks Anticoagulant alert card and yellow book (record your doses in here when you take them, bring to appointments)
102
How do you explain to a patient 5 lifestyle changes to prevent DVT/PE?
Lose weight, as obesity is a risk factor Regular exercise, as prolonged inactivity is a risk factor Smoking cessation Staying hydrated, as this improves blood circulation Healthy diet