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Flashcards in Day 1 (BB & UA) Deck (98)
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1

Antigens

- Gene products expressed on membrane
- Protein, glycoprotein or carbohydrate

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- Gene products expressed on membrane
- Protein, glycoprotein or carbohydrate

Antigens

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Differences between blood groups

- Antigen's structure and location on RBC
- Antibodies they elicit

4

Genes

- Basic units of inheritance that encode for traits/characteristics
- Found at specific locations (loci) on chromosomes

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- Basic units of inheritance that encode for traits/characteristics
- Found at specific locations (loci) on chromosomes

Genes

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Alleles

Different forms of the same gene

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Different forms of the same gene

Alleles

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Chromosomes

- Double strands of DNA that carry genetic information
- 23 pairs in humans

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- Double strands of DNA that carry genetic information
- 23 pairs in humans

Chromosomes

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Gene Transmission

Transmitted via mitosis and meiosis

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Gene inheritance

Inherited in a Mendelian fashion (one from each parent)

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Law of Independent Assortment

- Antigens on different chromosomes are inherited and expressed independently
- Genes far apart on a chromosome are inherited independently due to crossing over during mitosis
- Genes close together are inherited together

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Haplotype

Genes close together on the same chromosome that are inherited together (linkage disequilibrium)

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Cis genes

Genes inherited on the same chromosome

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Trans genes

Genes inherited on the opposite chromosomes

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Polymorphic genes

Genes that express two or more phenotypes

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Genes close together on the same chromosome that are inherited together (linkage disequilibrium)

Haplotype

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Genes inherited on the same chromosome

Cis genes

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Genes inherited on the opposite chromosomes

Trans genes

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Genes that express two or more phenotypes

Polymorphic genes

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Antithetical genes

- Genes that are 'opposite'
- Can only express one antigen or the other

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- Genes that are 'opposite'
- Can only express one antigen or the other

Antithetical genes

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Null phenotype

Occurs when a gene is not expressed

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Occurs when a gene is not expressed

Null phenotype

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Amorphs

- silent genes
- can cause null phenotypes

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Suppressor genes

- inhibit expression of another gene
- can cause null phenotypes

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Homozygous inheritance

Both inherited alleles are identical

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Heterozygous inheritance

Inherited genes are different

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Trait

Detectable or observable gene product

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Direct exclusion

Child has traits that neither parent has