Day 8 Obstetrics Flashcards
A pregnant woman has serum alpha feto-protein levels measured.
- *Which one of the following is associated with a low alpha-feto protein level?
(2) **
AFP
- raised in neural tubes defects
- decreased in Down’s syndrome
A 46-year-old woman has come into her GP.
She is planning on becoming pregnant, and would like advice about simple lifestyle changes and medications she should be taking, and the GP mentions that the woman should be taking the high dose (5 mg) folic acid.
What are the reasons for taking high dose folic acid?
Women are considered higher risk if any of the following apply:
- either partner has a NTD, they have had a previous pregnancy affected by a NTD, or they have a family history of a NTD
- the woman is taking antiepileptic drugs or has coeliac disease, diabetes, or thalassaemia trait.
- the woman is obese (defined as a body mass index [BMI] of 30 kg/m2 or more).
Which changes would you expect to see in a healthy pregnant patient as compared to before pregnancy?
Normal laboratory findings in pregnancy:
- reduced urea
- reduced creatinine
- increased urinary protein loss
A 32-year-old gravid 3, para 2 at 24 weeks gestation attends an antenatal clinic and wishes to discuss delivery options for her pregnancy.
On history, you find that her previous pregnancies were delivered by vaginal and elective caesarean section respectively.
What is an absolute contraindication for vaginal delivery following a previous cesarean section?
(2)
Vertical (classic) caesarean scar
previous episodes of uterine rupture
A 23-year-old woman has come to the emergency department.
She is 37 weeks pregnant, and is complaining of a temperature and feeling generally unwell.
She is seen by the emergency department doctors and sent to the obstetric unit.
There, she is found to have a fever of 38ºC and to be tachycardic at 110 bpm.
The fetus is found to be tachycardic as well.
She says she has had no other symptoms, except having an episode of what she said describes as urinary incontinence 3 weeks ago, and some discharge afterwards.
What is the most likely cause of her presenting complaint?
Chorioamnionitis
You should think chorioamnionitis in women with preterm-PROM with a triad of maternal pyrexia, maternal tachycardia, and fetal tachycardia
A 19-year-old woman who is 9 weeks into her first pregnancy is seen in the early pregnancy assessment unit with vaginal bleeding.
Her ultrasound scan confirms a viable intrauterine pregnancy.
However, the high vaginal swab has isolated group B streptococcus (GBS).
How should she be managed?
Intrapartum intravenous benzylpenicillin only.
GBS is a vaginal commensal isolated in many women. It is known to be the most frequent cause of severe early-onset infection in the newborn and can cause significant morbidity and mortality.
A 28-year-old woman self-presents to the Emergency Department, extremely concerned regarding her pregnancy.
She is 33 weeks pregnant and thus far, the pregnancy has been uncomplicated.
However, several hours ago whilst out shopping, she felt a sudden gush of fluid from her vagina and a subsequent wetness of her underwear.
Her observations have already been taken by one of the triage nurses and are stable, within normal ranges.
Given the likely diagnosis, what is the first-line investigation?
(2)
Speculum examination is first line
Careful speculum examination to look for pooling of amniotic fluid in the posterior vaginal vault is the first-line investigation for preterm prelabour rupture of the membranes
Ultrasound may also be useful to show oligohydramnios.
Preterm prelabour rupture of the membranes management
(5)
Management
- admission
- regular observations to ensure chorioamnionitis is not developing
- oral erythromycin should be given for 10 days
- antenatal corticosteroids should be administered to reduce the risk of respiratory distress syndrome
- delivery should be considered at 34 weeks of gestation - there is a trade-off between increased risk of maternal chorioamnionitis with a decreased risk of respiratory distress syndrome as the pregnancy progresses
A mother brings her 6 year-old son to clinic with a widespread rash.
You diagnose chickenpox.
You know his mother, who is also a patient at the practice, is currently 20 weeks pregnant with her second child.
What action should you take, if any, regarding her exposure to chickenpox?
You should ask pregnant women exposed to chickenpox if they have had the infection before. If they say no or are unsure, varicella antibodies should be checked.
If it is confirmed they are not immune, varicella immunoglobulin should be considered. It can be given at any point in pregnancy and is effective up to 10 days after exposure.
A 27 year old woman attends her GP with breast pain.
She is 2 weeks postpartum and is exclusively breastfeeding.
She complains of a 3 day history of worsening right sided breast pain, which has not improved with continued feeding and expressing.
On examination, she appears well, her temperature is 38ºC.
There is a small area of erythema superior to the right nipple, which is tender to touch. She has no known allergies.
What would be the most appropriate management?
(2)
The first-line antibiotic is oral flucloxacillin for 10-14 days.
Breastfeeding or expressing should continue during treatment.
A woman has a vaginal delivery of her first child.
Although the birth was uncomplicated, she suffers a tear which extends from the vaginal mucosa into the submucosal tissue, but not into the external anal sphincter.
Which degree tear is this classed as?
- 1st degree = tear within vaginal mucosa only
- *- 2nd degree = tear into subcutaneous tissue**
- 3rd degree = laceration extends into external anal sphincter
- 4th degree = laceration extends through external anal sphincter into rectal mucosa
Sarah is a 29-year-old woman who comes to see you for a follow-up visit. You initially saw her 1 month ago for low mood and referred her for counselling. She states she is still feeling low and her feelings of anxiety are worsening. She is keen to try medication to help.
Sarah has a 4-month-old baby and is breastfeeding.
Which are the most appropriate medications for Sarah to commence?
(2)
Sertraline or paroxetine are the SSRIs of choice in breastfeeding women
Sertraline or paroxetine are the SSRIs of choice in breastfeeding women as whilst they are secreted in low levels in the breast milk it is not thought to be harmful to the infant.
A 28-year-old woman is admitted to the labour ward at 38+4 weeks gestation.
This is her first pregnancy and she tells you that contractions started around 10 hours ago.
On examination, her cervix is positioned anteriorly, is soft, and is effaced at around 60-70%.
Cervical dilatation is estimated at around 3-4cm and the fetal head is located at the level of the ischial spines.
She has had no interventions performed as of yet.
What intervention should be performed?
She has a bishop score of 10
No interventions required
A Bishop’s score of ≥ 8 indicates that the cervix is ripe, or ‘favourable’ - there is a high chance of spontaneous labour, or response to interventions made to induce labour

What is a bishop score?
Interpretation
a score of < 5 indicates that labour is unlikely to start without induction
a score of ≥ 8 indicates that the cervix is ripe, or ‘favourable’ - there is a high chance of spontaneous labour, or response to interventions made to induce labour
When is Vaginal prostaglandin E2 used?
(2)
- Vaginal prostaglandin E2 is the preferred method of induction of labour but as this patient is only 10 hours into the first stage of labour
and
- she has a bishop score of 10
When is Maternal oxytocin infusion used?
(2)
Maternal oxytocin infusion can be used if labour is not progressing and other methods of induction have been tried but wouldn’t be appropriate in this scenario at this stage.
Oxytocin infusion carries the risk of uterine hyperstimulation.
When is an amniotomy performed?
(2)
Amniotomy is the artificial rupturing of membranes and can be performed if other methods have failed to induce labour or if vaginal prostaglandin E2 is contra-indicated.
Amniotomy carries the risk of infection, umbilical cord prolapse and baby moving into breech position if the fetal head is not engaged.
A woman who is at 12 weeks gestation presents to her antenatal appointment for her combined screening test.
She consents to, and undergoes, the standard screening test involving blood tests being taken and an ultrasound scan.
She is subsequently informed that her results may indicate Down’s syndrome, and is invited to discuss this further.
What results would be expected in this instance?
(3)
Down’s syndrome is suggested by
raised HCG
low PAPP-A
thickened nuchal translucency
A 29-year-old woman with her first pregnancy presents to you at 30-weeks gestation with itchiness.
There is no rash on examination and after referral to an obstetrician, she is confirmed to be suffering from intrahepatic cholestasis of pregnancy.
What should she be treated with?
The patient mentions her obstetrician said something about her labour but she was not sure.
What needs to be planned regarding this patient’s labour?
She should initially be treated with ursodeoxycholic acid.
Induction of labour at 37-38 weeks gestation
A 36-year-old woman who is currently 32 weeks pregnant has been monitoring her capillary blood glucose (CBG) at home following a diagnosis of gestational diabetes mellitus (GDM) 4 weeks ago.
She has been given appropriate dietary and exercise advice, as well as review by a dietitian.
She has also been taking metformin and has been on the maximum dose for the past 2 weeks.
Fetal growth scans have been normal with no signs of macrosomia or polyhydramnios.
She has brought her CBG diary today, which shows that her mean pre-meal CBG is 5.9 mmol/L and mean 1-hour postprandial CBG is 8.3 mmol/L.
What is the most appropriate management?
In gestational diabetes, if blood glucose targets are not met with diet/metformin then insulin should be added
You are a male FY1 working in obstetrics. A 33-year-old female is on the ward in labour, 10 minutes ago she suffered a placental abruption and is in need of emergency care.
Her midwife comes to see you, informing you that she is requesting to only be seen and cared for by females.
What do you say?
Ask the midwife to immediately summon senior medical support, regardless of gender
While patients do have a right to choose their own doctor, this doesn’t apply in emergency situations where treatment is needed to save the life of the patient.
Hepatitis B and pregnancy
(4)
Basics
all pregnant women are offered screening for hepatitis B
babies born to mothers who are chronically infected with hepatitis B or to mothers who’ve had acute hepatitis B during pregnancy should receive a complete course of vaccination + hepatitis B immunoglobulin
there is little evidence to suggest caesarean section reduces vertical transmission rates
hepatitis B cannot be transmitted via breastfeeding (in contrast to HIV)
A 36-year-old nulliparous woman is admitted in labour at 37 weeks gestation.
On examination, the cervix is 7 cm dilated, the head is direct Occipito-Anterior, the foetal station is at -1 and the head is 2/5ths palpable per abdomen.
The cardiotocogram shows late decelerations and a foetal heart rate of 100 beats/min which continue for 15 minutes.
How should this situation be managed?
(4)
The cardiotocogram is very concerning (the late decelerations which are a worrying sign especially in the context of foetal bradycardia) and indicates that the baby needs to be delivered immediately.
Instrumental delivery is not possible because the cervix is not fully dilated and the head of the baby is high.
Oxytocin and vaginal prostaglandin are contraindicated due to foetal distress.
Therefore the safest approach in this case is an emergency caesarian section.
A 28-year-old woman rings up the surgery for the results of her oral glucose tolerance test. She is 25 weeks pregnant and had a glucose tolerance test as she has a body mass index of 34kg/m².
Her results are as below:
Fasting glucose = 5.4 mmol/L
2-hour glucose = 7.8 mmol/L
What is the single best description of these results?
Gestational diabetes due to a raised 2-hour glucose
Gestational diabetes can be diagnosed by either a:
- fasting glucose is >= 5.6 mmol/L, or
- 2-hour glucose level of >= 7.8 mmol/L
- ‘5678’















