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Flashcards in DD Bugs Brainscape Deck (52)
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1

Staphylococcus aureus- Gram Stain and Characteristics

Gram + cocci, B-hemolytic, and mannitol fermenters

2

Staphylococcus aureus- Disease Association

cutaneous infections, TSS, food poisoning, pneumonia, foreign body infections, endocarditis

3

Staphylococcus aureus -Virulence Trait and Factors Eliciting an Immune Response

Coagulase (fibrin walls off abscess, no phagocytosis) and Protein A (B-barrel toxin that binds to Fc-IgG -> no complement or phagocytosis), superantigen toxin -> TSS and food poisoning.

4

Staphylococcus aureus -Common Antibiotic Resistance Mechanism

B-lactamase (MRSA) and change in PBP.

5

Staphlycoccus epidermis- Gram Stain and Characteristics

Gram + cocci, catalase and urease +

6

Staphlycoccus epidermis-Disease Association

Infection with foreign bodies, i.e. catheters, prothesis and heart valves

7

Staphlycoccus epidermis-Virulence Trait

Extracellular glycocalyx (slime) to help adhere

8

Streptococcus pyogenes (GAS)- Gram Stain and Characteristics

Gram + Cocci

9

Streptococcus pyogenes (GAS)- Disease Association

Pharyngitis, skin and wound infections, post-strep (glomerunephritis and rheumatic fever)

10

Streptococcus pyogenes (GAS)- Virulence Trait

M protein; resist phagocytosis and hydrolytic enzymes

11

Streptococcus pneumonia- Gram Stain and Characteristics

gram + diplococci, alpha hemolytic and bile soluble

12

Streptococcus pneumonia- Disease Association

BS MOPS- Bacteremia, Septicemia, Meningitis, Otitis media, Pneumonia!, Sinusitis

13

Streptococcus pneumonia- Virulence Trait

Antiphagocytic polysacchardie capsule (also elicits response), IgA catalase

14

Viridans streptococci- Gram Stain and Characteristics

Gram + cocci, alpha/non hemolytic, abundant in mouth

15

Viridans streptococci- Disease Association

Endocarditis (esp. after dental work)

16

Viridans streptococci- Virulence Trait

Dextran which allows for it to adhere to mouth and heart

17

Enterococcus faecalis and faecium- Gram Stain and Characteristics

Gram + cocci, normal flora of intestine (selected by therapy with cephalosporin)

18

Enterococcus faecalis and faecium- Disease Association

Do U <3 trees? UTI, endocarditis, biliary tree, and surgical wounds

19

Enterococcus faecalis and faecium- Common Antibiotic Resistance Mechanism

Vancyomycin resistant, nosocomial (pt to pt contact)

20

Clostridium difficile- Gram Stain and Characteristics

Gram + rods

21

Clostridium difficile- Disease Association

nosocomial diarrhea, pseudomembranous colitis (resist from superinfection)

22

Clostridium difficile- Virulence Trait

exotoxin A: brush border (traveler's diarrhea), exotoxin B: depolymerize actin (pseudo. colitis)

23

Clostridium difficile- Common Antibiotic Resistance Mechanism

Resistant to most antibiotics (except Vancomycin and Metronidazole)

24

Clostridium tetani- Gram Stain and Characteristics

gram + rod, soil, GI tract, and rusty nails

25

Clostridium tetani- Disease Association

tetanus (spastic paralysis, lock jaw, and arching back)

26

Clostridium tetani- Virulence Trait

Tetanus toxin; retrograde axonal transport of toxin to CNS, blocks inhibitory interneurons leading to spastic paralysis)

27

Clostridium botulinum- Gram Stain and Characteristics

gram + rods, spore forming

28

Clostridium botulinum- Disease Association

botulism (jaundice and flaccid paralysis)

29

Clostridium botulinum- Virulence Trait

botulinum toxin (blocks ACh transmission, resulting in flaccid paralysis)

30

Clostridium perfringens- Gram Stain and Characteristics

gram + rod