December 1

Question 1

what drug is used in pts with bilateral adrenal disease?

Answer 1

spironolactone

Question 2

blood results in myeloma?

Answer 2

ESR and CRP high
paraprotein and BJP
Increase in marrow plasma cells

Question 3

bone lesions in myeloma?

Answer 3

lytic

Question 4

lead poisoning?

Answer 4

GI upset
weakness
kidney injury

Question 5

TCA poisoning?

Answer 5

tachy
drowsy
dry mouth
hallucinations
SVT

Question 6

salicylate poisoning?

Answer 6

tinnitus
sweating
met acidosis
hypoghlycaemia

Question 7

iron poisoning?

Answer 7

GI bleed
met acidosis
hypovolaemia

Question 8

features of fragile X?

Answer 8

large testicles
MV prolapse

Question 9

features of edwards? what chromosome?

Answer 9

trisomy 18
young death (weeks)

Question 10

features of Pierre robin?

Answer 10

pushed back tongue
underdeveloped jaw

Question 11

do you give Abx for E coli diarrhoea?

Answer 11

NO
increase risk of HUS

Question 12

what tumours occur in MEN2a?

Answer 12

MTC
phaechromocytoma
hyperparathyroidism

Question 13

what tumours occur in MEN1?

Answer 13

Pituitary adenomas
pancreatic tumours
hyperparathyroidism

Question 14

where is the mutation in MEN?

Answer 14

RET gene

Question 15

antibody in PBC?

Answer 15

AMA

Question 16

what IBD is PSC more assoc with?

Answer 16

UC

Question 17

e.g of 1st and 2nd gen antipsychotic?

Answer 17

1st - haloperidol
2nd - olanzapine

Question 18

what is sore - epi of scleritis?

Answer 18

SCLERITIS

Question 19

what electrolyte abnormality do SSRis cause?

Answer 19

hyponatraemia

Question 20

how long should anti depressants be continued for?

Answer 20

6 months

Question 21

how long do symptoms need to last to be classified a depressive illness?

Answer 21

2 weeks

Question 22

atypical antipsychotics increase risk of what in elderly?

Answer 22

VTE
stroke

Question 23

when should clozapine be used?

Answer 23

if two previous antipsychotics have been tried and not worked

Question 24

what is raised in anorexia?

Answer 24

GH
glucose
cortisol
cholesterol
caritonaemia

Question 25

what antidepressant should be given post MI?

Answer 25

sertraline

Question 26

what arrythmia can citalopram cause?

Answer 26

torsades

Question 27

what antidepressant should be avoided on warfarin?

Answer 27

citalopram

Question 28

what is the difference between conversion and somatisation disorder?

Answer 28

conversion - FND somatisation - symptoms but not accepting of neg tests, >years

Question 29

what is the Tx for PTSD?

Answer 29

venlaflaxine SSRIs

Question 30

what cancer does COCP protect against?

Answer 30

ovarian

Question 31

how long after LMP can the menopause be classified as?

Answer 31

12 months if >50 24 if <50

Question 32

Tx for urge incontinence?

Answer 32

oxybutynin

Question 33

Tx for stress incontinence?

Answer 33

duloxetine

Question 34

what antibody indicates drug induced lupus?

Answer 34

anti histone

Question 35

cause of groin pain in young adults? snapping

Answer 35

femeroactetabular impingement

Question 36

CREST syndrome features?

Answer 36

calcinosis raynauds eosphageal dysmotility scelrodactyly telangectasia

Question 37

what abx should be avoided if on MTX?

Answer 37

co trim trimethoprim

Question 38

pagets features?

Answer 38

old man bone pain ALP rise

Question 39

osteomalacia features?

Answer 39

low Ca low P raised ALP raised PTH

Question 40

secondary hyperparathyroidism bloods?

Answer 40

high ALP high P high PTH renal disease

Question 41

what T score is diagnostic for osteoporosis?

Answer 41

-2.5

Question 42

when should a DEXA scan be repeated?

Answer 42

after 5 yrs bisphosphonates

Question 43

what is waiters tip palsy?

Answer 43

erb duchenne C5/C6 arm is IR, elbow extended

Question 44

what is klumpke injury?

Answer 44

C8 T1 claw hand (MCP extended, IP flexed)

Question 45

gestational diabetes Tx ladder?

Answer 45

diet metformin insulin (if metformin and diet not working)

Question 46

when should pregnant women get aciclovir?

Answer 46

>20 weeks within 24hrs of rash

Question 47

when should pregnant women get VZIG?

Answer 47

7-14 days post exposure

Question 48

Tx for lichen planus?

Answer 48

clobetasone butyrate

Question 49

ABPI for arterial disease?

Answer 49

<0.9

Question 50

Tx for keloids?

Answer 50

intralesional triamcinolone

Question 51

what drugs worsen psoriasis?

Answer 51

B blocker

Question 52

Tx for capillary haemangioma?

Answer 52

propranolol

Question 53

Tx for flexural psoriasis?

Answer 53

coal tar steroid

Question 54

features of lichen planus?

Answer 54

purple pruritis rash flexor surfaces wickhams striae oral