Deck 2

Question 1

-lukast

Answer 1

Antiasthmatic-Leukotriene Antagonists

• Montelukast* (Singulair)
• Zafirlukast (Accolate)

Question 2

What is the mode of action for Antiasthmatic-Leukotriene Antagonists (Montelukast, Zafirlukast)

Answer 2

Counteracts the effects of chemical mediators that cause bronchoconstriction and mucus production

Question 3

-nacin

Answer 3

Anticholinergics-Antimuscarinic

• darifenacin
• solifenacin

Question 4

What are Anticholinergic-Antimuscarcinic (darifenacin, solifenacin) used for?

Answer 4

To treat overactive bladder and urinary incontinence

Question 5

-rudin

Answer 5

Anticoagulant-thrombin inhibitor

• bivalirudin (Angiomax)
• desirudin (Iprivask)
• Lepirudin (rDNA)

Question 6

What drugs can increase the effects of Anticoagulant-thrombin inhibitor

Answer 6

Ginkgo Biloba
Garlic
Chamomile
licocrice root

Question 7

What drugs can decrease the effect of Anticoagulants

Answer 7

St. John Wort

Question 8

-gab, gaba-

Answer 8

Anticonvulsants (anti-seizure) GABA Analogue
-gabapentin& (neurontin)
-prebalin (lyrica)
tiagabine (gabitril)

Question 9

-toin

Answer 9

Anticonvulsant (anti-seizure) Hydantoins

• Ethotoin (Peganone)
• Fosphenytoin (Cerebyx)
• Phenytoin (Dilantin)

Question 10

What is Phenytoin used for?

Answer 10

Antiarrhythmia for preventing/blocking ventricluar arrhythmias

Question 11

-pramine

Answer 11

Antidepressants-Tricyclic Antidepressant (TCA)

• Despiramine (Norpramin)
• Imipramine (Tofranil)
• Trimipramine (Surmontil)

Question 12

What do Tricyclics (Desipramine, imipramine, trimipramine) do?

Answer 12

block the re-uptake of norepinephrine and serontonin

Question 13

What drug should not be given with Tricyclic drugs?

Answer 13

MAO- inhibitors

Question 14

How long until Tricyclic drugs take effect

Answer 14

3 weeks

Question 15

What are the side effects associated with Tricyclic drugs?

Answer 15

HATS: hypotension, anticholinergic effect, tachycardia and sedation

Question 16

-tyline

Answer 16

Antidepressants-Tricyclic (TCA)

• amitriptyline* (Elavil)
• nortriptyline (Pamelor)
• protriptyline (Vivactil)

Question 17

-citalopram

Answer 17

Antidepressants-Selective Serotonin Reuptake Inhibitors

• citalopram* (Celexa)
• escitalopram* (Lexapro)

Question 18

What is a common side effect of Antidepressants (-citalopraim)

Answer 18

weight gain 10lbs

Question 19

-oxetine

Answer 19

Antidepressants-Selective Serotonin Reuptake Inhibitors

• fluoxetine (Prozac)
• Paroxetine (Paxil)
• Duloxetine (Cymbalta)

Question 20

What is the mode of action for Cymbalta?

Answer 20

block the reuptake of both serotin and norepinephrine

Question 21

What is a common side effect of Antidepressants (-oxetine)

Answer 21

Nausea

Question 22

What are the possible side effects of discontinuing anti-depressants

Answer 22

flu-like sx
insomnia
imbalance
hyperarousal
sensory disturbances

Question 23

-setron

Answer 23

Antiemetics-serotonin 5-HT2 receptor antagonist
-alosetron
-dolasetron (Anzemet)
-granisetron (sancuso)
ondansetron (zofran)
palonosetron (aloxi)

Question 24

What are the side effects of Antiemetics ( -setron )

Answer 24

headache, constipation and diarrhea

Question 25

-iramine

Answer 25

Antihistamines - brompheniramine - chlorpheniramine - pheniramine

Question 26

What are common side effects of Antihistamines ( -iramine )

Answer 26

drowsiness dry mouth throat

Question 27

-pril

Answer 27

Antihypertensives-angiotensin converting enzyme (ACE) inhibitors - Banazepril* (Lotensin) - Captopril (Capoten) - Enalapril* (Vasotec) - Moexipril (Univasc) - quinapril (Accupril) - lisinopril* (Prinivil, Zestril)

Question 28

What is the most common side effects of ACE inhibitors

Answer 28

dry cough

Question 29

What must be monitored for when taking ACE inhibitors?

Answer 29

hyperkalemia because of decrease sodium reabsorption

Question 30

What is a possible adverse effect of ACE inhibitors?

Answer 30

Angioedema- starting at back of throat and progress. Can lead to cardiac arrest

Question 31

-azosin

Answer 31

Antihypertensive-Alpha Adrenergic blockers - doxazosin - prazosin - terazosin

Question 32

What is the mode of action for Alpha Adrenergic Blockers?

Answer 32

vasodilation- decreasing hypertension

Question 33

-dipine

Answer 33

Antihypertensive/Cardiovascular Drugs Calcium channel Blockers - amlodipine* (Norvasc, Lotrel) - felodipine (Plendil), - Isradipine (DynaCirc) - Nicardipine (Cardene) - Nifedipine (Adalat, Procardia) - Nimodipine (Nimotop)

Question 34

What are Antihypertensive Calcium Channel Blockers used for?

Answer 34

used to prevent or treat angina and hypertension

Question 35

What must be monitored for when taking Calcium channel blockers?

Answer 35

hypotension, worsening CHF, heart block

Question 36

What is the difference between "dipine" and "NON-dipine" calcium channel bockers?

Answer 36

"dipine" do not help treat supraventricular tachycardia, but NON do

Question 37

-sartan

Answer 37

Antihypertensive-Angiotenssin II receptor blockers - candesartan (Atacand) - irbesartan (Avapro) - iosartan (cozaar) - olmesartan* (benicar) - valsartan* (diovan)

Question 38

What is the mode of action for Angiotensin II receptor blocers?

Answer 38

block effects of angiotensin II at its receptor to decrease vasoconstriction and aldosterone

Question 39

When are ARBS used to treat HTN and heart failure?

Answer 39

when ACE inhibitors cannot be tolerated.

Question 40

When are ARBs contraindicted?

Answer 40

prego