Deck 7

Question 1

What is the antibiotics treatment regimen of choice for cystic fibrosis patients with Pseudomonas infection?

Answer 1

Ceftazidime and tobramycin

Question 2

What are some features of chronic lead poisoning?

Answer 2

Developmental delay
Abdominal pain
Blue line on gums
Constipation

Question 3

What are some clinical features of vestibular schwannoma?

Answer 3

Unilateral sensorineural hearing loss
Ipsilateral ataxia
Facial weakness
Trigeminal sensory loss

Question 4

What are some clinical features of vestibular schwannoma?

Answer 4

Unilateral sensorineural hearing loss
Ipsilateral ataxia
Facial weakness
Trigeminal sensory loss

Question 5

How is a low-dose dexamethasone suppression test performed?

Answer 5

1 mg dexamethasone at midnight

Measure serum cortisol at 9 am

Question 6

What is the difference between Wells, PERC and PESI?

Answer 6

Wells: Determine whether CTPA or D-Dimer would be required
PERC: Determine whether a PE is even a feasible possibility/requires further investigation
PESI: Determines mortality in people with a diagnosed PE

Question 7

Which marker is used as a screening test for fungal infections?

Answer 7

Beta-D Glucan

Question 8

At what point do you consider using negative suction to resolve a pneumothorax?

Answer 8

If a chest drain has failed to resolve the pneumothorax and there is a persistent air leak after 48 hours

Question 9

What causes TRALI?

Answer 9

Presence of anti-HLA antibodies in the donated blood product

Question 10

What are the Truelove and Witts criteria for a severe UC flare?

Answer 10

Bloody stools > 6 per day 
HR > 90
Temp > 37.8
Hb < 10.5
ESR > 30
CRP > 30

Question 11

What is an option for the treatment of severe hand eczema?

Answer 11

Alitretinoin

Question 12

Name a novel drug that is used to treat multiple sclerosis.

Answer 12

Fringolimod

NOTE: it is a sphingosine-1-phosphate receptor modulator which affects the activity of lymphocytes

Question 13

What is the most common cause of line-related sepsis?

Answer 13

Staphylococcus aureus

Question 14

What are some side-effects of phenytoin?

Answer 14

Ataxia
Nystagmus
Agitation
Drowsiness

(Cerebellar signs)

Question 15

How is exercise testing interpreted according to the Bruce protocol?

Answer 15

Patients who cannot undergo two stages of the Bruce protocol (< 6 mins) are at higher risk of adverse cardiovascular events and should be considered for coronary angiography.

Question 16

How do you dose amiodarone for cardioversion?

Answer 16

300 mg over 30-60 mins followed by 900 mg over 24 hours

Needs to be infused through a large cannula into a large peripheral vein or into a central vein as it can cause thrombophlebitis

Question 17

What should you do with metformin in someone who is going to undergo an angiogram?

Answer 17

Metformin should be held for 48 hours before and after any procedure involving IV contrast (e.g. CT scan, angiogram)

This is because it could increase the risk of lactic acidosis.

Question 18

How do you manage a relapse of multiple sclerosis?

Answer 18

Oral Methylprednisolone 0.5 g OD for 5 days

Question 19

Which medication is used as prophylaxis for patients who suffer cluster headaches?

Answer 19

Verapamil

Alternatives: lithium, sodium valproate, gabapentin

Question 20

Which type of myocardial infarction and rhythm disturbance would require temporary transvenous pacing?

Answer 20

Second or third degree heart block complicating an acute anterior MI