Flashcards in Definitions Deck (32):
In a living organism, the morphological changes that occur after a cell has been dead some time.
Programmed cell death, with shrinkage
Grossly visible necrosis
Area of dead tissue- necrosis caused by acute ischaemia
Fluid flow across vessels is determined by balance of hydrostatic and colloid osmotic pressure across plasma and interstitial fluid
Response of living tissue to injury - aims to protect body against infection.
Chronic response to injury with associated fibrosis
Chronic inflammation with granulomas
Cell responds to signalling molecules they produce
Cell synthesises a factor which binds to intracellular receptor in the cell- not secreted.
Cells produce signalling molecule that acts on adjacent cells
Hormone synthesised by cells in endocrine organ, conveyed in the blood stream to target cell.
The body's response to stop bleeding and loss of blood
Formation of a solid mass of blood within the circulatory system during life.
Blockage of a blood vessel by solid, liquid or gas at a site distant from its origin
Accumulation of intracellular and extracellular lipid in the intima and media of large and medium sized arteries
The thickening and hardening of arterial walls as a consequence of atheroma
The thickening of the walks of arteries and arterioles, usually as a result of hypertension or diabetes mellitus
Replacement of cell losses by identical cells to maintain tissue organ/size
Increase in tissue/organ see due to increased cell numbers
Increase in tissue/organ size due to increase in cell size
Shrinkage of a tissue/organ due to an acquired decrease in size &/or number of cells
Reversible change of 1 differentiated cell type to another
Complete failure of a specific tissue/organ to develop
Congenital! Underdevelopment/incomplete development of a tissue/organ. Inadequate number of cells within the tissues present (on a spectrum with Aplasia)
Abnormal maturation of cells within a tissue. Reversible. As pre-neoplastic alteration in which cells show disordered tissue/organ
Replacement of a lost body part. Requires coordinated responses of several types of cell
Normal programmed shrinkage of an organ
The abnormal growth of cells p, which persists after initiating stimulus has been removed. Irreversible.
Abnormal growth of cells which persists after initiating stimulus has been removed and invades surrounding tissue with potential to spread to distant sites.