Definitions

Question 1

Promoter

Answer 1

The DNA sequence at which the RNA polymerase (RNAP) binds, often used to include the entire regulatory region around a transcription start site

Question 2

Transcription Factor (TF)

Answer 2

A protein that binds to DNA sequences within or near the promoter. This may enhance or reduce transcription. The bacterial sigma factor or lac repressor can be thought of as transcription factors

Question 3

Initiation region (Inr)

Answer 3

The region around the Transcription Start Site (TSS): Site of initiation of transcription of an RNA (numbered +1, the position before it is -1)

Question 4

Transcription factor binding site (TFBS)

Answer 4

The binding site of a transcription factor

Question 5

Transcriptional regulation:

Answer 5

Regulation of transcription may be positive/induction/upregulation or negative/repressive/down-regulation