Dementia Flashcards

(39 cards)

1
Q

How many people are currently living in Scotland with dementia?

A

90,000

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2
Q

In DSM-5 what is ‘dementia’ replaced with?

A

Major Neurocognitive Disorder

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3
Q

Which of the following is conducted to asses dementia?

  • MRI
  • Neuro-imaging
  • Blood test
  • CSF sample examination
  • physical exam
  • cognitive exam
A
  • neuro imaging
  • csf sample
  • physical examination
  • cognitive examination
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4
Q

Neuro psychology adresses the link between:

  • Brain and emotions
  • Brain and Behaviour
  • Brain and memory
  • Memory and Behaviour
A

Brain and Behaviour

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5
Q

Name some domains examined when assessing for dementia?

A
Mood
Executive functions
Effort/Motivation
Language
Visuospacial Awareness
Attention
Memory
Premorbid Function
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6
Q

What is a CDR?

A

a Clinical Dementia Rating.

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7
Q

What is the GDS?

A

the Global Deterioration Scale:

  • A scale of 7 clinical stages.
  • Stages 1-4 range from normality to mild dementia.
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8
Q

What are the 5 pillars for management of dementia?

A
  • Supporting community connections
  • Peer support
  • Planning for future care
  • Understanding the illness/ managing symptoms
  • Planning for future decision making
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9
Q

who might be included in the multidisciplinary team supporting dementia?

A
  • SLT
  • OT
  • PT
  • GP
  • Neurologist
  • Psychiatrist
  • Palliative care team
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10
Q

Which of the following are pharmacological interventions for dementia?

  • Cholinesterase Inhibitors
  • Ginkgo
  • Anti-inflammatories
  • Antidepressants
  • Salvia
  • lithium
  • Antipsychotics
  • Aspirin
  • Oestrogen
  • Trazodone
A
  • Cholinesterase Inhibitors
  • Ginkgo
  • Antidepressants
  • Salvia
  • Antipsychotics
  • Trazodone
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11
Q

Examples of non-pharmacological intervention?

A
Cognitive Behavioural Therapy (CBT)
Multisensory Stimulation
Physical Activities
Arts therapy (music, art)
Validation therapy
Reminiscence therapy
Family/Caregiver Intervention Programmes
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12
Q

What are the 4 types of dementia?

A
  • Cortical
  • Subcortical
  • Mixed cortical/subcortical
  • Treatable
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13
Q

What type of dementia is Alzheimer’s disease?

A

Cortical.

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14
Q

What is the most common form of dementia?

A

AD

60-70% of dementia cases

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15
Q

What is the Amyloid hypothesis for AD?

A
  • Excess amyloid peptides clump together
  • Form diffuse plaques>
  • Plaques block neural pathways and cause an inflammatory process>
  • Inflammation can lead to formation of neuritic plaques
  • Causing synaptic and nueritic injury and cell death
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16
Q

Symptoms of AD?

A

-Symptoms include memory problems (recent)
-language problems (verbal fluency & word finding)
-visuospatial dysfunction
-deterioration in ability to perform basic tasks
-behavioural disturbance (aggression, wandering,
agitation, inappropriacy, apathy)

17
Q

Risk factors for AD?

A
Down’s syndrome
Advanced Age
Female
Genetic predisposition
History of TBI
Lifestyle Factors
18
Q

BEHAVIOURAL AND PSYCHOLOGICAL SYMPTOMS

OF ALZHEIMER’S DISEASE?

A
Anxiety
Agitation
Aggression
Wandering
Hallucinations
Delusions
Depression
19
Q

What is Mild Cognitive Impairment?

A

An intermediate stage in cognitive function between the natural changes of ageing and the progressive decline of dementia.

20
Q

What does MCI mostly affect?

A
  • Memory
  • Judgment
  • Language
  • Attention
21
Q

someone with MCI might also suffer with?

A
  • Depression
  • Anxiety
  • Irritability
  • Agression
22
Q

What is the prevalence of MCI?

23
Q

What is the risk for someone with MCI developing dementia?

A

11-33% over 2 years

24
Q

In vascular dementia what is most affected and what changes are seen earliest?

A
  • Executive functions more affected than memory

- Motor and mood changes spotted the earliest

25
How stable are symptoms for Vascular Dementia?
- Onset may be sudden (abrupt) | - There may be periods of sudden decline followed by stages of relative stability. (fluctuating course)
26
What vascular pathologies might occur in Vascular Dementia?
(to both white and grey matter) - Infarction - Ischemia - Haemorrhage - Small vessel changes (Leukoaraiosis)
27
- Damage to the capilaries (Protein leakage) - Loss of Axons. Myelin & Oligodendrocytes - Perivascular tissue loss are examples of?
Leukoaraiosis | Small vessel changes
28
How could you distinguish VD from AD?
Vascular dementia most likely to have: - Abrupt onset - Fluctuating course - History of stroke - Focal neurological symptoms and signs - Preserved recent memory - More diverse language profiles than AD - Test scores decline less than AD over time there is a high incidence of the two co-occuring
29
Prevalence of Dementia with Lewy Bodies?
10% of cases
30
- cognitive decline and day-to-day fluctuation - recurrent visual hallucinations - REM sleep behavioural disorder - Antipsychotic sensitivity - paranoia and delirium all are characteristics of?
Dementia with Lewy Bodies.
31
- Abrupt onset - Fluctuating course - History of stroke - Focal neurological symptoms and signs - Preserved recent memory are all characteristics of?
Vascular dementia.
32
DEMENTIA WITH LEWY BODIES years of survival after symptom onset: A. 7-10 years B. 5-9 years C. 5-7 years
C. 5-7 years
33
What is the second most common type of dementia?
FRONTOTEMPORAL | DEMENTIA
34
Typical age of onset for FTD is?
Typically appear in mid-life, mean age of onset 53-58
35
Gross changes in social behaviour and language: - indifference to self-care and others' needs - loss of speech and comprehension - loss of empathy - distractibility - impulsiveness & dis-inhibition - rigid routines & compulsions are typical for?
Fronto-Temporal Dementia.
36
LOOK AT FINAL SLIDE ON DEMENTIA/DELIRIUM
XXX
37
What are examples of other causes of dementia?
- HIV dementia - Huntington's Disease - Prion Disease - TBI - Substance induced major cognitive disorder
38
Treatable cause of dementia?
- Normal Pressure Hydrocephalus - Chronic Subdural Haematoma - Benign Tumour - Metabolic and Endocrine Disturbances - Infections
39
What is Delirium ?
An acute, reversible, metabolically induced state of fluctuating consciousness. Leeds to fluctuations in cognitive performance and behaviour. Disorder of perception, thinking and memory.