Derm

Question 0

ectoderm grows into

Answer 0

skin and nerves

Question 1

average weight of skin

Answer 1

4kg

Question 2

this skin layer protects a fetus from maceration

Answer 2

periderm

Question 3

desquamated cells of periderm form part of this white greasy substance

Answer 3

vernix caseosa

Question 4

purpose of vernix caseosa

Answer 4

protection of fetus from maceration in all those juices

Question 5

at 10 weeks, a fetus has

Answer 5

fingernails and toenails on fingers and toes (respectively)

Question 6

at 11 weeks, a fetus’ skin develops

Answer 6

melanoblasts, collagen and elastin

Question 7

at 12 weeks, a fetus’ melanocytes. . .

Answer 7

migrate to hair buds

Question 8

by the end of the first trimester

Answer 8

the majority of vascular organization is established

Question 9

by 17 weeks, a fetus’

Answer 9

epidermal ridges (fingerprints and such) are permanently established

Question 10

by 20 weeks, a fetus’ skin has developed

Answer 10

sweat glands

Question 11

lanugo hairs

Answer 11

help hold vernix caseosa on fetal skin

Question 12

vellus hairs

Answer 12

coarser than, and replace lanugo hairs

Question 13

at puberty, axillary and pubic regions. . .

Answer 13

coarse terminal hairs

Question 14

at 21 weeks

Answer 14

replacement of periderm stops, giving rise to stratum corneum

Question 15

at 23 to 28 weeks

Answer 15

neural crest cells migrate into mesenchyme and differentiate into melanoblasts

Question 16

4 components of skin

Answer 16

Epidermis
Dermis
Skin Appendages
Subcutaneous Fat

Question 17

list layers of epidermis from deepest to surface

Answer 17

Stratum Basale
Stratum Spinosum
Stratum Granulosum
Stratum Corneum

Question 18

Purpose of Stratum Basale

Answer 18

Cell division and differentiation

Question 19

Keratinocyte AKA

Answer 19

Corneocytes

Question 20

The stratum ________ is a barrier for entry

Answer 20

corneum

Question 21

Time from basal layer to granular layer

Answer 21

2 weeks

Question 22

Time from granular layer to desquamation

Answer 22

2 weeks

Question 23

cells divide in

Answer 23

basal layer

Question 24

4 types of cells in epidermis

Answer 24

Keratinocytes Melanocytes Langerhans cells Merkel cells

Question 25

Stratum Corneum AKA

Answer 25

Horny Layer

Question 26

Stratum Granulosum AKA

Answer 26

Granular Layer

Question 27

Stratum Spinosum AKA

Answer 27

prickle cell layer

Question 28

Stratum Basale AKA

Answer 28

Basal Cell Layer

Question 29

Diseases from keratinocytes

Answer 29

squamous cell and basal cell carcinomas

Question 30

Melanocytes gone bad

Answer 30

melanoma

Question 31

langerhans cells serve in

Answer 31

immunity

Question 32

Merkel cells are ______ for _______

Answer 32

Merkel cells are transducers for fine touch

Question 33

3 layers of basement membrane

Answer 33

Lamina Lucida Basal Lamina Anchoring Fibrils

Question 34

too much friction on basement membrane causes

Answer 34

blisters

Question 35

Dermis contains

Answer 35

Collagen Elastin Extra fibrillar matrix

Question 36

skin appendages

Answer 36

``` eccrine sweat glands Aprocrine sweat glands hair follicles sebaceous glands nails ```

Question 37

eccerine sweat glands

Answer 37

coiled tubule deep in dermis, like little kidneys, go from isotonic to hypotonic due to ductal reabsorption

Question 38

apocrine sweat glands, define and where?

Answer 38

make you stink, pheromones, useless-ish, only in the danger zones

Question 39

where are there no hair follicles

Answer 39

palms and soles, and some parts of my junk

Question 40

Anagen phase of hair growth

Answer 40

growth phase

Question 41

Rate during anagen phase

Answer 41

1 cm per month

Question 42

% of scalp hairs in anagen

Answer 42

80-90

Question 43

catagen phase of hair growth

Answer 43

resting phase

Question 44

catagen phase lasts

Answer 44

3-4 weeks

Question 45

preggers hang out in this hair phase

Answer 45

catagen

Question 46

duration of anagen phase for scalp / eyebrows

Answer 46

3-7 years / 4 months

Question 47

telogen phase of hair growth

Answer 47

shedding phase

Question 48

notable characteristic of hairs in telogen phase

Answer 48

short club root

Question 49

Number of scalp hairs shed in telogen phase / day

Answer 49

50-100

Question 50

% of scalp hairs in telogen

Answer 50

10-20

Question 51

% scalp hairs in catagen

Answer 51

1

Question 52

Ten Functions of skin

Answer 52

barrier, injury protection, prevent dehydration, shield UV, regulate temp, grip surface, sensory organ, immune surveillance, vitamin D production, makes us look pretty

Question 53

4 questions to start a derm exam with

Answer 53

how long? Where? Does it itch? How have you treated it?

Question 54

Itchy, think

Answer 54

histamine

Question 55

burny, think

Answer 55

nerve

Question 56

big severity question

Answer 56

does it keep you awake at night?

Question 57

Three factors of good derm physical

Answer 57

Undress completely, good lighting, look everywhere

Question 58

list topical preparations

Answer 58

``` Gels Cream Lotion Ointments Pastes and Powders Dressings ```

Question 59

creams can be good for

Answer 59

drying out

Question 60

ointments help to

Answer 60

Hydrate

Question 61

how to potentate an ointment

Answer 61

occlude

Question 62

adverse effects of topical steroids

Answer 62

skin atrophy | papular or perioral dermatitis

Question 63

avoid high potency steroids on

Answer 63

genital or face

Question 64

List melanoma types

Answer 64

``` SNALL Superficial spreading Nodular Acral lentiginous Lentigo maligna ```

Question 65

Most common melanoma

Answer 65

Superficial spreading

Question 66

Melanoma signs

Answer 66

``` ABCD(E) Asymetry Border irregularity Color variation Diameter >6mm Elevation ```

Question 67

Where am I likely to find acral lentiginous melanoma

Answer 67

Palms, soles and distal fingers and toes