Derm 4 - Inflammatory skin conditions Flashcards Preview

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Flashcards in Derm 4 - Inflammatory skin conditions Deck (31):
1

Which chronic inflammatory skin disorders follow a relapsing and remitting course?

- Eczema
- Psoriasis
- Acne

2

What is the most common type of eczema?

Atopic eczema

3

Which chronic inflammatory skin condition is characterised by papule and vesicles on an erythematous base?

Atopic eczema

4

Name some triggers for atopic eczema:

- Infection
- Chemicals
- Food
- Dust
- Pet fur
- Sweating
- Heat
- Stress

5

What commonly presents as itchy, scaly dry erythematous patches, on flexor aspects of limbs?

Atopic eczema

6

Where does atopic eczema commonly affect the body in infants and adults?

Infants - Face and extensor aspects of limbs
Children/adults - Flexor aspects of limbs

7

Chronic scratching/ rubbing of atopic eczema can lead to what skin changes?

Excoriation
Lichenification

8

How would you treat mild atopic eczema?

- Trigger avoidance
- Freq emollients
- Soap substitute
- Topical hydrocortisone

9

How would you treat severe atopic eczema with secondary bacterial infections?

- Trigger avoidance
- Freq emollients
- Soap substitute
- Topical betamethasone
- Flucloxacillin

10

Which topical immunomodulators can be used as steroid-sparing agents in atopic eczema?

- Tacrolimus
- Pimecrolimus

11

What treatment can you try for severe non-responsive cases of atopic eczema?

- Phototherapy
- Immunosuppressants: oral prednisolone, azathioprine, ciclosporin

12

Name the complication of atopic eczema caused by infection of herpes simplex virus:

Eczema herpeticum

13

What is the ladder of topical steroid therapy for atopic eczema?

Mild - hydrocortisone
Mod - Clobetasone
Potent - Betamethasone
V potent - Clobetasol

14

Name the inflammatory disease of pilosebaceous follicles:

Acne vulgaris

15

What is the cause of acne vulgaris?

Androgens

16

What kind of acne is described as non-inflammatory lesions with open and closed comedones?

Mild acne vulgaris

17

What kind of acne is described as inflammatory lesions with papule, pustules, nodules and cysts?

Mod/severe acne vulgaris

18

What are the topical therapies for acne vulgaris?

- Benzoyl peroxide
- Abx - Erythromycin
- Retinoids - Tretinoin

19

What are the oral therapies for acne vulgaris?

- Abx - Tetracyline
- Anti-androgens - Co-cyprindiol
- Retinoids - Isotretinoin

20

Name some complications of acne vulgaris:

- Scarring
- Hyperpigmentation
- Deformity
- Physiological and social effects

21

What condition is benzoyl peroxide used in?

Acne vulgaris

22

Which antibiotics are usually used for acne vulgaris?

Topical - Erythromycin
Oral - Tetracycline

23

A chronic inflammatory skin condition due to hyperproliferation of keratinocytes and inflammatory cell infiltration...

Psoriasis

24

Name the 6 types of psoriasis:

- Plaque
- Guttate
- Sebhorrheic
- Flexural
- Pustular
- Erythrodermic

25

What is the most common type of psoriasis?

Chronic plaque psoriasis

26

How does plaque psoriasis present?

- Well-demarcated erythematous plaques with silvery scales
- Itchy, burning, painful
- Extensor surfaces (of children/adults)

27

What nail changes are associated with psoriasis?

- Oncholysis
- Nail pitting

28

What are some features of psoriatic arthritis?

- Joint pain and stiffness
- Dactylitis
- Spondylitis
- Achilles tendonitis
- Enthesitis
- Uveitis

29

List some topical therapies for psoriasis:

- Emollients
- Vitamin D analogues
- Topical corticosteroids: hydrocortisone
- Coal tar preparations
- Dithranol
- Topical retinoids: Tretinoin
- Keratolytics: salicylic acid
- Scalp preparations

30

What treatments are available for extensive severe psoriasis?

- Phototherapy
- Oral immunomodulators: Methotrexate, ciclosporin, mycophenolate mofetil
- Oral retinoids: Isotretinoin
- Biologicals: Infliximab, Etanercept, Efalizumab

31

What are the complications of psoriasis?

- Erythoderma
- Psychological and social effects