DERM

Question 1

flat, circumsized region of skin w/different color or texture

Answer 1

macule

Question 2

large macuole

Answer 2

patch

Question 3

can feel, look abnormal, example is acne

Answer 3

papule

Question 4

larger lesions of papules

Answer 4

plaques

Question 5

clear fluid filled lesion-blister

Answer 5

vesicle

Question 6

definition of neoplasia

Answer 6

uncontrolled cell growth

Question 7

neoplasm w/no capability for metastasis

Answer 7

benign

Question 8

has the potential for metastasis

Answer 8

malignant

Question 9

malignant neoplasm

Answer 9

cancer

Question 10

what is classified by the presence or absence of invasion past basement membrane into foreign tissue

Answer 10

epithelial neoplasm

Question 11

what does IN SITU mean

Answer 11

benign (still located within the epidermis)

Question 12

name of benign melanocytic neoplasm

Answer 12

nevi

Question 13

benign neoplasms of melanocytes that everyone has

Answer 13

common/junction acquired or congenital

Question 14

acquired nevi that starts within the epidermis

Answer 14

junctional

Question 15

acquired nevi that starts within Dermal

Answer 15

compound

Question 16

congenital nevus

Answer 16

very large, especially in kids

Question 17

benign nevus that must always be cut off since some melanomas can resemble, red dome shaped commonly on cheak of child

Answer 17

spitz

Question 18

starts in the dermis and can be commonly mistaken for melanoma (papule and dark)

Answer 18

blue nevus/dermal melanocytoses

Question 19

clinically concerning nevi that has immune reaction so there’s white around mole

Answer 19

halo

Question 20

dysplastic nevi

Answer 20

risk marker for melanoma - tends to be familial inherited

Question 21

ABCD

Answer 21

asymmetry

Question 22

Epithelial neoplasms

Answer 22

seborrheci keratosis

Question 23

very common, and can develop into benign squamous epithelium. All is in the epidermis. Most people who have them have a ton.

Answer 23

Actinic keratosis

Question 24

scaly red papule that’s raised. Sun related.

Answer 24

Squamous cell carcinoma

Question 25

SCCIS

Answer 25

benign- contained in basement membrane

Question 26

SCC

Answer 26

malignant- invades basement membrane and dermis

Question 27

Can you shave squamous cell carcinoma

Answer 27

yes, depth doesn't matter as much

Question 28

most common human malignancy that is slow growing. can rarely metastasize. Present w/pearly papule.

Answer 28

basal cell carcinoma

Question 29

type of epithelial neoplasm that can differentiate toward hair follicles, eccrine, sebaceous, or apocrine glands

Answer 29

adnexal

Question 30

syndrome that has multiple trichilemmonas (face), visceral carcinomas, cerebral lesions, macrocephaly

Answer 30

Cowden syndrome

Question 31

mutation that causes cowden syndrome

Answer 31

PTEN (tumor suppressor gene)

Question 32

Muir torre syndrome has...

Answer 32

mutations in DNA mismatch repair proteins

Question 33

how does muir torre syndrome manifest

Answer 33

sebaceous neoplasms

Question 34

T/F. You can shave sebaceous proliferations.

Answer 34

False, you must get to the deeper part of the lesion.

Question 35

rare, very aggressive epithelial cancer that has poor prognosis

Answer 35

merkel cell carcinoma

Question 36

what causes merkel cell carcinoma

Answer 36

polyomavirus

Question 37

stromal neoplasms

Answer 37

dermatofibroma

Question 38

common in younger women, has tan/brown papule on legs, do pinch test

Answer 38

Dermatofibroma

Question 39

how do you biopsy dermatofibromas?

Answer 39

deep shave underneath - you can't just knick the top

Question 40

DFSP - dermatofibrosarcoma protuberans

Answer 40

poorly defined plaque on the buttox of lower legs

Question 41

proliferation of blood vessel in the dermis neoplasm, benign

Answer 41

Hemangioma

Question 42

common in kids and pregnant women but can be shaved off

Answer 42

pyogenic granuloma

Question 43

malignant vascular neoplasm caused by virus

Answer 43

kaposi sarcoma

Question 44

what virus causes karposi sarcoma

Answer 44

human herpes virus 8

Question 45

how do you biopsy karposi sarcoma

Answer 45

punch - need deeper

Question 46

bad, malignant vascular tumor that comes from sun damaged skin

Answer 46

angiosarcoma

Question 47

common benign peripheral nerve sheath tumor

Answer 47

neurofibroma

Question 48

where does cutaneous T cell lymphoma occur

Answer 48

non sun exposed areas (bathing suit distribution)

Question 49

where does the common type of T cell lymphoma occur...area of skin

Answer 49

epidermis (surface of skin)

Question 50

how does cutaneous B cell lymphoma present

Answer 50

single nodule on the head/face/neck

Question 51

where is cutaneous B cell lymphoma found?

Answer 51

deep dermis - punch biopsy is needed

Question 52

what is the best predictor for malignant melanoma

Answer 52

depth of invasion (breslow depth)

Question 53

what is used to measure breslow depth

Answer 53

millimeters

Question 54

what has a greater change of survival

Answer 54

less than 1.0 mm depth (stage 1)

Question 55

what can also be used to predict melanoma?

Answer 55

ulceration (ulcerated behave more poorly)

Question 56

do shave biopsies for..

Answer 56

most basal cells

Question 57

do punch biopsies for...

Answer 57

nodular basal cell carcinoma