Derm management Flashcards

(30 cards)

1
Q

Chronic psoriasis plaque management

A

Topical corticosteroids + Vit D analogue (calcipotriol, calcitriol, tacalcitol) 1x daily 4 wks
4 week break
2nd line - vit D analogue 2x daily
4 week break/no improvement
3rd line - Potent steroid 2x daily / coal tar prep 2x daily

Secondary care
Phototherapy - Narrow band UVB light 3x/wk/PUVA - risk of SCC

Oral methotrexate - if joint involvement

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2
Q

Mx scalp psoriasis

A

Topical corticosteroids - 1x daily 4/wk
no improvement after 4wks - use different preparation

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3
Q

Face, flexural, genital psoriasis mx

A

mild/moderate corticosteroid use 1/2 x daily for 2 weeks

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4
Q

Exacerbations of plaque psoriasis

A

Trauma
Alcohol
Drugs:
Beta-blockers
ACEi
NSAIDs
Li
Antimalarials

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5
Q

Tinea Corporis (fungal skin infection by dermatophytes) mx

A

trial of antifungal - terbinafine
no improvement - take scrapings

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6
Q

Exacerbations of acne rosacea

A

Sunlight
Alcohol
Exercise

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7
Q

When to do excisional biopsy?

A

Atypical lesion suspicion of melanoma
Need adequate margins

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8
Q

What condition may predispose to SCC on genitals?

A

Lichen Sclerosis

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9
Q

Pyoderma gangrenosum mx

A

Oral steroids
Ciclosporin + infliximab difficult cases

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10
Q

Associations of pyoderma gangrenosum

A

IBD
Rheum - SLE/RA
Haematological - myeloproliferative disorders, lymphoma, myeloid leukaemia
Primary biliary cirrhosis

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11
Q

Features pyoderma gangrenosum

A

Lower limbs typically
Sudden onset - begins as small pustule, red bump, blood blister
Skin ulcer with purple edges
May see gas/ muscle pain/deep ulceration

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12
Q

Which condition is associated with isoniazid use?

A

Pellagra

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13
Q

Pellagra?

A

Niacin deficiency
Diarrhoea, dermatitis, dementia
Common in alcoholics

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14
Q

Associations of Seborrhoeic dermatitis?

A

HIV
Parkinson’s

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15
Q

Features of sebhorrhoeic dermatitis?

A

eczematous lesions in nasolabial folds, auricular folds, scalp, around eye
Otitis externa
Blepharitis

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16
Q

Mx seborrhoeic dermatitis?

A

Scalp mx:
Zinc pyrithione - head + shoulders
Tar
2nd line = Ketoconazole

Body mx:
Ketoconazole
Topical steroids - short periods

17
Q

What is seborrhoeic dermatitis?

A

Inflammatory reaxn to fungal multiplication in skin
Malassezia furfur

18
Q

Common site of venous ulceration

A

Medial malleolus

19
Q

Mx venous ulceration

A

4-layer compression bandaging
Oral pentoxyphylline - vasodilator improves healing rate

20
Q

Ix in venous ulceration

A

ABPI - to ensure can go through with compression + assess arterial flow which may inhibit healing

21
Q

Cause of 90% fungal nail infection

A

Trichophyton rubrum
10% - candida infections

22
Q

Features + mx fungal nail

A

Rough, opaque nail

mx - nothing if pt ok
>50% damage, >2 nails, white - give amorifine 5% nail laquer
extensive damage - oral terbinafine
candida - oral itraconazole

23
Q

Acne rosacea mx

A

redness = topical brimonidine gel
Mild/moderate disease
1st line = topical ivermectin //metronidazole, azelaic acid
Severe
topical ivermectin, oral doxycycline

24
Q

Mx for scabies

A

Pt + all close contacts - topical 5% permethrin - 2x in different weeks
leave on for 8-12 hrs before washing
2nd line - malathione 0.5%
itchiness continues 4-6wks later

25
Scabies features
Linear burrows - interdigital webs, sides of fingers, flexor aspect of wrist Widespread itching
26
What is associated w/ Norwegian scabies? + mx
HIV/immunosuppression Mx - ivermectin
27
What is Nikolsky's sign?
Separation of dermis with application of mild lateral pressure
28
Drugs causing toxic epidermal necrolysis
Allopurinol Phenytoin NSAIDs Carbamazepine Penicillin Sulphonamides - sulfasalazine
29
Mx of toxic epidermal necrolysis?
IVIg
30
Actinic keratosis mx
Diclofenac, 5-fluorouracil, imiquimod