Dermatology Flashcards
Topical agent for pruritus-associated with atopic dermatitis or lichen simplex chronicus
Doxepin
Residual drug persists up to ____ days following application of permethrin.
10 days
It is recommended that permethrin 1% cream rinse (Nix) be applied undiluted to affected areas of pediculosis for ________ and then rinsed off with warm water.
10 minutes
This is available for the treatment of external genital and perianal warts in adults, actinic keratoses on the face and scalp, and biopsy-proven primary superficial basal cell carcinomas on the trunk, neck, and extremities.
Imiquimod
The mechanism of this drug’s action is thought to be related to its ability to stimulate peripheral mononuclear cells to release interferon alpha and to stimulate macrophages to produce interleukins-1, -6, and -8, and tumor necrosis factor-α (TNF-α).
imiquimod
Imiquimod should be applied to the wart tissue ________ times per week and left on the skin for ________ hours prior to washing off with mild soap and water.
three times a week
6–10 hours
Treatment with imiquimod should be continued until eradication of the warts is accomplished, but not for more than a total of _____ weeks.
16
Treatment of superficial basal cell carcinoma with imiquimod consists of ____-times-per-week application of 5% cream to the tumor, including a 1 cm margin of surrounding skin, for a ______ course of therapy
five times per week
6-week course
Maximum duration of prescribing potent topical steroids
2 weeks
This is an oral phosphodiesterase 4 (PDE4) inhibitor that is effective in treating moderate to severe plaque psoriasis.
Apremilast
This is a synthetic vitamin D3 derivative (available as a 0.005% cream, scalp lotion, and foam) that is effective in the treatment of plaque-type psoriasis vulgaris of moderate severity
Calcipotriene (Dovonex, Sorilux)
What are the superpotent TCS?
Clobetasol propionate 0.05%
Betamethasone dipropionate 0.05%
Class VII TCS
Hydrocortisone and Methylprednisolone
TCS Class of Desonide 0.05%
Class VI (mild)
Minoxidil side effects should be monitored especially for those with _____ disease
cardiac
This is available as a 1% shampoo or lotion for pediculosis capitis or pubis
Lindane
For pediculosis capitis or pubis, 30 mL of Lindane shampoo is applied to dry hair on the scalp or genital area for _____ minutes and then rinsed off.
4 minutes
_________, N-ethyl-o-crotonotoluidide, is a scabicide with some
antipruritic properties
Crotamiton
This is a straight-chain saturated dicarboxylic acid that is effective in the treatment of acne vulgaris and acne rosacea, and it also inhibit conversion of testosterone to DHT
Azelaic acid
This temporarily eliminates S aureus nasal carriage by patients or health care workers, but results are mixed with respect to its ability to prevent subsequent staphylococcal infection.
Mupirocin
This is a semisynthetic pleromutilin derivative effective in the treatment of uncomplicated superficial skin infection caused by group A β-hemolytic streptococci and S aureus, excluding MRSA.
Retapamulin (Altabax)
BID x 5 days
This is derived from the sap of the Euphorbia peplus plant and has recently been approved for the topical treatment of actinic keratoses. Local skin reactions are to be expected with crusting, swelling, vesiculation, and possible ulceration.
Ingenol mebutate
This is an α2-adrenergic agonist indicated for the topical treatment of persistent facial erythema of rosacea in adults 18 years of age or older.
Brimonidine (Mirvaso)
This is a metabolite of the aromatic retinoid etretinate, is effective in the treatment of psoriasis, especially pustular forms. It is more teratogenic than isotretinoin and must be discontinued for 3 years prior to conception.
Acitretin (Soriatane)
Used for treatment of pediculosis capitis of patients age > 6 months
Benzyl alcohol
