Dermatology Flashcards

(47 cards)

1
Q

Erythema toxicum neonatorum

A

Transient, benign, polymorphous skin rash of infancy.

Erythematous macules followed by wheals, vesicles, and sometimes pustules.

Palms and soles spared

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2
Q

Incidence, risk factors and typical age for erythema toxicum neonatorum

A

Occurs in 50-60% of newborns
More common in full-term/post-term infants and those with >2500g birth weight
Usually appears 24-48 hours after birth and resolves in 5-7 days

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3
Q

Acne neonatorum: definition and management

A

A new vulgaris appearing in the first 2-6 weeks of life, presumably 2/2 maternal and neonatal androgens

Self-limiting, occurs in 20% of infants

“6-week rash”

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4
Q

Port wine stain

Possible complications and associated conditions

A

Lesions covering entire half of face or bilateral face may be associated with Sturge Weber syndrome (neuro-ocular manifestations)

Hypertrophy Of soft tissue and bone with extremity lesions

Lesions on back, particularly crossing midline, associated with spinal/vertebral malformations

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5
Q

Port wine stain management

A

Refer to dermatologist early. Pulsed dye laser treatment recommended early in infancy, definitely before 1 year

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6
Q

Growth pattern for capillary hemangioma

A

Rapid growth beginning at birth and peaking around 6 months.
Involution begins between 9-12 months
10% resolution per year (10% at 1 year, 50% at 5 years, etc)

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7
Q

Complications of hemangiomas

A

Depth rather than size determines risk
Very deep may cause cardiovascular compromise
Thrombocytopenia may occur from platelet sequestration
Visual disturbance with orbital/eyelid/periorbital
Occult hepatic hemangiomas possible
Head/face lessons carry risk if subglottic lesion with airway compromise (hoarseness and stridor rapidly worsening in first weeks of life)
Ulceration as involution occurs

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8
Q

Lesions concerning for neurofibromatosis or Albright syndrome

A

Cafe au lait spots that are > 1.5cm or 6 or more in number

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9
Q

Risk factors for malignant melanoma development

A

Sunburn and excessive exposure prior to 10yoa

Family history

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10
Q

Albinism management

A

Sun protection counseling
Derm referral for skin changes
Ophtho referral for vision assessment

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11
Q

Vitiligo

Definition

A

Acquired autoimmune destruction of melanocytes resulting in hypopigmented areas on skin, oral mucosa and genitalia

Segmental- unilateral, 2 dermatomes
Generalized- >2 dermatomes, often bilateral

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12
Q

Vitiligo management

A

Sun protection
Topical steroids
Topical tacrolimus (inhibits T-cels)
Derm referral for other therapies

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13
Q

Psoriasis definition

A

Acquired inflammatory disorder with chronic relapsing-remitting pattern of erythematous plaques With silver-grey-white scales

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14
Q

Psoriasis guttate

A

Small patches primarily on trunk, upper arms and thighs

Often follows strep infection

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15
Q

Psoriasis vulgaris

A

Large plaques primarily on elbows and knees

Often associated with constant rubbing and trauma, “Koebner’s response”

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16
Q

Psoriasis management

A

Controlled and limited sunlight exposure
Topical corticosteroids
At least BID moisturizer or mineral oil

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17
Q

Atopic derm

Etiology/incidence

A

Disorder of skin barrier function, chronic forms often associated with filaggrin mutation and deficiency. Some associated with high IgE levels and altered immune function

10-15% incidence
Up to 50% develop other atopic disease
Up to 25% have symptoms that persist into adulthood

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18
Q

Dermatitis management

A

Topical steroids, oral antihistamine for pruritis, topical antibiotic for secondary infection

Diaper/atopic: emollients

Seborrheic: antiseborrheic shampoos, mineral oil, topical steroids, or topical salicylic acid. Some infants benefit from topical ketoconozole (melasezzia species may play too in etiology)

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19
Q

Burn classification

A

Superficial: epidermis only; erythema, edema, and dry tenderness
Partial-thickness: involve epidermis and part of dermis; includes moist areas and blisters
Full-thickness: Epidermis, dermis, and dermal appendage involvement; white, brown, black, swollen, dry areas with loss of sensation

20
Q

Define minor burn

A

Less than 10% BSA for superficial burns

Less than 2% BSA for partial- or full-thickness

21
Q

Define major burn

A

More than 10% BSA for superficial burns
More than 2% BSA for partial- or full-thickness burns
Any burns of hands, feet, face, eyes, ears, and perineum, regardless of BSA involved

22
Q

Burn diagnostics

A

Electrolyte studies, especially if burn is extensive

Culture of secondary infections

23
Q

Burn management - when to admit

A

Inpatient admission for all major burns, suspected abuse, esophageal or airway burns, or concomitant injuries (i.e. fractures)

24
Q

Outpatient burn management

A

Cool compresses
Pain control - acetaminophen or ibuprofen
Prophylactic antibiotics on open blistered areas (mupirocin or silver sulfadiazine [don’t use on face])
Push fluids for hydration
Topical emollients to repair and maintain barrier

25
Recommended SPF for children
greater than 30, apply 20 minutes before exposure
26
Cellulitis - common pathogens
Strep H. influenzae S. aureus MRSA
27
Cellulitis management
Burrow's solution compresses Topical antibiotics - mupirocin Oral abx: Staph- cephalexin or dicloxacillin Strep - amoxicillin, cehazolin, nafcillin H. flu - augmentin MRSA- Bactrim or clindamycin
28
impetigo - pathogens
``` Staphylococcus aureus (most common) Streptococci ```
29
Impetigo management
Topical mupirocin for most cases Oral abx for extensive disease, entire family affected, athletes, daycare: cephalexin or dicloxacillin Use amoxicillin if strep suspected Use bactrim or clinda if MRSA suspected
30
Staphylococcal Scalded Skin syndrome | Definition
Toxin-mediated systemic bacterial infection with skin manifestations. Caused by toxin produced by S. aureus
31
Staphylococcal Scalded Skin syndrome | presentation
Abrupt onset fever and malaise Generalized erythema and swelling, particularly perioral, periorbital, elbows, knees, groin, and axilla Light pressure causes pain and desquamation Vesicles and bullae
32
Staphylococcal Scalded Skin syndrome | Diagnostics
Blood culture or secretion culture to confirm S. aureus
33
Staphylococcal scalded skin syndrome | management
Hospitalize all neonates and sever cases for IV abx | Mild cases with stable environment: outpatient cefazolin or dicloxacillin, encourage fluids, fever and pain control
34
Acne vulgaris, mild - treatment
First line: Either BP or topical retinoid, or a combination of the two. May add topical antibiotic in fixed-ratio combination therapy Alternate: topical dapsone
35
Acne vulgaris, moderate - treatment
First line: Combo therapy containing BP + retinoid and/or antibiotic -or- PO antibiotic + BP + retinoid +/- topical abx Alternate: consider adding OCP or isotretenoin
36
Acne vulgaris, severe - treatment
Likely requires derm referral First line: PO abx + combo therapy with BP + retinoid + topical abx -or- PO isotretenoin Alternate: Consider OCP, spirinolactone in older teens
37
Topical abx in acne vulgaris
not recommended as monotherapy due to high resistence
38
PO abx in acne vulgaris
Extended release minocyline only FDA approved abx; use in kids >12yoa Tetracycline and doxycycline also used
39
Viral warts - treatment
salicylic acid and occlusive tape
40
pyogenic granuloma | definition and management
lobular capillary hemangioma - bleed easily | treatment required, either shave excision and cautery or surgical removal
41
Tinea versicolor
Macules/patches that are hypo- or hyperpigmented, or erythematous; caused by Malassezia species treat with topical ketoconozole or selenium sulfide Repigmentation may take months
42
Tinea corporis - presentation/management
Pruritic, erythematous, annular patch with central clearing and scaly raised border. Topical terbinafine or azole antifungals
43
Tinea capitis - management
Topicals ineffective, requires PO griseofulvin for 10-12 weeks and terbinafine for 6 weeks. Selenium sulfide shampoo may shorten length of fungal shedding and reduce familial infection
44
Telogen effluvium
Most common cause of diffuse hair loss Mature hair follicles switch prematurely to telogen (resting) state then shed within 3 months Typically occurs after major stress (pregnancy, surgery, major illness, severe weight loss) Self-limited with regrowth over a few months
45
Transient Neonatal Pustular Melanosis
Self-limiting condition most common in full-term infants with darker skin pigment. Pustules erupt to leave an erythematous or hyperpigmented macule with collarette of scale. Macules fade over a few months
46
Pityriasis Alba - description
``` Acquired condition Scaly, hypopigmented macules Indistinct borders Various shapes/sizes Primarily on cheeks ```
47
Pityriasis alba - clinical course
May be pruritic or erythematous Exacerbated by sunlight Spontaneous resolution in 3-4 months Moisturize and protect from sunlight