Dermatology Flashcards Preview

MSK & Connective Tissue > Dermatology > Flashcards

Flashcards in Dermatology Deck (21)
Loading flashcards...
1

SUN UV
DNA Pyridine dimers...
- Repair by Nucleotide Excision Repair
DNA polymerase in G1..

this is defective in...

Xeroderma Pigmentosum
"photosensitivity and Skin cancer in young"

2

Intensely pruritic on the flexor surface of the wrist, lateral surface of the finger, and finger webs
WORSE AT NIGTH

Sarcoptes scabei

- Permethrin and wash clothes

3

erythematous hyperkeratosis covered by silver scale
Pinpoint bleeding (sign?)
mildly pruritic
Koebner phenomenon
parakeratosis and cubed rete ridges

Psoriasis
--Auspitz sign!

+ stratum spinosum
- stratum granulosum

4

IgG ab DESMOSOMES (desmoglein 1-3)
Flaccid bullae
ORAL MUCOSA affected
- new blisters form w/gentle traction
- bullae spread laterally when applied pressure
IF ¿?

Pemphigus Vulgaris (+fatal)
-
Nikolsky +
Asboe-Hansen sign +

IF: RETICULAR

5

IgG ab HEMIDESMOSOMES
TENSE blisters
NO oral compromise

IF?

Bullous Pemphigoid

IF: LINEAR

6

+ common skin cancer
sun-exposed
waxy pink pearly nodules - nonhealing ulcers
-· Palisading of Nuclei

Basal Cell carcinoma

7

premalignant lesions by sun expousure
Small, ROUGH, papules or plaques w/scale
hyperkeratosis & parakeratosis & Keratinocite atipia
-- RISK ok SQUAMOUS CELL CARCINOMA

Actinic Keratosis

8

6P
INFILTRATE OF LYMPHOCYTES at the dermal-epidermal junction
Thickened of stratus GRANULSOSUS with sawtooth rate ridges
Wickham Striae- reticular withe lines
associated with hepatitis C

Priritic, Purple/Pink, Polygonal, Planar Papules and Plaques

LICHEN PLANUS

9

flat greasy pigmented
Looks "Stuck on" & waxy
Horn cyst - microscope: keratin containing cyst

Rapid onset...

SEBORRHEIC KERATOSIS

Rapid onset... LASER-TRELAT sign: malignancy (GI)

10

Skin: ·Target Lesions·
ass. w/ Herpes, mycoplasma, and Sulfas
T-cells

Erythema Multiforme

11

INTENSE PRURITIC eruption
associated w/asthma & allergic
mutation in the filaggrin gene (skin barrier dysfunction)
face on infants or antecubital fosa
High IgE / eosinophilia

Atopic Dermatitis
ECZEMA

12

Depigmentation
Absence of Melanocytes
associated with other autoimmune

VITILIGO

13

Most common benign vascular tumor in children?
strawberry-like bright red compressible plaques

Capillary hemangioma

14

Acanthosis nigricans
associated w/
-
-

Insulin resistance (DBT, obesity, Cushing, PCOS)
Visceral malignancy (gastric adenocarcinoma)

15

Type IV Hypersensitivity
erythematous papulovesicular weeping lesions
SPONGIOSIS & EDEMA FLUID

ALLERGIC CONTACT DERMATITIS

16

Chronic lymphedema risk of developing...

Cutaneous Angiosarcoma

Steward-Treves Sindome

17

Cutibacterium acnes colonize ...

Pilosebaseous follicles

anaerobic lipid-rich environment

18

defective keratinocyte desquamation
sry scaly skin
loss of normal barrier function
mutation in the filaggrin gene
Symptoms worsen with age and winter (less humidity)

Ichthyosis Vulgaris

19

ROUGH skin lesion in sun exposure
+ RISK of SCC

ACTINIC KERATOSIS

20

hyperkeratosis
parakeratosis
Epidermal hyperplasia
Acanthosis with CLUBBED RETE REGED

PSORIASIS

Silver scaling
+SPINOSUM

21

microorganism

NON- purulent cellulitis:
Purulent Cellulitis:

NON-purulent cellulitis: Strepto Grup A

Purulent cellulitis: Staphilococus aureus