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MSK & Connective Tissue > Pathology > Flashcards

Flashcards in Pathology Deck (6)
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1

genetic mutation of type V Collagen
def wich enzime

Ehlers-Danlos
procollagen peptidase (Cleavage of procollagen C- and N- chains)

2

Adolescent athlete
Knee pain worsen with Extension

Osgood-Schlatter Disease

Avulsion TIBIAL TUBERCULE (jumping)
Secondary ossification center

3

Paget disease of the Bone- Osteitis deformans
M-CSF & RANK-L -- NFkB Osteoclast / mixed / osteoblast
Sx.
Rx
Tx

Sx: bone thickening and hearing loss
Rx: Osteosarcoma
Tx: bisphosphonates

4

Gradual onset of symptoms
Pleuritic
Fever
Arthralgias
Erythematous rash

ask for...

Anti-double strand DNA antibodies
High Specificity

5

high Osm
-
low ICF
low ECF
cause?

Diabetes Insipidus
high serum osmolarity
low urine osmolarity

6

ANTICARDIOLIPIN...
LUPUS ANTICOAGULANT...
produce?

Antiphospholipid Syndrome
Anticardiolipin__ FALSE + VDRL/RPR
Lupus Anticoagulant__ kPTT prolonged (but)

HYPERCOAGULABILITY STATE
#Thrombosis
#Preganancy Loss-Abortion