Dermatopathology 2

Question 1

Cutaneous neoplasms

Answer 1

Epidermal neoplasms
- SCC
- papilloma

Question 2

Adnexal neoplasms

Answer 2

Hair follicle tumors
Sebaceous gland tumors
Apocrine gland tumors

Question 3

Dermal neoplasms

Answer 3

Soft tissue sarcoma
Feline vaccine associated sarcoma
Histiocytic neoplasms
Mast cell tumor
Lymphoma
Plasma cell tumors
Sarcoid
Lipoma
Vascular tumors

Question 4

SCC

Answer 4

Malignant neoplasms of squamous Epi cells
Locally invasive, recur locally - occur from UV radiation

Question 5

Papilloma

Answer 5

Exophytic papillary mass
PV infection - species specific
Common in YA & spontaneously regress

Question 6

Papilloma in species

Answer 6

Cattle
- sites of abrasion, ears, head, neck, teats
Horses
- face, nose, lips
Goats
- udder
Sheep
- head, ears
Dogs
- solitary or multi
- head

Question 7

Adnexal neoplasms

Answer 7

Hair follicle tumors
Sebaceous gland tumors
Apocrine gland tumors

Question 8

Hair follicle tumors

Answer 8

Trichoblastoma
Pilomatricoma
Trichoepithelioma

Question 9

Sebaceous gland tumors

Answer 9

Adenomas more common than adenocarcinoma
Perianal gland tumors

Question 10

Apocrine gland tumors

Answer 10

Adenocarcinoma s more common than adenomas

Question 11

Melanocytic neoplasms

Answer 11

Range from benign (melanocytoma) to malignant (melanoma)

Question 12

Melanocytic neoplasms in dogs

Answer 12

Lesions on haired skin = more likely benign
Oral cavity/lip = more likely malignant

Question 13

Melanomas in horses

Answer 13

Gray horses:
Benign melanomas = common
Arab, Lipizzaner, can argue, Percheron
Perineum, ^ age = increased in # tumors
Non gray:
Melanomas less common
More likely to be malignant

Question 14

Soft tissue sarcoma

Answer 14

Group of mesenchymal neoplasms w biological behavior
- Fibrosarcoma
- perivascular wall tumor (hemangiopericytoma)
- peripheral nerve sheath tumor
Graded based on appearence of morphological features

Question 15

Feline vaccine associated sarcoma

Answer 15

Highly malignant cutaneous associated w previous injection signs

Question 16

Histocytic neoplasia

Answer 16

Benign: cutaneous histiocytoma
Common in dogs < 2yr, in langerhans cells
Malignant: histiocytic sarcoma
Progressive & multifocal disease, met to viscera

Question 17

Mast cell tumors

Answer 17

Common in dogs, less in cats & horses

Question 18

Tumor grading mast cell tumors in dogs

Answer 18

Low grade vs high grade
SubQ MCT = better prognosis than cutaneous MCT

Question 19

Lymphoma

Answer 19

Cutaneous lymphoma = less common than visceral lymphoma
Epitheliotropic lymphoma
Bovine cutaneous lymphoma

Question 20

Epitheliotropic lymphoma

Answer 20

Mycosis fungoides
T cell lymphoma is a progressive disease
Variable presentation
Lesions are depigmented, erythema, scaling and alopecia

Question 21

Plasma cell tumor

Answer 21

Cutaneous plasma cell tumor
Typically affects dogs
Benign
Locations: haired skin & oral cavity

Question 22

Sarcoid

Answer 22

Most common skin tumor of horses**
Neoplasm of fibroblasts
Can be caused by BPV 1& 2 - WONT metastasize
Recurrence is very common

Question 23

Lipoma

Answer 23

Benign neoplasm of adipocytes
Very common in dogs
Complete excision usually curative

Question 24

Vascular neoplasms

Answer 24

Hemangioma - benign
Hemangiosarcoma - malignant