Development of Muscle and Nerve Flashcards

1
Q

intermeditae horn

A

cells for ANS, up to T spine and L spine

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2
Q

why neural crest cells are sometimes referred to as the 4th germ layer

A

neural crest cells are migratory. they are the derivative fo so many tissue types. they go up at the top of the fused neural tube then migrate away and down.

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3
Q

somatotopic organization of the developing brain stem and spinal cord

A

Dorsally: alar = sensory(dorsal horn),
Ventrally: basal, motor (ventral horn)

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4
Q

maternal diet in their prevention

A

folic acid bb

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5
Q

smooth and cardiac muscle derivative

A

visceral splanchnic mesoderm

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6
Q

Primary myogenesis

A

embryonic stage in the somites

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7
Q

dorsal side of spinal nerve

A

neural crest cells give rise to the dorsal root ganglion

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8
Q

what doe sthe myotome split up into

A

epimere: deep back/erector spinae muscles
hypomere: ventral, hypoaxial muscles

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9
Q

hydrocephalus

A

water head baby

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10
Q

rhombecephalon

A

hindbrain

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11
Q

what do neural blasts differentiate into

A

neurons

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12
Q

Three primary brain ventrivles

A

prosencephalon, mesencephalon,rhombecephalon

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13
Q

sclerotome

A

resegmentation occurs so that the nerve can go thru to the muscle

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14
Q

where does sensory and motor converge from the dorsal and ventral horns?

A

This leads to the spinal nerve itself

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15
Q

ventral side of spinal nerve

A

motor nerves via mantle layer of teh basal plate

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16
Q

neural tube defect

A

anencephaly and spina bifida. Anencephaly is where anterior neuropore doesn’t close, spina bifida is failure of caudal one to close

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17
Q

The ____ layer dfferentiates into the ___ of teh spinal cord

A

the marginal layer into the whiet matter

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18
Q

secondary brain vesicles

A

telencephalon, diencephalon, mesencephalon, metencephalon, myelencephalon

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19
Q

meningomyelocele

A

whole ass cord out

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20
Q

myotome

A

motor innervation

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21
Q

what does the myotome split up into

A

epimere: deep back/erector spinae muscles
hypomere: ventral, hypoaxial muscles

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22
Q

glial cell in CNS that produces myelin

A

oligodendrocytes

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23
Q

metencephalon

A

cerebellum and pons

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24
Q

What does the neuroepithelium surround

A

the neural tube

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25
Ventral pathway of neural crest cells
dorsal root ganglia, sympathetic chain ganglia, tehy all go thru the somites
26
which way does the dorsal root ganglion go
towards the alar plate and the receptors
27
what are the ventral and dorsal horns
for teh CNS and PNS
28
myelencephalon
medulla oblongata
29
What is a spinal nerve?
exit from the vertebrae, all of tehm are mixed for S or M
30
what is a ganglia
neural cell bodies outside of central nervous system
31
telencephalon
cerebrum ina dult
32
striated skeletal muscle derivative
somitomeres vai paraaxial mesoderm
33
hydrocephalus
water head baby due to blockage between the 3rd and 4th ventricles
34
somite differentiation into
dermatome, myotome, sclerotome
35
Dorsal pathway of neural crest cells
future melanocytes
36
ventricles of brain
has CSF
37
meningomyelocele
whoel ass cord out
38
mesencephalon
midbrain
39
Ventral pathway of neural crest cells
dorsal root ganglia, sympathetic chain ganglia, they all go thru the somites
40
Three primary brain ventrivles
prosencephalon, mesencephalon,rhombecephalon
41
Primary myogenesis
embryonic stage in the somites myoblasts fuse
42
neuroblasts will form the\_\_ layer which will lead to the ___ of the spinal chord
mantle layer to become the gray matter
43
prosencephalon
forebrain
44
meningocele
protrusion of the meninges
45
Rachischisis
no brain no back
46
outgrowing motor axons
convey motor info, connected to ventral side of spinal nerve
47
central canal
CSF,
48
Recall the process of neurulation
Where the neural plate folds in dorsally and fuse at the midline, neural groove --\> neural tube
49
dermatome
sensory portion
50
What can form if spina bifida happens
meningomyocele
51
Is when these cross in teh spinal cord
Decussation is when the roof and floor plates cross
52
Ventral root derives from the…
Cells of the basal plate
53
Dorsal root derives from the…
Neural crest cells where processes extend centrally to the alar plate
54
Polarity of dorsal root ganglion is
Pseudounipolar
55
Which end do axons grow from
Apical end
56
Chemoattractants
Wants griwth cone to go in right direction
57
Chemorepelents
Molecular signal that guides not to grow somewhere
58
Synaptogenesis is…
Not precises, so unused ones get apoptosed
59
Where does sclerotome separate for resegmentation
Caudal and cranial of two diff sclerotome segments fuse
60
What directs axonal growth
Growth cones towards synapse site
61
Metencephalon yields
Cerebellum and pons
62
Where does the cephalic flexure occur
Between mesencephalon and metencephalon
63
Rhombic lip turns into
Cerebellum
64
What separates the basal and alar plate
Sulcus limitans
65
Where to epyndemal cells live
In choroid plexus
66
Colliculi
Bumps
67
Substantia nigra
Movement
68
Crus cerebri
Leg of brain, from marginal region )midbrain
69
Diencephalon is
Anything in contact with third ventricle
70
What origin is pituitary gland
Ectoderm, neuroectoderm and oral ectoderm
71
where are these developed from
Pharyngeal arches, derived from neural crest cells and mesoderm
72
what is seen in pahrnygeal arches
pouchies, cleft, nerve, artery, vein,lined inside by endo, outside by ecto
73
Arch and each CN
1 :V3 2 : VII 3: IX 4 (& 6): X