Development Of The Head And Neck Flashcards

(43 cards)

1
Q

When does development of the head and neck start?

A

Day 22

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2
Q

Describe the head and neck at day 22 of development

A

No defined facial features
Head + neck take up half of length of embryo

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3
Q

What are the pharyngeal arches?

A

Five pairs of mesenchymal proliferations

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4
Q

Why are there only 5 pharyngeal arches but they are named 1,2,3,4+6?

A

The 5th pharyngeal arch is present for a few days before it breaks down

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5
Q

Describe the pharyngeal arches

A
  • outer ectoderm covering
  • inner endoderm lining
  • mesenchyme centre
  • each arch has an associated cranial nerve, vessels + cartilage bar
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6
Q

What are the associated cranial nerves to the pharyngeal arches?

A
  • 1: trigeminal V
  • 2: facial VII
  • 3: glossopharyngeal IX
  • 4+6: vagus X
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7
Q

What are the associated aortic arches of the pharyngeal arches?

A

Same as their number

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8
Q

What are the associated muscles of the pharyngeal arches?

A

1 - muscles of mastication
2 - muscles of facial expression
3- stylopharngeus muscle
4+6 - pharyngeal + laryngeal muscles

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9
Q

What are the associated skeletal elements of the pharyngeal arches

A

1 - mandible, malleus + incus
2 - stapes + superior part of hyoid
3 - inferior part of hyoid
4+6 - laryngeal cartilages

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10
Q

List the associated structures with pharyngeal arch 1:
- nerve
- aoritc arch
- muscles
- skeletal elements

A
  • trigeminal nerve V
  • 1st aortic arch
  • muscles of mastication
  • mandible, malleus + incus
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11
Q

List the associated structures with pharyngeal arch 2:
- nerve
- aoritc arch
- muscles
- skeletal elements

A
  • facial VII
  • 2nd aortic arch
  • muscles of facial expression
  • stapes + superior part of hyoid
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12
Q

List the associated structures with pharyngeal arch 3:
- nerve
- aoritc arch
- muscles
- skeletal elements

A
  • glossopharyngeal nerve IX
  • 3rd aoritc arch
  • stylopharyngeus
  • inferior part of hyoid
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13
Q

List the associated structures with pharyngeal arches 4+6:
- nerve
- aoritc arch
- muscles
- skeletal elements

A
  • vagus nerve X
  • 4th+6th aortic arch
  • pharyngeal + laryneal muscles
  • laryngeal cartilages
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14
Q

What are the aortic derivatives from the aortic arches?

A

1+2 - none
3 - common, internal + external carotid arteries
4 - aorta L + brachiocephalic R
6- pulmonary arteries

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15
Q

What are pharyngeal clefts?

A

Invaginations of ectoderm (outside)

Cleft - eCtoderm

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16
Q

What are pharyngeal pouches?

A

Inner spaces between the pharyngeal arches that form pockets of endoderm

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17
Q

What are the derivates of the pharyngeal pouches?

A

1 - tubotympanic recess > eustachian tube
2 - palatine tonsil
3+4 - parathyroid glands + thymus

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18
Q

What are the derivates of the pharyngeal clefts?

A
  • only the first cleft remains > external acoustic meatus
  • remaining clefts are obliterated by second cleft moving down over them
19
Q

What can form due to misobliteration of the pharyngeal clefts?

A

Branchial cysts, sinuses + fistulas

20
Q

What are the key components of development of the face?

A

Frontonasal process
Maxillary process
Mandibular process

21
Q

What does the frontonasal process become?

A

Forehead
Bridge of nose
Eyelids
Philtrum

22
Q

What does the maxillary process become?

A

Cheeks
Lateral upper lip
Lateral upper jaw
Sides of nose

23
Q

What does the mandibular process become?

A

Lower lip
Lower jaw

24
Q

Outline the development of the mouth

A
  • buccopharyngeal membrane disappears via apoptosis
  • stomodeum forms (end of foregut that forms the mouth)
25
Outline the development of the nose
- **nasal placodes** on either side of frontonasal process invaginate to form **olfactory/nasal pits** - these will become the **nostrils** - **nasal processes** + **maxillary processes** move medially + fuse to form the nose + philtrum in the midline
26
What is a placode?
Ectodermal thickening in the cranial region of the embryo
27
Outline the development of the mandible
Mandibular processes move medially + fuse
28
Outline development of the palate
- two **palatal shelves** grow from the internal side of the **maxillary processes** - **fuse with the primary palate** at the midline - this forms the **secondary palate** which separates the oral and nasal cavities
29
What is cleft palate?
Failure of fusion of the palatal shelves in the midline
30
What is a cleft lip?
Failure of fusion of the medial nasal process + maxillary process
31
Outline the development of the ears
- arise in association with 1st pharyngeal cleft (external acoustic meatus) - auricular hillocks (3 above-1st pharyngeal arch | 3 below-2nd pharyngeal arch) surround first pharyngeal cleft - these structures ascend to become external ear
32
What is fetal alcohol syndrome?
- condition that results from alcohol exposure during mother’s pregnancy - causes brain damage, growth problems + facial abnormalities
33
What impact does fetal alcohol syndrome have on the development of ears?
Low set ears due to interference of ascent
34
Outline the development of the tongue in regards to the pharyngeal arches
- **1st**: anterior 2/3 of tongue - **2nd+3rd** posterior 1/3 of tongue - **4th+6th**: epiglottis + glottis of larynx
35
What is the sulcus terminalis of the tongue?
Demarcation between the anterior 2/3 and posterior 1/3 of the tongue
36
Innervation of the tongue
- **anterior 2/3**: sensation from trigeminal nerve V | taste from facial VII - **posterior 1/3**: sensation + taste from glossopharyngeal IX
37
What is foramen caecum?
The point where the thyroid gland develops from
38
Where do the muscles of the tongue arise from?
Occipital somites At level of hypoglossal nerve
39
What is the motor supply of the tongue?
Hypoglossal nerve
40
Outline the development of the thyroid gland
- originates from foramen caecum - thyroid diverticulum grows down > thyroglossal duct - as thyroid descends the thyroglossal duct breaks down
41
What are thyroglossal cysts due to?
Failure of the thyroglossal duct to break down
42
Abnormalities of the development of the thyroid gland
- **thyroglossal cysts**: failure of the thyroglossal duct to breakdown - **ectopic thyroid gland tissue** can be left anywhere along the path of descent
43
Investigation + diagnosis of thyroglossal cysts
- fibrous band connects cyst to tongue - ask patient to stick their tongue out > cyst will elevate