Diabetes 1 Flashcards

(39 cards)

1
Q

Diabetes mellitus

A

A chronic disease related abnormal insulin production( disprder of the pancreas)
Impaired insulin utilisation
Characterized hy hyperglycemia

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2
Q

Normal glucose level

A

4-7.8 mmol/l (diabetes aus)

3.9- 6.1 mmol/l ( brown)

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3
Q

Regulation of blood glucose level

A

Pancreas

Liver

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4
Q

Pancreas

A

A digestive and endocrine gland

Endocrine function: Secretes glucose, insulin , somatostatin

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5
Q

Liver

A
Glucose metaolism
Glycogen storage
Glycogenesis
Glycogenolysis
Regualtion of blood glusoce concentration
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6
Q

Normal insulin metabolism

A
Only hormone that directly lowers bgl
Produced by b cells in islet of
langerhan 
Promotes glucose transport across cell memebranes
Stimulates glycogenesis, glycogenolysis
Increase protoen synthesis
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7
Q

Glycogenesis

A

Storage of glucose as glycogen

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8
Q

Hormones that opsoe the effects of insulin

A

Glucagon , epinephrine, growth hormone, cortisol
Stimulate glucose production by liver
Decrease movement of glucose

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9
Q

Type 1 diabetes

A

No insulin being produced

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10
Q

Type 2 diabetes

A

Person is resistant to the insulin being produced

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11
Q

Diabetes aetiology

A

Person eats/drinks-
Blood glucose rises
Vete cells in pancreas detect rise in blood glucose
Pancreas releases insulin into the blood
( 1 : no insulin 2: resistant to insulin)
Tissue cells take up glucose
Blood glucose falls

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12
Q

Diabetes 1 risk factor

A

Not inherited, but genetic predisposition combined with immunologic and possibly environmental factor

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13
Q

Type 2 diabetes risk factor

A
Family history 
Race
Pbese
Poor nutrition 
Smoking
High bp
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14
Q

Clinical manifestation of high bgl

3 ps

A

Polyuria: urine
Polydipsia: excessive thrist
Polyphagia : excessive hunger

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15
Q

Other symptoms of high bgl

A
Weight loss
Weakness
Blurred vision
Headache
Numbness of feet
Wounds slow to heal
Recurrent infection
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16
Q

Classifications of diabetes

A
Type 1
Type 2 
Gestational
Pre diabetes 
Secondary diabetes
17
Q

Type 1 diabetes

A

Insulin producing b cells in pancreas destroyed by autoimmune process
No insulin production

18
Q

Wffects of lack of glucose in insulin production

A
Catabolism
Adipogenesis
Glycogenesis 
Result
- poor utilisation of glucose lead to feeling of hunger, tiredness, increased breakdown of alternate engery sources
19
Q

Catabolism

A

Impeded due to the lack of transport of glucose into the cytoplasm

20
Q

Adipogenesis

A

Glucose conversion into fattty acid is limited due to the lack of insulin

21
Q

Glycogenesis

A

Glucose is stored in liver and muscle as glycogen. This is activated by insulin l, therefore limited

22
Q

Treatment of type 1 diabetes

A

Insulin injections

23
Q

Type 2 diabetes

A

Pancreas continues to produce insulin by insufficient or poorly utilised by body

24
Q

Pathophysiology of type 2 diabetes

A

Insulin resistance
Decreased insulin production
Increased glucose production
Altered production of hormones and cytokines bu adipose tissue

25
Type 2 diabetes symptoms
Slow progressive glucose intolerance Hyperglycaemia Asymptomatic for years byt type 1 diabetes may be experienced
26
Treatment of type 2 diabetes
Treated initially with diet and exercise Oral hypoglycemic agents may be used Insulin may ultimately
27
Prediabetes
High risk for type diabetes 2 Have impaired glucose tolerance Asymptomatic but long-term damage already occuring Undergo screening Manage risk factors Monitor for symptoms of diabetes Maintain healthy weight, exercise, healthy diet
28
Gestational diabetes
Glucose intolerance develops during pregnancy Management Similar to type 2 diabetes Dietary modification Oral agents avoided Post pregnancy Bgl levels return to norma after delivery (6weeks) Increased risk of developing type 2 diabetes early in life
29
Secondary diabetes
Can result form damage or injury, interferance , destruction of b cells in the pancreas medications, medical conditions Can be resolved if condition is treated or medication is didscontinued
30
Management of diabetes mellitus primary goal
Keep blood sugar level simlar as normal as possible | Normalize activity of insulin and glucose
31
Other goal management of diabetes
Reduce symptoms Promote wellbeing Prevent acute complication Delay long term complications
32
Major components of care
``` Patient teaching Self monitoring of bgl Nutritional therapy Exercise Pharmacologic therapy ```
33
Multidisciplinary care
Multidisciplinary team train is diabetes care is managaing the patient
34
Diagnosing and monitoring diabetes
Fasting blood glucose >=7.0mmol/L Random plasma glucose >=11.1 mml/L 2 hour OGTT>= 11.1 mmol/L HbA1c>=6.5%
35
Self monitoring of BGL
With insulin- 2-4 times a day , before meals and at bedtime | No insulin: 2 hours before and after the largest meal(2-3 times per week)
36
Type 1 diabetes target range
4-8 mmol/l before meals | >10 mmol/L two hours after starting meal
37
Type 2 diabetes bgl target range
6-8 mmol/L before meals | 6-10 mmol/L 2 hours after meals
38
Risk of hypoglycaemia bgl range
Less than 4mmol/L if insulin or certian type of tables are used
39
Blood glucose monitoring nursing considerations
Nurse competency Quality control tests of blood glucose meter - once dailt or new strips or new machine or new batteries - high and low range testing - documentation in logbook Lancet use - sharps precautions, ppe