Diabetes

Question 1

Which DM med works in the gut and inhibits the absorption of carbs from the brush border of the intestines?

Answer 1

Alpha Glucosidase Inhibitors

Question 2

What medications are indicated for children (>10yo) with diabetes?

Answer 2

Metformin and insulin

Question 3

Which DM Med must you skip a dose if you skip a meal and add a dose if you add a meal?

Answer 3

Meglitinides

Question 4

Which DM Med is most at risk for hypoglycemia?

Answer 4

Sulfonylureas

Question 5

How long must you hold Metformin when having iodinated contrast?

Answer 5

Day of and 48 hours after

Question 6

Which DM Med has a black box warning against use with CHF?

Answer 6

TZDs

Question 7

Which DM drug class can cause hypotension?

Answer 7

SGLT2 inhibitors (due to volume loss)

Question 8

Sulfonylureas cannot be used in patients that have a cross-sensitivity to what two drug classes?

Answer 8

Sulfonamides or thiazides diuretics

Question 9

Acute pancreatitis is a contraindication for which DM Med?

Answer 9

GLP-1

Question 10

It’s normal to have glucose in urine with which DM Med?

Answer 10

SGLT2 inhibitors

Question 11

Which DM Med interacts with oral contraceptive pills and will need backup?

Answer 11

TZDs

Question 12

Which DM drug class has compliance issues due to increased flatulence?

Answer 12

Alpha Glucosidase Inhibitors

Question 13

Which drug class is contraindicated for bladder cancer?

Answer 13

TZDs

Question 14

Which DM Med is well tolerated in the elderly?

Answer 14

DPP-4s

Question 15

Which DM Med can also improve lipid profile?

Answer 15

Metformin (Biguanide)

Question 16

Which DM Med can increase TG levels

Answer 16

Actose (a TZD)

Question 17

What are the diagnostic criteria for diabetes?
HbA1C >= \_\_\_\_
FPG >= \_\_\_\_
OGTT >= \_\_\_\_
Random plasma glucose >= \_\_\_\_

Answer 17

HbA1C >= 6.5%
FPG >= 126 mg/dL
OGTT >= 200 mg/dL
Random plasma glucose >= 200 mg/dL

Question 18

Gestational diabetes is caused by what?

Answer 18

Placental hormones.

-They have an anti-insulin effect and increase glucose resistance

Question 19

History of pancreatitis is contraindicated for which DM Med?

Answer 19

DPP-4 inhibitors

Question 20

What is the HbA1C goal drug therapy for DM according to ADA?

Answer 20

<7%

Question 21

Which two antihypertensives can Diabetic patients take?

Answer 21

ACE or ARB because they are renal protective

Question 22

Lactic acidosis is a rare complication of which DM Med?

Answer 22

Metformin

Question 23

The two DM meds that cause weight gain are ______ and _______.

Answer 23

TZDs and Sulfonylureas

Question 24

What abx can cause hypoglycemia?

Answer 24

Sulfonamides and tetracyclines