Diagnostics Flashcards
TEG
R- reaction time, time of onset to fibrin formation
K-rate of fibrin formation
alpha- rate of fibrin formation
MA- strength of clot
Lys30 and Lys60- percentage of the fibrin clot that has lysed at 30 and 60 minutes
ROTEM
CT- clot time
CFT- clot formation time
MCF- maximum clot firmness
Hypercoagulable
Time until onset of fibrin formation- short R/CT
Rate of fibrin formation- short K, high alpha/ short CFT
Strength of fibrin clot- high MA/ MCF
Hypocoagulable
Time until onset of fibrin formation- long R/CT
Rate of fibrin formation- long K, low alpha/ long CFT
Strength of fibrin clot- low MA/MCF
How does hct affect TEG results?
Lower hematocrits lead to hypercoagulable tracings with higher hematocrits causing the opposite trend. This is thought to be an artifact of the change in red blood cell number versus reflecting a real change in vivo. This severely impacts the use of this test to diagnose hyper- and hypercoagulable disorders in anemic or polycythemic patients.