Dialysis Flashcards

1
Q

What is Dialysis?

A

Diffusion of molecules in solution across a semi-permiable membrane along an electrochemical conc. gradient

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2
Q

What is the goal of dialysis?

A

Restore the intracellular and extracellular fluid envt char of normal kidney funct

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3
Q

What are the common S and S of Uremia?

A
Hypothermia
Serositis (pericarditis)
Itching(phos retention)
Hiccups
etc...
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4
Q

What are the indications for Renal Replacement therapy?

A
AEIOU
Acidosis
Electrolytes (K+)
Ingestions (drugs, toxins)
Overload-refractory fluid OL
UREMIA
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5
Q

What is the level of GFR that indicates a need for Dialysis?

A

less than 15mL/min/1.73m2

Not looking for a number (AEIOU)

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6
Q

What are the two Physical Principles that drive Dialysis?

A

Diffusion- Conc gradient

Convection- Trans membrane pressure- Removes water and solutes

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7
Q

What facotrs determine the level of Diffusive transport in Dialysis?

A
Conc diff
Membrane Surface area
Porosity and thickness of the membrane
Molecule size of solute
Flow rate of blood and dialysate
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8
Q

What facotrs determine the level of Convective transport in Dialysis?

A

Fluid (water transport)
Solutes dragged with fluid
Dependant on sieving Coeff

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9
Q

What is clearance?

A

Volume of plasma completely cleared of a substance per unit time

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10
Q

What is the most common secondary cause of death in a dialysis patient?

A

Infection

Cardiovascular

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11
Q

What are the key components of a Dialysis order?

A

Tx time, Freq
Flow rate of blood and dialysate
Dialysate composition: Na, K, Ca, Mg, Buffer, Cl, Glu

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12
Q

What are the determinants of Dialysis Efficiency?

A
Membrane Char
Membrane SA
Blood Flow rate
Dialysate flow rate, char
Duration of dialysis
Utrafiltration
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13
Q

What are the complications of dialysis?

A
HypoTension
Arrhythmias
Muscle Cramping
N/V
Disequilibreum
Hypoxemia
Anaphylactoid Rxns
Vascular Access related
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14
Q

What is the Makeup of the peritoneal Dialysis Solution?

A

Standard electrolyte comp
GLucose in variable conc to draw off extra fluid
Amino Acids
Icodextrin

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15
Q

What are the positives for Peritoneal Dialysis?

A
Self care
Control over schedule/freedom
Once/month clinic
no needles
more steady physical cond
less restrictive diet
less expensive
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16
Q

What are the complictions of Peritoneal Dialysis?

A
Peritonitis
Catheter infection
Cath malfunction
Loss of ultrafiltration
hyperglycemia/wt gain
Malnutrition