Dialysis Flashcards
What is Dialysis?
Diffusion of molecules in solution across a semi-permiable membrane along an electrochemical conc. gradient
What is the goal of dialysis?
Restore the intracellular and extracellular fluid envt char of normal kidney funct
What are the common S and S of Uremia?
Hypothermia Serositis (pericarditis) Itching(phos retention) Hiccups etc...
What are the indications for Renal Replacement therapy?
AEIOU Acidosis Electrolytes (K+) Ingestions (drugs, toxins) Overload-refractory fluid OL UREMIA
What is the level of GFR that indicates a need for Dialysis?
less than 15mL/min/1.73m2
Not looking for a number (AEIOU)
What are the two Physical Principles that drive Dialysis?
Diffusion- Conc gradient
Convection- Trans membrane pressure- Removes water and solutes
What facotrs determine the level of Diffusive transport in Dialysis?
Conc diff Membrane Surface area Porosity and thickness of the membrane Molecule size of solute Flow rate of blood and dialysate
What facotrs determine the level of Convective transport in Dialysis?
Fluid (water transport)
Solutes dragged with fluid
Dependant on sieving Coeff
What is clearance?
Volume of plasma completely cleared of a substance per unit time
What is the most common secondary cause of death in a dialysis patient?
Infection
Cardiovascular
What are the key components of a Dialysis order?
Tx time, Freq
Flow rate of blood and dialysate
Dialysate composition: Na, K, Ca, Mg, Buffer, Cl, Glu
What are the determinants of Dialysis Efficiency?
Membrane Char Membrane SA Blood Flow rate Dialysate flow rate, char Duration of dialysis Utrafiltration
What are the complications of dialysis?
HypoTension Arrhythmias Muscle Cramping N/V Disequilibreum Hypoxemia Anaphylactoid Rxns Vascular Access related
What is the Makeup of the peritoneal Dialysis Solution?
Standard electrolyte comp
GLucose in variable conc to draw off extra fluid
Amino Acids
Icodextrin
What are the positives for Peritoneal Dialysis?
Self care Control over schedule/freedom Once/month clinic no needles more steady physical cond less restrictive diet less expensive