Digestiive System Flashcards
________ in food cannot be utilised by our body in their ORIGINAL form .
BIOMACROMOLECULES
In 1851 , ___ published a paper describing a structure located on the basilar membrane of the cochlea containing hair cells that convert sound vibrations into nerve impulses .
Alfonso corti
BIOMACROMOLECULES in our food have to be broken down into simple _______ forms . This is called digestion .
Absorbable
Digestion is carried out by our digestive system by _____and ____ method .
Mechanical
Biochemical
The human digestive system consists of the ____ and the ______.
Alimentary canal
Associated glands
The alimentary canal begins with the _____opening -the ____ and it opens _____ through the anuss .
Anterior
Mouth 👄
Posteriorly
The mouth leads to the ____ or _____.
Buccal cavity
Oral cavity
The _____cavity has a number of teeth .
Oral cavity
The oral cavity consists of ___and ____.
Teeth
muscular Tongue
Each tooth is embedded in a _____of ____.
Socket
Jaw bone 🦴
Each tooth is attached in a socket of jaw bone , this type of arrangement is called -
Thecodont
Majority of ______form 2 sets of teeth in their life .
Mammals including humans
The type of dentition in which a set of temp milk teeth or deciduous teeth is replaced by a set of permanent teeth or adult teeth , is called -
Diphyodont
An adult human has 32 permanent teeth which are of 4 diff teeth , this dentition is called -
Heterodont
Dental formula of an. Adult human teeth -
2123
——
2123
The hard chewing surface of teeth made up of _____ helps in the ______ of food .
Enamel
Mastication
The tongue is a _____ muscular organ attached to the _____ of ____ by the FRENULUM .
Freely movable
Floor
Oral cavity
The _____ surface of the tongue has small PROJECTIONS called ______
Upper
Papillae
Some ___bear taste buds .
Papillae
The oral cavity leads into a short _______.
Pharynx
___serves as a common passage for food and air .
Pharynx
The ___ and ____ open into the pharynx
Oesophagus
Trachea
A cartilaginous flap , EPIGLOTTIS prevents the entry of food 🥘 into the ______ during swallowing.
Glottis -opening of wind pipe (trachea )
The ______ is a thin tube extending posteriorly passing through the neck ,thorax and diaphragm .
Oesophagus
Oesophagus leads to a ___ shaped structure called stomach .
J
A muscular sphincter - _______ regulates the opening of oesophagus into the stomach .
Gastro-oesophageal sphincter
The stomach located in the _______ portion of the abdominal cavity .
Upper left
What are the parts of the stomach ?
4 Cardiac -into which oesophagus opens Fundus - Body -main central region Pyloric -opens into the intestines
_____ pat of stomach opens into the small intestines .
Pyrolic
Small intestine is distinguishable regions - a _____ shaped duodenum , middle ____ jejunum , and a _____ coiled ileum .
C
Long coiled
Highly
The opening of the stomach into the duodenum ids guarded by -
Pyloric sphincter
__ opens into the large intestines .
Ileum
Large intestine consists of ____,____and ____.
Caecum
Colon
Rectum
_____is a blind sac that hosts some _____ microorganisms .
Caecum
Symbiotic
A narrow finger-like tubular projection , the ______ which is a vestigial organ arises from the. ______.
Vermiform appendix
Caecum
The ___opens into the colon .
Caecum
The colon is divided into how many parts ,what ?
4 Ascending colon Transverse colon Descending colon Sigmoid colon
The _____ part of the large intestine opens into the rectum , which opens out through the anus .
Descending
not sigmoid -though it is the last part
The wal of the alimentary canal from ___ to _____ possesses 4 layers .
Oesophagus
Rectum
___ is the outermost layer of the alimentary canal and is made up of a _________ with some _______ .
Serosa
Thin mesothelium ( epithelium of visceral organs )
Connective tissue
___ is the epithelium of visceral organs ( like alimentary canal )
Mesothelium
In serosa
Muscularis layer is made up of ______ .
Smooth muscles .
The muscularis is layer has 2 parts : inner ____layer and outer ____layer .
Circular
Longitudinal
(An oblique muscle layer may be present in some regions )
An oblique muscle may be present in which layer of alimentary canal .
Muscularis
The sub-mucosal layer is formed of _____tissues containing __,_____and ____ .
Loose connective tissues
Nerves
Blood 🩸
lymph vessels
In duodenum , gland are present in the ________
Sub-mucosa
The innermost layer lining the lumen of the alimentary canal is the -
Mucosa
Which layer forms irregular folds in the stomach .
Mucosa
The mucosa forms irregular folds- ____ in the stomach and small finger-like foldings called - ____in the small intestine .
Rugae
Villi
The cells lining the villi produce numerous ,microscopic projections called _____ giving a ______appearance.
Microvilli
Brush-border
The villi and microvilli inc the ______ ENORMOUSLY .
SA
__ are supplied with a network of capillaries and the lacteal ( large lymph vessel )
Villi
Mucosal epithelium has ______ cells , which secrete mucus that help in lubrication .
Goblet
Mainly intestinal mucosa has goblet cells
Villi are supplied with _____ and _____.
Network of capillaries
Large lymph vessel -lacteal
______ also forms gland in the stomach .which gland ?
Mucosa
Gastric gland
Mucosa forms __ int he stomach and ____ in between the bases of villi in intestine .
Glands
Crypts ( crypts of lieberkuhn)
All the 4 layers show modifications in diff parts of the alimentary canal .T/F
T
____layer of alimentary canal has goblet cells .
Mucosal epithelium (Mainly intestinal mucosa has goblet cells )
__ hosts some symbiotic microorganisms 🦠 .
Caecum (not vermiform appendix - it is just a part of caecum )
(Caecum- 1st part of large intestine )
___ layer of alimentary canal is made of thin ,ESOTHELIUM
Serosa
With some connective tissue
____ layer is formed of loose connective tissue contain nerves ,blood ,lymph vessels .
Sub-Mucosa
In ______ glands are present in sub-mucosa
and mucosa forms glands in _____.
Duodenum
Stomach
The digestive glands associated with the alimentary canal include-
Salivary glands
Liver
Pancreas
Saliva is produced by ______of salivary glands .
3 pair
The __ glands are present in the cheek .(salivary )
Parotid
The ____are present in the LOWER JAW .(salivary glands)
Sub-maxillary/ sub-mandibular
The ______are present BELOW THE TONGUE .(salivary glands )
Sub-linguals
Where are the salivary glands situated ? Where do they secrete saliva ?
Just Outside the buccal cavity
Secrete salivary juice into the buccal cavity
_____ is the largest GLAND of the body weighing about _______ in an adult human .
Liver
1.2 -1.5 kg
Location of liver ?
In the abdominal cavity , just below the diaphragm
The liver has __ lobes .
2
The _____are the structural and functional units of liver containing ______ arranged in the form of ______.
Hepatic lobules
Hepatic cells
Cords
Each hepatic lobule is covered by a ________ sheath called ______.
Thin connective tissue sheath
Glisson’s capsule
The bile is secreted by the _____ cells and it passes through the _______ ducts to get stored in the gall bladder .
Hepatic
Hepatic
Bile is ____and ____ in a thin muscular sac -gall bladder .
Stored
Concentrated
The ______ duct along with ____ duct forms the common BILE DUCT .
Duct of gall bladder (CYSTIC DUCT )
Hepatic duct - from liver
The ____and ____duct open together into the DUODENUM as the COMMON ________ duct
Bile duct (common)
Pancreatic duct
Common HEPATO-PANCREATIC duct
The opening of HEPATO-PANCREATIC duct into the _____is guarded by the _____sphincter
Duodenum
Sphincter of ODDI
The pancreas is a _____organ situated btw the ____of the C-shaped duodenum
Compound(both exo and endo )
Limbs
What does the exo and endo crine parts of pancreas secrete -
Exocrine -alkaline pancreatic juice containing enzymes
Endocrine -hormones ,insulin, glucagon
The main functions performed by BUCCAL CAVITY -
2
Mastication of food
Facilitation of swallowing
The __and the ___ with the help of ___ , masticate and mix the food thoroughly .
Teeth 🦷
Tongue 👅
Saliva
MUCUS in SALIVA helps in ___and___ the masticated food particles into a BOLUS .
Lubricating
Adhering
The bolus is conveyed into the pharynx and then into the oesophagus by ___or ____ .
Swallowing
Deglutition
The bolus further passes through the oesophagus by successive waves of ____ called _____.
Muscular contractions
Peristalsis
The ___controls the passage of food into the stomach .
Gastro-oesophageal sphincter
The saliva secreted into the ORAL CAVITY contains ELECTROLYTES like ___,____,___ and __ .
Na +
K+
Cl-
HCO3-
The enzymes contained in SALIVA are -
salivary amylase
Lysozyme
The _____process of digestion is initiated in the oral cavity by the _____ action of salivary amylase .
Hydrolytic
Chemical
Salivary amylase is a _______enzyme whose ______action initiates digestion .
Carbohydrate splitting
Hydrolytic
About _____% of STARCH is hydrolysed in the oral cavity .
30%
Salivary amylase is active at a pH _______ present in the oral cavity.
6.8
Slightly acidic
____present in the saliva acts as an antibacterial agent that prevents infections .
Lysozyme
About 30 % starch is hydrolysed in the oral cavity by salivary amylase (optimum pH6.8 ) into a _____-____ .
Disaccharide
Maltose
The ______of stomach has GASTRIC GLANDS
Mucosa
Gastric glands have how many major types of cells ? Name them -
3
Mucus neck cells.
Peptic/chief cells
Parietal /oxyntic cells
______cells of the gastric gland secrete MUCUS .
Mucus neck cells
Peptic cells of gastric glands of stomach secrete ______ .
Proenzyme pepsinogen
Gastric lipase
Parietal cells of gastric gland in the stomach secrete ____and_____.
HCL Intrinsic factor (responsible for absorption of vit B12)
Proenzyme pepsinogen is secreted by _____ cells .
Peptic / chief
Factor essential for the absorption of B12 is secreted by -
Oxyntic /parietal cells of gastric glands
The stomach stores the food for ______ hours .
4-5
The food mixes thoroughly with the ______ of the stomach by the ____ movement of its ___walls and is called the CHYME .
Acidic gastric juice
Churning
Muscular walls
The _____on exposure to HCL gets converted to the active enzyme PEPSIN of the ______.
Proenzyme pepsinogen
Stomach (pepsin is the active enzyme of the stomach )
Pepsin coverts ___into _and _____.
Proteins
Proteoses
Peptones(peptides)
The ____and _____in the gastric juice play an imp role in lubrication and protection of the mucosal epithelium (from highly conc HCL)
Mucus
Bicarbonates
HCL provides ____ pH optimal for ____.
Acidic =pH 1.8
Pepsins
Rennin is a _____enzyme found in the __of infants which helps in the digestion of milk proteins .
Proteolytic (protein breaking )
Gastric juice
What is the function of mucus and bicarbonates in the GASTRIC JUICE ?
Imp role in lubrication , and protection of the mucosal epithelium from excoriation by the highly conc HCL.
Small amounts of _____are also secreted by the gastric glands .
Lipases
Various types of movements are generated by the ___layer of the small intestines .
Muscularis
The __, ____ and ____are the are the secretions released into the SMALL INTESTINES .
BILE
Pancreatic juice
Intestinal juice
Give a brief account of the process of digestion taking place in the STOMACH -
HCl concerts proenzyme pepsinogen into pepsin
Pepsin converts proteins into proteoses and peptones(peptides )
Rennin is the proteolytic (similar to pepsin ) in infants
Lipases are also present here
____and ___ are released through the HEPATOPANCREATIC DUCT in the small intestines ( duodenum ).
Pancreatic juice
Bile
The pancreatic juice (released into the duodenum ) contains INACTIVE enzymes - ______________
6 Trypinogen Chymotrypsinogen PROCARBOXYPEPTIDASE Amylases Lipases Nucleases
The pancreatic juice has ______enzymes .(active/inactive )
Inactive
_____is activated by an enzyme ENTEROKINASE secreted by ______.
Trypsinogen
Intestinal mucosa
Types in is converted into its active form ,which is ______ (by enterokinase ) which in turn activates other enzymes present in the ______.
Trypsin
Pancreatic juice
(Trypsinogen—->trypsin—>activates other enzymes )
This takes place in the small intestines (duodenum )
ENTEROKINASE is secreted by the ______.
Intestinal mucosa
The bile released into the DUODENUM contains ______,____,____and _____ .
Bile pigments (bilirubin ,biliverdin)
Bile salts
Cholesterol
Phospholipids
Bile secreted into duodenum (through hepaatopancretic duct ) does not contain _____
Enzymes
Bile has no enzymes
Function of bile -
1) Helps in emulsification of fats ( breakdown of fats into small micelles )
2) Activates LIPASES
___activates lipases in the small intestines (duodenum )
Bile
Emulsification of fats is the breakdown of fats into ___
Small micelles
The _________has GOBLET CELLS.
INTESTINAL MUCOSA
In the intestine , __cells secrete mucus , and in the stomach ____cells secrete mucus .
Goblet cells (in the mucosal epithelium of intestines) Mucus neck cells ( in the mucosa of stomach )
The secretions of the brunch-border cells of the mucosa along with the secretions of the GOBLET CELLS constitute ______.
Intestinal juice /succus entericus
What constitutes the intestinal juice/succus entericus ?
Secretions of brush border cells of mucosa +secretions of goblet cells (of mucosa )
Which enzymes does succus entericus contain ?
Variety of enzymes like- Disaccharidases (maltase) Dipeptidases Lipases Nucleosidases
The functions of MUCUS and BICARBONATES in the small intestines -
1) Protect the intestinal mucosa from acid
2) provide an alkaline medium (pH 7.8)for enzymatic activities
The bicarbonates released into the small intestines ( to provide alkalinity ) are from -
Pancreas
Which pH does mucus and bicarbonates provide in the small intestines ?
Alkaline - pH 7.8
____ ,____and __ provide the intestinal mucosa from acid and also provide alkalinity (pH7.8) .
MUCUS
Bicarbonates
BRUNNER’S GLAND (sub-mucosal )
A SUB-MUCOSAL gland which functions along with mucus and bicarbonates -
BRUNNER’S gland
____,__and __Are partially hydrolysed proteins in the chyme .
Proteins
Proteoses
Peptones
Partially hydrolysed proteins reaching the small intestines are acted upon by the _____enzymes of _____.
Proteolytic enzymes (protein breaking ) PANCREATIC JUICE 🥤
Partially hydrolysed proteins (proteins ,proteoses and peptones ) are converted to ____ in the ______ .
diPeptides
Small intestines
Proteins ,peptones and proteoses are converted to diPeptides in the small intestine by the action of which enzymes ?
Trypsin
Chymotrypsin
CARBOXYPEPTIDASE
(1st of all , enterokinase converted trypsinogen into active trypsin , thin trypsin further converted chymotyrpsinogen and procarboxypeptidase into ACTIVE chymotrypsin and carboxypeptidase )
Carbohydrates in the chyme are hydrolysed by ________ into _____.
Pancreatic amylase
Disaccharides
(In the small intestines )
In the __,fats are broken down by ___with the help of ___ into DI and MONO -GLYCERIDES .
Small intestines
Lipases
Bile
Is any amount of fat digested in the stomach also ?
Lipases are present in the stomach, but not bile
So maybe some of it is partially hydrolysed*
Fats are broken down into __and ___ in the small intestines .
Di-glycerides
Mono-glycerides
(By the action of lipase along with bile )
What role does AMYLASE play in the small intestines ?
It converts polysaccharides(starch) into disaccharides (maltose )
It plays almost the same role as it does in the mouth
______ in the pancreatic juice act on NUCLEIC ACIDS to form _____and _____ .(in small intestines )
Nucleases
Nucleotides
Nucleosides
Does the small intestine secrete any enzyme or al enzymes i it come from pancreas ?
Both
Intestinal juice And Pancreatic juice both act in the small intestines
(After the pancreatic juices have acted on the chyme , the succus entericus plays its part and acts on the breakdown products of the enzymes of pancreatic juices )
The enzymes in the ______ act on the end products of the rxns catalysed by pancreatic enzymes (amylase ,lipase ,nucleases ,trypsin ,chymotypsin and carboxypaptidase )to form the respective simple ___forms .
Succus entericus
Absorbable
What are the final steps in digestion ?
Rxns catalysed by enzymes of succus entericus (dipeptidase , maltase , lactase , nucleotidases ,nucleosidases ,sucrose ,lactase
The final steps in digestion occur very close to the ______ of the _____ .
Mucosal epithelial cells
Intestine
The breakdown of the BIOMACROMOLECULES ( by the enzymes of the succus entericus , the final steps of digestion ) occur in the ___region of the small intestines .
Duodenum
The simple substances formed in the last steps of digestion in the duodenum region are absorbed in the ____and ____ regions of the small intestines .
Jejunum
Ileum
In the final steps of digestion (in duodenum) , DIPEPTIDES are converted to _____by ___ .
Amino acids
Dipeptidases (ofsuccus entericus )
Maltose(disaccharide )formed from starch (polysaccharide ) is converted to ________ by _____ in the last step .
Glucose+glucose
Maltase ( of succus entericus )
Lactose is converted to __ and ___ by the action of enzymes of_____.
Glucose
Galactose
Intestinal juice ( succus entericus )—- lactase
Sucrose left is finally converted to _____and ____ by ____.
Glucose
Fructose
Sucrase (of succus entericus )
In the final steps of digestion occurring in the duodenum , NUCLEOTIDES are converted to ______ by ______ , which are in turn converted to ____ by______.
Nucleosides
Nucleotidases
Sugars+bases
Nucleosidases
The final product of nucleic acids is -
Sugars + bases
Nucleic acids ————>nucleotides and nucleosides (pancreatic juice-nucleases )
Nucleotides ————> nucleosides——> sugars+bases (intestinal juice -nucleotidases,nucleosidases)